Keystone Symposia

This meeting took place in 2013

Here are the related meetings in 2020:
Microbiome: Therapeutic Implications (T1)

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The Gut Microbiome: The Effector/Regulatory Immune Network (B3)

Organizer(s) Lloyd H. Kasper, Javier Ochoa-Repáraz and Sarkis K. Mazmanian
February 10—15, 2013
Sagebrush Inn & Suites • Taos, NM USA
Abstract Deadline: Oct 9, 2012
Late Abstract Deadline: Nov 8, 2012
Scholarship Deadline: Oct 9, 2012
Early Registration Deadline: Dec 5, 2012

Sponsored by Boehringer Ingelheim Pharmaceuticals, Inc.

Summary of Meeting:
The mammalian GI track harbors a complex assemblage of microbial organisms that are essential for the development of the immune system. Alterations of the gut microbiota may lead to immune dysregulation both in the gut and in distal effector sites leading to the development of autoimmune disease. This meeting will focus on the role of the microbiota in balancing the effector and regulatory response leading to immune homeostasis. Recent findings suggest that altering certain bacterial populations present in the gut can lead to an inflammatory state associated with Th1/Th17 polarization. In contrast, other commensal bacteria and their antigenic products, when presented in the correct context, are regulatory and protect against inflammation. Particular emphasis will be placed on the biologic dynamics of the microbiota, the interaction with APC, modulation of the regulatory network and the immunologic consequences on experimental and human autoimmune conditions such as IBD, CNS demyelination and RA. The practical application of these novel interactions between the host and gut microbiota may lead to the identification of new therapeutics and novel insights into the mechanisms of human autoimmunity. The opportunity to assemble basic scientists in bacteriology and mucosal immunology with clinicians to explore this rapidly expanding arena is unique as there have been no previous organized meetings to meet this need. How the gut microbiome guides effector and regulatory immune functions will provide new pathways for the development of novel therapeutic targets.

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Crohn's & Colitis Foundation of America Scholarship Recipients

Mark Bazett
Qu Biologics Inc., Canada

Kirsty Brown
University of British Columbia, Canada

Duy M. Dinh
Tufts Medical Center, USA

Taylor J. Feehley
University of Chicago, USA

Peera Hemarajata
Baylor College of Medicine, USA

Karishma Kamdar
University of Southern California, USA

Katherine Nutsch
Washington University in St. Louis, USA

Vaibhav Upadhyay
University of Chicago, USA

First Time Meeting Travel Award Recipients

Marcus Jones
Regeneron, USA

National Institute of General Medical Sciences (NIGMS) Ancillary Training Program Scholarship Recipients

Catherine Saenz
University of Connecticut, USA

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)/National Institute on Aging (NIA) Scholarship Recipients

Suzanne Devkota
Cedars-Sinai Medical Center, USA

Elaine Y. Hsiao
University of California, Los Angeles, USA

Nobuhiko Kamada
University of Michigan, USA