Keystone Symposia

This meeting took place in 2012

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Ubiquitin Signaling (X2)

Organizer(s) Ivan Dikic and Raymond J. Deshaies
March 18—23, 2012
Whistler Conference Centre • Whistler, BC Canada
Abstract Deadline: Nov 16, 2011
Late Abstract Deadline: Dec 20, 2011
Scholarship Deadline: Nov 16, 2011
Early Registration Deadline: Jan 18, 2012

Supported by the Directors' Fund

Summary of Meeting:
Post-translational modifications of cellular proteins by ubiquitin and ubiquitin-like modifiers regulate a variety of functions in the cell. A crucial aspect of signaling through ubiquitin and Ubls is the presence of modular binding domains that recognize particular types of ubiquitin signals. Such molecular coupling creates an attractive “decoding” mechanism for responding to alterations in the cellular microenvironment and regulating physiological and pathophysiological conditions. In this meeting, we will discuss the major challenges in the field including detection of endogenous ubiquitination events, functional aspects of novel types of ubiquitin chains and their recognition by selective binding domains, and high-throughput technologies for comprehensive analysis of Ub modifications. The intersection between the deregulated ubiquitin signaling, pathogenesis of human diseases and therapies targeting the Ub system will be explored. The program offers a possibility for young scientists to present their own work and engage in discussions on the emerging topics in the field. Opportunities for interdisciplinary interactions will be significantly enhanced by the concurrent meeting on NF-kB Signaling and Biology: From Bench to Bedside, which will share a keynote address and three plenary sessions with this meeting.

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Keystone Symposia Future of Science Fund Scholarship Recipients

Almut Dufner
University Clinic Freiburg, Germany

Kyeorda Lotorya Kemp
Northwestern University, USA

Yu Kigoshi
University of Tsukuba, Japan

James A. Nathan
Cambridge Institute for Medical Research, UK

National Institute of General Medical Sciences (NIGMS) Ancillary Training Program Scholarship Recipients

Joseph R. Chaney
Purdue University, USA