Keystone Symposia

This meeting took place in 2013


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HIV Vaccines (X5)

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HIV Vaccines (X2)


Organizer(s) Georgia D. Tomaras, Quentin J. Sattentau and Barbara L. Shacklett
February 10—15, 2013
Keystone Resort • Keystone, CO USA
Abstract Deadline: Oct 10, 2012
Late Abstract Deadline: Nov 12, 2012
Scholarship Deadline: Oct 10, 2012
Early Registration Deadline: Dec 10, 2012

Sponsored by Gilead Sciences, Inc. Part of the Keystone Symposia Global Health Series, supported by the Bill & Melinda Gates Foundation.


Summary of Meeting:
Recent data in both humans and non-human primates suggest that a clinically useful HIV-1 vaccine is possible and that the use of therapeutic interventions can be an efficacious prevention strategy. The path forward will require a detailed understanding of the correlates of protection to HIV-1/SIV and the development of better immunogens to induce specific and long lasting immunity. Moreover, the role of vaccine elicited immune responses to prevent the initial stages of HIV-1 infection at mucosal sites will be critical toward understanding protective immunity. Scientific expertise from vaccine trials and studies of long term immunity will help inform decisions in the path to the induction of immunity by an HIV-1 vaccine. Furthermore, a better understanding of how to target an efficacious vaccine in diverse populations will require more detailed studies of host genetics, innate immune responses, the effect of therapeutic interventions and other host factors (that can affect the development of robust immune responses and/or the analysis of HIV-1 vaccine trials. At this meeting, leading experts from both within and outside the HIV field will present findings from recent advances in human and non-human primate trials on immune mechanisms of protection as well as implementation of efficacious vaccines and other preventative strategies in diverse populations. Opportunities for interdisciplinary interactions will be significantly enhanced by the concurrent meeting on B Cell Development and Function – which will share a keynote session and two plenary sessions with this meeting. This pairing is explicitly designed to enhance opportunities for exchanges between researchers who do not typically interact. In this regard, it must be emphasized that a major roadblock in our efforts to generate a successful HIV vaccine relates to our limited knowledge of the B cell subsets and signals required for the durable production of protective class-switched HIV-1 neutralizing and inhibitory antibodies systemically and at mucosal sites.

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Scholarships/Awards


Keystone Symposia Future of Science Fund Scholarship Recipients


Genevieve Fouda
Duke University Medical Center, USA

Tynisha Thomas
Albert Einstein College of Medicine, USA

National Institute of Allergy and Infectious Diseases (NIAID) Scholarship Recipients


Matthew W. Breed
Tulane National Primate Research Center, USA

Robert Buckheit III
Johns Hopkins University, USA

Esther F. Gijsbers
Academic Medical Center, University of Amsterdam, Netherlands

Ariel Halper-Stromberg
Rockefeller University, USA

Kristin Hollister
Indiana University School of Medicine, USA

Zhidong Hu
Shanghai Public Health Clinical Center Affiliated to Fudan University, China

Maryse Peressin
Institute of Virology, France

Rujun Song
McGill University Health Center RI, Montreal General Hospital, Canada

Office of AIDS Research, NIH Scholarship Recipients


Tad M. Davenport
University of Washington, USA

Katie J. Doores
The Scripps Research Institute, USA

Samra Elser
University of Pennsylvania, USA

Leslie Goo
NIAID, National Institutes of Health, USA

Jung Joo Hong
KRIBB, South Korea

Maryam Imam
International Centre for Genetic Engineering and Biotechnology, India

Alexander Kliche
, Germany

Elise Landais
International AIDS Vaccine Initiative, USA

Yue Li
University of Nebraska-Lincoln, USA

Frank Liang
Karolinska Institutet, Sweden

Olga Malykhina
Northwestern University, USA

Sean P. McBurney
Oregon Health Sciences University, USA

Andrew McGuire
Fred Hutchinson Cancer Research Center, USA

Takushi Nomura
National Institute of Infectious Diseases, Japan

Cheila Rocha
Faculdade de Farmácia da Universidade de Lisboa, Portugal

Kristina Rothaeusler
California National Primate Research Center, USA

Torben Schiffner
The Scripps Research Institute, USA

Humberto Valenzuela Ponce
Instituto Nacional de Enfermedades Respiratorias, Mexico

Danushka K. Wijesundara
John Curtin School of Medical Research, Australia

Keystone Symposia Global Health Travel Award Recipients, funded by the Bill & Melinda Gates Foundation


Obakpororo Ejiro Agbagwa
University of Port Harcourt, Nigeria

Oluwafemi David Ajayi
ABUAD Multi-System Hospital, Nigeria

Mary Adejumoke Bisi-Johnson
Obafemi Awolowo University, Nigeria

Jeffrey R. Dorfman
International Centre for Genetic Engineering and Biotechnology, South Africa

Samia Ahmed Kamal
Animal Health Research Institute, Egypt

Anne Kapaata
Uganda Virus Research Institute/Medical Research Council, Uganda

Elvis Banboye Kidzeru
University of Cape Town, South Africa

Rajesh Kumar
All India Institute of Medical Sciences, India

Jaclyn Kelly Mann
University of KwaZulu Natal, South Africa

Laura Newberry
College of Medicine Malawi/ Queen Elizabeth Central Hospital, Malawi

Phillip O. Okerentugba
University of Port Harcourt, Nigeria

Blessing Jachinma Okonko
Ebonyi State University, Nigeria

Susan Pereira Ribeiro
Case Western Reserve University, USA

Cathrine Scheepers
University of the Witwatersrand and the NICD, South Africa

Daniel James Sheward
University of Cape Town, South Africa

Augustine Okechukwu Udeze
University of Ilorin, Nigeria