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This meeting took place in 2021
Here are the related meetings in 2024:
Immunometabolism: From Mechanisms to Pathways to Therapies (C3)
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Integrating Metabolism and Immunity (EK16)
Organizer(s) Marc Y. Donath, Tom Thuren, Bruce M. Spiegelman and Diane Mathis
January 25—28, 2021
Virtual at your computer • , CO USA
Abstract Deadline: Dec 16, 2020
Scholarship Deadline: Nov 1, 2020
Discounted Registration Deadline:
Sponsored by AbbVie Inc., Astellas Pharma Inc., Cell Research, Merck & Co., Inc. and Novo Nordisk A/S
Joint Meeting:
Tumor Metabolism and the Microenvironment (EK14)
Summary of Meeting:
Traditionally, metabolism and immunity have been perceived as two distinct systems with distinct functions: metabolism regulates the disposal and transformation of nutrients, whereas the immune system is responsible for host defense. However, in a broader sense, these two processes are both an organism’s response to stressors, with the aim of restoring homeostasis. An increasing amount of evidence has demonstrated that the chronic activation of the immune system associated with overnutrition may be deleterious, contributing importantly to diabetes and long-term complications, such as cardiovascular disorders. Such dysregulation of the immune system may reflect the duration and magnitude of the metabolic stress, along with genetic predispositions. Accordingly, anti-inflammatory treatments of metabolic diseases emerge as therapies interfering with the pathogenesis of these illnesses and offer disease-modifying potential. Therefore, it is critical that clinical translation be based on an understanding of the physiology and pathophysiology of the role of the immune system in metabolism. This conference will bring together basic scientists and clinicians from both disciplines in order to spark innovative ways of understanding the interactions between the immune system and metabolism. The conference organizers anticipate that the conference will lead to the development of novel therapeutic concepts based on the pathways underlying the pathogenesis of diseases rather than on the manifestation of symptoms belonging to a specific clinical discipline.
View Scholarships/Awards
Traditionally, metabolism and immunity have been perceived as two distinct systems with distinct functions: metabolism regulates the disposal and transformation of nutrients, whereas the immune system is responsible for host defense. However, in a broader sense, these two processes are both an organism’s response to stressors, with the aim of restoring homeostasis. An increasing amount of evidence has demonstrated that the chronic activation of the immune system associated with overnutrition may be deleterious, contributing importantly to diabetes and long-term complications, such as cardiovascular disorders. Such dysregulation of the immune system may reflect the duration and magnitude of the metabolic stress, along with genetic predispositions. Accordingly, anti-inflammatory treatments of metabolic diseases emerge as therapies interfering with the pathogenesis of these illnesses and offer disease-modifying potential. Therefore, it is critical that clinical translation be based on an understanding of the physiology and pathophysiology of the role of the immune system in metabolism. This conference will bring together basic scientists and clinicians from both disciplines in order to spark innovative ways of understanding the interactions between the immune system and metabolism. The conference organizers anticipate that the conference will lead to the development of novel therapeutic concepts based on the pathways underlying the pathogenesis of diseases rather than on the manifestation of symptoms belonging to a specific clinical discipline.
View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference
The meeting will begin on Monday, January 25 with . Conference events conclude on Thursday, January 28 with a closing plenary session from 12:00 to , followed by . We recommend return travel on Friday, January 29 in order to fully experience the meeting.
MONDAY, JANUARY 25
TUESDAY, JANUARY 26
WEDNESDAY, JANUARY 27
THURSDAY, JANUARY 28
Conference Program Print | View meeting in 12 hr (am/pm) time
The meeting will begin on Monday, January 25 with . Conference events conclude on Thursday, January 28 with a closing plenary session from 12:00 to , followed by . We recommend return travel on Friday, January 29 in order to fully experience the meeting.
