Keystone Symposia

This meeting took place in 2011

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Histone Code: Fact or Fiction? (A6)

Organizer(s) Karolin Luger, James Davie and Joanna Wysocka
January 10—15, 2011
Zermatt Resort & Spa - Utah • Midway, UT USA
Abstract Deadline: Sep 16, 2010
Late Abstract Deadline: Oct 13, 2010
Scholarship Deadline: Sep 16, 2010
Early Registration Deadline: Nov 10, 2010

Sponsored by Pfizer Inc.

Summary of Meeting:
It has become customary to refer to posttranslational histone modifications in all contexts as “epigenetic”, and to refer to a histone ‘code’. In certain contexts, histone modifications contribute to the epigenetic maintenance, whereas in others, they don’t. Similarly, some of the phenomena attributed to the posttranslational modification of histones do not fall into the strict definition of a ‘histone code’. This meeting strives to bring together scientists from different ‘camps’, to illuminate the effects of posttranslational modifications from many viewpoints. The emphasis here is on the effect of PTMs on the structure and readout of the genome, and less on the enzymatic activities and their regulation. Speakers will be encouraged to engage in rigorous discussion, as is obvious in the format for the opening and closing session which will be held in discussion format. In particular, we plan to • Investigate how histone modifications participate in the maintenance of epigenetic information • Elaborate on recent findings that epigenetic states are likely conveyed as a dynamic equilibrium of opposing modifying activities that involves feedback loops, and talk about ‘epigenetic memory’ • How do histone modifications affect nucleosome / chromatin structure and stability / interaction with chromatin architectural proteins? • Discuss the responsiveness of the epigenetic process, and the 3-D interplay in the nuclear environment that ultimately decides which gene will be fired up. • Have a workshop highlighting newest approaches / technologies to study histone modification states. • Have a final round table discussion to perhaps re-define and tighten up terminology, and to consolidate viewpoints where possible.

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Scholarship / Award Information

Scholarship Deadline: September 16, 2010 (11:59 PM US Mountain Standard Time)
*All deadlines end at 11:59 PM US Mountain Standard Time
NOTE: Please use the button above to Apply for a Scholarship


Keystone Symposia is offering scholarships of up to 1,200 USD to Students and Postdoctoral fellows. These scholarships are to be used to help defray the expenses associated with conference attendance, including airfare (restrictions may apply based on funding source), ground transportation, lodging costs, and a portion of meeting registration. Receipts will be required to receive reimbursement.

Abstracts submitted for poster presentation will be used as the basis for awarding the scholarships. Scholarship recipients will be selected based on the quality of science of the abstract and the relevance of the abstract to the conference topic. Only one application per abstract is accepted. Only one award per lab will be allocated.


To be eligible for a scholarship, you must be:

A graduate student or postdoctoral fellow currently enrolled in an academic institute at the start of the meeting for which you are applying. Note: a graduate student is defined as a student who is studying for a higher degree at an academic institution. A postdoctoral fellow is defined as an individual with a Ph.D., M.D., or DVM degree who is engaged in a temporary period of mentored research and/or scholarly training for the purpose of acquiring the professional skills needed to pursue their desired career path, and is within 6 years of these degrees.

Review Criteria

Criteria for Abstract Review:

  1. Relevance to the meeting topic
  2. Significance of the scientific question and results
  3. Style
    • Organization (e.g. the abstract has a clear beginning, middle and end)
    • Grammar and spelling
  4. Clarity of scientific presentations
    • Clear question or hypothesis
    • Sufficient background
    • The experimental approach and rationale for the approach are clear
    • The results are clearly presented
    • The interpretation and conclusions are reasonable and logical

Application Process

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