MONDAY, JANUARY 25
08:00—08:40
Welcoming Remarks and Keynote Address (8am Denver/Mountain Time Start)
*
Diane Mathis,
Harvard Medical School, USA
Session Chair
Session Chair
*
Marc Y. Donath,
University Hospital Basel, Switzerland
Session Chair
Session Chair
Bruce M. Spiegelman,
Dana-Farber Cancer Institute, USA
Adipose Inflammation: Many Players and Many Regulatory Functions
Adipose Inflammation: Many Players and Many Regulatory Functions
08:00—08:40
Welcoming Remarks and Keynote Address (8am Denver/Mountain Time Start)
*
Erik A. Sahai,
Francis Crick Institute, UK
Session Chair
Session Chair
*
Alec Kimmelman,
New York University Langone Medical Center, USA
Session Chair
Session Chair
*
Johanna A. Joyce,
University of Lausanne, Switzerland
Session Chair
Session Chair
Matthew G. Vander Heiden,
Massachusetts Institute of Technology, USA
Impact of Nutrient Availability on Cancer Metabolic Dependencies
Impact of Nutrient Availability on Cancer Metabolic Dependencies
08:40—10:10
Immunometabolism: The Metabolic View (8:40am Denver/Mountain Time Start)
*
Janelle S. Ayres,
The Salk Institute for Biological Studies, USA
Session Chair
Session Chair
*
Diane Mathis,
Harvard Medical School, USA
Control of Metabolism by Immune Cells
Control of Metabolism by Immune Cells
Vishwa Deep Dixit,
Yale University, USA
Immunometabolic Regulation of Aging
Immunometabolic Regulation of Aging
Ana Domingos,
University of Oxford, UK
Neuroimmunometabolism
Neuroimmunometabolism
Emily Vohralik,
UNSW Sydney, Australia
Short Talk: Regulation of Adipose Tissue Beiging by Krüppel-Like Factor 3 (KLF3) and Eosinophils
Short Talk: Regulation of Adipose Tissue Beiging by Krüppel-Like Factor 3 (KLF3) and Eosinophils
Coffee Break
08:40—10:15
Metabolic Effects on the Immune System (8:40am Denver/Mountain Time Start)
*
Erik A. Sahai,
Francis Crick Institute, UK
Session Chair
Session Chair
*
M. Celeste Simon,
University of Pennsylvania, USA
Metabolic Symbioses in Stressful Tumor Microenvironments
Metabolic Symbioses in Stressful Tumor Microenvironments
Costas A. Lyssiotis,
University of Michigan, USA
Metabolic Networks in the Tumor Microenvironment
Metabolic Networks in the Tumor Microenvironment
Siva Karthik Varanasi,
The Salk Institute for Biological Studies, USA
Short Talk: Tumor Metabolism Shapes Antigen Presentation and Adaptive Immune Responses
Short Talk: Tumor Metabolism Shapes Antigen Presentation and Adaptive Immune Responses
Hilary A. Coller,
University of California, Los Angeles, USA
Short Talk: Cancer-Associated Stroma Requires Autophagy to Promote Tumor Growth by Maintaining Melanoma-Associated Fibroblasts and Suppressing Th1-Type Immune Responses
Short Talk: Cancer-Associated Stroma Requires Autophagy to Promote Tumor Growth by Maintaining Melanoma-Associated Fibroblasts and Suppressing Th1-Type Immune Responses
Eline C. Brombacher,
LUMC, Netherlands
Short Talk: Activation of Nutrient-Sensor AMPK in Tumor-Associated Dendritic Cells Promotes Tolerogenic Responses and Compromises the Anti-Tumor Immunity
Short Talk: Activation of Nutrient-Sensor AMPK in Tumor-Associated Dendritic Cells Promotes Tolerogenic Responses and Compromises the Anti-Tumor Immunity
Coffee Break
10:45—12:15
The CNS Microenvironment (10:45am Denver/Mountain Time Start)
*
Alec Kimmelman,
New York University Langone Medical Center, USA
Session Chair
Session Chair
Frank Winkler,
University Hospital Heidelberg, Germany
Brain Tumor Cells Interconnect to a Functional and Resistant Network
Brain Tumor Cells Interconnect to a Functional and Resistant Network
Johanna A. Joyce,
University of Lausanne, Switzerland
Charting the Immune Landscape across Diverse Brain Cancers
Charting the Immune Landscape across Diverse Brain Cancers
*
Michael E. Pacold,
New York University Medical Center, USA
Brain Metastasis Adaptation to the Metabolic Niche of the Central Nervous System
Brain Metastasis Adaptation to the Metabolic Niche of the Central Nervous System
Gino Ferraro,
Harvard Medical School, Massachusetts General Hospital, USA
Short Talk: Fatty Acid Synthesis is Required for Breast Cancer Brain Metastasis
Short Talk: Fatty Acid Synthesis is Required for Breast Cancer Brain Metastasis
10:20—12:15
Immunometabolism: The Immunologist View (10:20am Denver/Mountain Time Start)
*
Vishwa Deep Dixit,
Yale University, USA
Session Chair
Session Chair
Christoph Hess,
University Hospital Basel/University of Cambridge, Switzerland
From Patient to Molecular Understanding of Immunometabolism
From Patient to Molecular Understanding of Immunometabolism
Luke A. J. O'Neill,
Trinity Biomedical Sciences Institute, Ireland
Krebs Cycle Repurposed for Cytokines
Krebs Cycle Repurposed for Cytokines
Janelle S. Ayres,
The Salk Institute for Biological Studies, USA
Metabolic Adaptations in Host-Microbe Interactions
Metabolic Adaptations in Host-Microbe Interactions
Katrin Andreasson,
Stanford University, USA
Short Talk: Metabolic Reprogramming of Myeloid Cells Reverses Cognitive Decline in Aging
Short Talk: Metabolic Reprogramming of Myeloid Cells Reverses Cognitive Decline in Aging
14:00—15:00
Meet the Editors (Joint) (2pm Denver/Mountain Time Start)
Ubaldo E. Martinez Outschoorn,
Thomas Jefferson University/Frontiers, USA
Stephanie Ailsa Houston,
Journal of Experimental Medicine, USA
Lise Roth,
European Molecular Biology Organization, Germany
Catarina Sacristán,
Cell Press, USA
08:00—09:30
Clinical Translation: Unmet Needs (8am Denver/Mountain Time Start)
*
Luke A. J. O'Neill,
Trinity Biomedical Sciences Institute, Ireland
Session Chair
Session Chair
*
Morris J. Birnbaum,
Retired Pfizer, Inc., USA
Session Chair
Session Chair
Marina Mesquida,
F. Hoffmann-La Roche Ltd, Switzerland
Anti-Inflammatory Treatment of Diabetic Eye Complications
Anti-Inflammatory Treatment of Diabetic Eye Complications
Marc Y. Donath,
University Hospital Basel, Switzerland
IL-1beta in Physiology and Treatment of Metabolic Diseases
IL-1beta in Physiology and Treatment of Metabolic Diseases
Tom Thuren,
Novartis Pharmaceuticals, USA
Requirement to Implement Anti-Inflammatory Treatment of Cardiometabolic Diseases
Requirement to Implement Anti-Inflammatory Treatment of Cardiometabolic Diseases
Elena Carcarino,
INSERM, France
Short Talk: Epigenomic Regulation of IL-1B Enhancers in Type 2 Diabetes
Short Talk: Epigenomic Regulation of IL-1B Enhancers in Type 2 Diabetes
Coffee Break
08:00—09:55
Metastatic Colonisation (8am Denver/Mountain Time Start)
*
Johanna A. Joyce,
University of Lausanne, Switzerland
Session Chair
Session Chair
*
Ruth Scherz-Shouval,
Weizmann Institute of Science, Israel
Session Chair
Session Chair
Sarah-Maria Fendt,
VIB-KU Leuven, Belgium
Metabolic Rewiring Boosting Metastasis Formation
Metabolic Rewiring Boosting Metastasis Formation
Mikala Egeblad,
Cold Spring Harbor Laboratory, USA
Activating a Collaborative Innate-Adaptive Immune Response to Restrain Metastasis
Activating a Collaborative Innate-Adaptive Immune Response to Restrain Metastasis
Matthew F. Krummel,
University of California, San Francisco, USA
Imaging the Tumor Microenvironment in Five Dimensions
Imaging the Tumor Microenvironment in Five Dimensions
Heather Christofk,
University of California, Los Angeles, USA
Targeting Cancer Asparagine Dependence
Targeting Cancer Asparagine Dependence
Kevin B. Walsh,
Genentech, USA
Short Talk: VEGF Blockade Augments CD8+ T Cell Activity by Amplifying Tumor Hypoxia
Short Talk: VEGF Blockade Augments CD8+ T Cell Activity by Amplifying Tumor Hypoxia
Coffee Break
10:25—12:15
The Pancreatic Tumor Microenvironment (10:25am Denver/Mountain Time Start)
*
Johanna A. Joyce,
University of Lausanne, Switzerland
Session Chair
Session Chair
Lewis C. Cantley,
Dana Farber Cancer Institute, USA
Insulin and Cancer
Insulin and Cancer
*
Mara H. Sherman,
Memorial Sloan Kettering Cancer Center, USA
Mechanisms and Consequences of Pancreatic Cancer Stromal Evolution
Mechanisms and Consequences of Pancreatic Cancer Stromal Evolution
Andrea M. Amitrano,
University of Rochester School of Medicine & Dentistry, USA
Short Talk: Regulation of CD8+ T Cell Metabolism and Migration with Optogenetics
Short Talk: Regulation of CD8+ T Cell Metabolism and Migration with Optogenetics
Patricia Altea Manzano,
VIB-KU Leuven Center for Cancer Biology, Belgium
[NOT AVAILABLE ON DEMAND] Short Talk: Environmental Fatty Acids Support Changes in Histone Acetylation that Promote Breast Cancer Metastasis
[NOT AVAILABLE ON DEMAND] Short Talk: Environmental Fatty Acids Support Changes in Histone Acetylation that Promote Breast Cancer Metastasis
Felix Hartmann,
Stanford University, USA
Short Talk: Single-Cell Metabolic Regulome Profiling of Human Immune Cells in the Tumor Microenvironment
Short Talk: Single-Cell Metabolic Regulome Profiling of Human Immune Cells in the Tumor Microenvironment
Tanya Schild,
Weill Cornell Medicine, USA
Short Talk: NADK Regulation by Oncogenic KRAS Signaling is Essential for PDAC
Short Talk: NADK Regulation by Oncogenic KRAS Signaling is Essential for PDAC
10:00—11:45
Insulin Production and Action (10:00am Denver/Mountain Time Start)
*
Marc Y. Donath,
University Hospital Basel, Switzerland
Session Chair
Session Chair
Alan R. Saltiel,
University of California, San Diego, USA
Inflammatory Links Between Obesity and Energy Metabolism
Inflammatory Links Between Obesity and Energy Metabolism
Bruce Verchere,
University of British Columbia, Canada
Islet Amyloid Polypeptide and Islet Inflammation
Islet Amyloid Polypeptide and Islet Inflammation
*
Elise Dalmas,
INSERM, France
Innate Immunity in the Pancreatic Islet Niche
Innate Immunity in the Pancreatic Islet Niche
Feyza Engin,
University of Wisconsin-Madison, USA
Short Talk: Targeting Beta Cell Unfolded Protein Response in Type 1 Diabetes
Short Talk: Targeting Beta Cell Unfolded Protein Response in Type 1 Diabetes
Katia Monsorno,
University of Lausanne, Switzerland
Short Talk: Lactate Metabolism in the Control of Microglial Function
Short Talk: Lactate Metabolism in the Control of Microglial Function
12:00—13:00
Poster Session 1 (12pm Denver/Mountain Time Start)
13:00—14:00
Career Roundtable (Joint) (1pm Denver/Mountain Time Start)
Donita C. Brady,
University of Pennsylvania, USA
Matthew G. Vander Heiden,
Massachusetts Institute of Technology, USA
Tom Thuren,
Novartis Pharmaceuticals, USA
08:00—10:00
Adipose Tissues (8am Denver/Mountain Time Start)
*
Elise Dalmas,
INSERM, France
Session Chair
Session Chair
*
Bruce M. Spiegelman,
Dana-Farber Cancer Institute, USA
Session Chair
Session Chair
Rinke Stienstra,
Wageningen University and RadboudUMC, Netherlands
Obesity and Diabetes: An Immunometabolic Perspective
Obesity and Diabetes: An Immunometabolic Perspective
Paul Cohen,
Rockefeller University, USA
The Adipose Tissue Microenvironment in Health and Disease
The Adipose Tissue Microenvironment in Health and Disease
Jun Wu,
University of Michigan, USA
[NOT AVAILABLE ON DEMAND] Immune-Beige Adipocyte Communication
[NOT AVAILABLE ON DEMAND] Immune-Beige Adipocyte Communication
Inbar Shteinberg,
Tel Aviv University, Israel
Short Talk: Distinctive Effects of Alarmins S100A8 and S100A9 on Adaptive Thermogenesis
Short Talk: Distinctive Effects of Alarmins S100A8 and S100A9 on Adaptive Thermogenesis
Katelyn D. Miller,
Wistar Institute, USA
Short Talk: Inhibition of Acetate Metabolism Enhances Host Anti-Tumor Immunity
Short Talk: Inhibition of Acetate Metabolism Enhances Host Anti-Tumor Immunity
Pegah Poursharifi,
University of Montreal-CRCHUM, Canada
Short Talk: Suppression of ABHD6 Promotes Healthy Expansion of Adipose Tissue in Obesity
Short Talk: Suppression of ABHD6 Promotes Healthy Expansion of Adipose Tissue in Obesity
Coffee Break
08:00—09:40
Identifying the Metabolic Dependencies of Cancer Cells (8am Denver/Mountain Time Start)
*
Erik A. Sahai,
Francis Crick Institute, UK
Session Chair
Session Chair
Karen H. Vousden,
Francis Crick Institute, UK
[NOT AVAILABLE ON DEMAND] Metabolic Control of Invasion and Metastasis
[NOT AVAILABLE ON DEMAND] Metabolic Control of Invasion and Metastasis
Eileen P. White,
Rutgers Cancer Institute of New Jersey, USA
Autophagy and Systemic Metabolism
Autophagy and Systemic Metabolism
Navdeep S. Chandel,
Northwestern University, USA
Mitochondrial Regulation of Cancer
Mitochondrial Regulation of Cancer
*
Donita C. Brady,
University of Pennsylvania, USA
New Sides for an Old Coin: Copper as an Intracellular Mediator of Autophagy via ULK1/2 Kinase Signaling
New Sides for an Old Coin: Copper as an Intracellular Mediator of Autophagy via ULK1/2 Kinase Signaling
Coffee Break
10:10—12:10
Therapeutic Targeting of Metabolism and the TME (10:10am Denver/Mountain Time Start)
*
Erik A. Sahai,
Francis Crick Institute, UK
Session Chair
Session Chair
Shannon J. Turley,
Genentech, Inc., USA
Evolving Stromal-Immune Axis in Cancer Immunology and Immunotherapy
Evolving Stromal-Immune Axis in Cancer Immunology and Immunotherapy
*
Marcia C. Haigis,
Harvard Medical School, USA
Dissecting the Tumor-Immune Metabolic Crosstalk in the Tumor Microenvironment
Dissecting the Tumor-Immune Metabolic Crosstalk in the Tumor Microenvironment
Valerie M. Weaver,
University of California, San Francisco, USA
Interplay between Tissue Fibrosis, Metabolic Reprogramming and Inflammation in Tumor Evolution
Interplay between Tissue Fibrosis, Metabolic Reprogramming and Inflammation in Tumor Evolution
Natalya N. Pavlova,
Memorial Sloan Kettering Cancer Center, USA
Short Talk: Translation in Amino Acid-Poor Environments is Limited by tRNAGln Charging
Short Talk: Translation in Amino Acid-Poor Environments is Limited by tRNAGln Charging
Thomas Hanigan,
The Scripps Research Institute, USA
Short Talk: Small Molecule Inhibition of OXA1L Selectively Kills ZFHX3 Mutant NSCLC from Imbalanced Cytidine Pool Expansion
Short Talk: Small Molecule Inhibition of OXA1L Selectively Kills ZFHX3 Mutant NSCLC from Imbalanced Cytidine Pool Expansion
Arin Aurora,
University of Texas Southwestern Medical Center, USA
Short Talk: Metastasizing Melanoma Cells Exhibit Increased Dependence on the Pentose Phosphate Pathway to Manage Oxidative Stress
Short Talk: Metastasizing Melanoma Cells Exhibit Increased Dependence on the Pentose Phosphate Pathway to Manage Oxidative Stress
10:10—12:10
Liver (10:10am Denver/Mountain Time Start)
*
Gwendalyn J. Randolph,
Washington University, USA
Session Chair
Session Chair
*
Alan R. Saltiel,
University of California, San Diego, USA
Session Chair
Session Chair
Michael Karin,
University of California, San Diego, USA
Mitochondrial DNA Metabolism and IL-1 Mediated Inflammation
Mitochondrial DNA Metabolism and IL-1 Mediated Inflammation
Evanna Mills,
Dana-Farber Cancer Institute, USA
Thermogenic Fat as a Modifier of the Immune Response
Thermogenic Fat as a Modifier of the Immune Response
Morris J. Birnbaum,
Retired Pfizer, Inc., USA
Therapeutic Approaches for the Treatment of Non-Alcoholic Fatty Liver Disease
Therapeutic Approaches for the Treatment of Non-Alcoholic Fatty Liver Disease
Han Wang,
Ohio State University, Comprehensive Cancer Center, USA
Short Talk: Neutrophil Extracellular Traps Promote the Differentiation of Tregs through Metabolic Reprogramming to Impair Cancer Immunosurveillance in NASH Liver
Short Talk: Neutrophil Extracellular Traps Promote the Differentiation of Tregs through Metabolic Reprogramming to Impair Cancer Immunosurveillance in NASH Liver
Sabine Daemen,
Washington University in St. Louis, USA
Short Talk: Recruited Monocyte-Derived Macrophages Regulate Hepatic Crown-Like Structure Formation and Liver Fibrosis in NASH
Short Talk: Recruited Monocyte-Derived Macrophages Regulate Hepatic Crown-Like Structure Formation and Liver Fibrosis in NASH
Jin Young Huh,
Seoul National University, South Korea
Short Talk: Tank-Binding Kinase 1 Regulates the Localization of acyl-CoA synthetase ACSL1 to Control Hepatic Fatty Acid Oxidation
Short Talk: Tank-Binding Kinase 1 Regulates the Localization of acyl-CoA synthetase ACSL1 to Control Hepatic Fatty Acid Oxidation
08:00—09:45
Muscle/Cardiovascular (8am Denver/Mountain Time Start)
*
Ana Domingos,
University of Oxford, UK
Session Chair
Session Chair
Helga Ellingsgaard,
Centre for Physical Activity Research, Copenhagen, Denmark
IL-6, a Physiological Regulator of Adipose Tissue Mass in Humans
IL-6, a Physiological Regulator of Adipose Tissue Mass in Humans
*
Mark A. Febbraio,
Monash Institute of Pharmaceutical Sciences, Australia
Treatment of Type 2 Diabetes and Age-Related Sarcopenia with the Designer Cytokine IC7Fc
Treatment of Type 2 Diabetes and Age-Related Sarcopenia with the Designer Cytokine IC7Fc
Amy J. Wagers,
Harvard University, USA
Stem Cell Metabolism and Muscle Regeneration
Stem Cell Metabolism and Muscle Regeneration
Shuang Zhang,
Harvard Medical School/Massachusetts General Hospital, USA
Short Talk: Bone Marrow Adipocytes Fuel Fatty Acid Metabolism Directed Myelopoiesis after Myocardial Infarction
Short Talk: Bone Marrow Adipocytes Fuel Fatty Acid Metabolism Directed Myelopoiesis after Myocardial Infarction
Dina Chokr,
INSERM, Centre de Recherche des Cordeliers, France
Short Talk: Impact of Histone Lysine Demethylase 6B on Adipose Tissue Macrophage Plasticity
Short Talk: Impact of Histone Lysine Demethylase 6B on Adipose Tissue Macrophage Plasticity
Coffee Break
08:00—09:45
Intercellular Signaling Networks in the TME (8am Denver/Mountain Time Start)
*
Karin E. de Visser,
Netherlands Cancer Institute, Netherlands
How the Genetic Makeup of Breast Cancer Shapes the Immune Landscape
How the Genetic Makeup of Breast Cancer Shapes the Immune Landscape
*
Erik A. Sahai,
Francis Crick Institute, UK
Towards a Holistic Understanding of Tumor Architecture
Towards a Holistic Understanding of Tumor Architecture
Ruth Scherz-Shouval,
Weizmann Institute of Science, Israel
Transcriptional Heterogeneity of Cancer-Associated Fibroblasts in the Tumor Microenvironment
Transcriptional Heterogeneity of Cancer-Associated Fibroblasts in the Tumor Microenvironment
Hannah Bell,
University of Michigan, USA
Short Talk: Microbiota Metabolic Exchange Is Critical for Colorectal Cancer Redox Homeostasis and Growth
Short Talk: Microbiota Metabolic Exchange Is Critical for Colorectal Cancer Redox Homeostasis and Growth
Christina Schmidt,
University of Cambridge, UK
Short Talk: TRACER, a 3D-Model to Study the Influence of the Microenvironment on the Metabolic Profile of Fumarate Hydratase-Deficient Cells
Short Talk: TRACER, a 3D-Model to Study the Influence of the Microenvironment on the Metabolic Profile of Fumarate Hydratase-Deficient Cells
Coffee Break
10:15—12:00
Metabolic Compartmentalisation (10:15am Denver/Mountain Time Start)
*
Ralph J. DeBerardinis,
University of Texas Southwestern Medical Center, USA
Compartmentalized Metabolism in Physiological States of Growth
Compartmentalized Metabolism in Physiological States of Growth
Erika L. Pearce,
Johns Hopkins University, USA
Metabolic Regulation of the Immune Metabolism
Metabolic Regulation of the Immune Metabolism
*
Alec Kimmelman,
New York University Langone Medical Center, USA
Metabolic Crosstalk in PDAC
Metabolic Crosstalk in PDAC
Fabricio Loayza-Puch,
German Cancer Research Center, Germany
Short Talk: Dual Ribosome Profiling Uncovers Metabolic Limitations in Distinct Cellular Populations of the Tumor Microenvironment
Short Talk: Dual Ribosome Profiling Uncovers Metabolic Limitations in Distinct Cellular Populations of the Tumor Microenvironment
Marina Fukano,
Rosalind & Morris Goodman Cancer Research Centre, McGill University, Canada
[NOT AVAILABLE ON DEMAND] Short Talk: Investigating Intra-Tumour Metabolic Heterogeneity in Triple-Negative Breast Cancer
[NOT AVAILABLE ON DEMAND] Short Talk: Investigating Intra-Tumour Metabolic Heterogeneity in Triple-Negative Breast Cancer
12:00—12:10
Closing Remarks (12pm Denver/Mountain Time Start)
12:10—13:30
Networking Lounge (12:10pm Denver/Mountain Time Start)
10:05—11:50
Cardiovascular (10:05am Denver/Mountain Time Start)
*
Paul Cohen,
Rockefeller University, USA
Session Chair
Session Chair
*
Michael Karin,
University of California, San Diego, USA
Session Chair
Session Chair
Eicke Latz,
University of Bonn, Germany
Pharmacological Modulation of Cellular Metabolism Controls Macrophage Metabolism
Pharmacological Modulation of Cellular Metabolism Controls Macrophage Metabolism
Gwendalyn J. Randolph,
Washington University, USA
Immunity and Lipoprotein Trafficking
Immunity and Lipoprotein Trafficking
Matthias Nahrendorf,
Massachusetts General Hospital, USA
Post-MI Emergency Hematopoiesis and Metabolism
Post-MI Emergency Hematopoiesis and Metabolism
Jan Van den Bossche,
Amsterdam UMC VUmc, Netherlands
Short Talk: Macrophage ATP Citrate Lyase Deficiency Stabilizes Atherosclerotic Plaques
Short Talk: Macrophage ATP Citrate Lyase Deficiency Stabilizes Atherosclerotic Plaques
Enyuan Cao,
Monash University, Australia
Short Talk: Mesenteric Lymphatic Dysfunction Promotes Insulin Resistance and Represents a Potential Novel Treatment Target in Obesity
Short Talk: Mesenteric Lymphatic Dysfunction Promotes Insulin Resistance and Represents a Potential Novel Treatment Target in Obesity
11:50—12:00
Closing Remarks (11:50am Denver/Mountain Time Start)
12:00—13:30
Networking Lounge (12pm Denver/Mountain Time Start)
*Session Chair †Invited, not yet responded.
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