Keystone Symposia

This meeting took place in 2014

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Plant Signaling: Dynamic Properties (B1)

Organizer(s) Ottoline Leyser, Junko Kyozuka and Pamela C. Ronald
February 5—10, 2014
Beaver Run Resort • Breckenridge, CO USA
Discounted Abstract Deadline: Oct 15, 2013
Abstract Deadline: Nov 7, 2013
Scholarship Deadline: Oct 15, 2013
Discounted Registration Deadline: Dec 5, 2013

Sponsored by Monsanto Company

Summary of Meeting:
In recent years, rapid progress has been made in elucidating the molecular events underlying perception of extracellular signals and their transduction to regulate specific responses. These advances in understanding make it possible to consider the emergent behavior of signaling cascades. In each signaling system, the configuration and dynamics of the underlying molecular interactions deliver specific properties linking the signal to its response. For example there could be a graded response to the level of signal or a tight threshold below which there is no response, and above which there is a maximal response. It is these higher order properties that are functionally important for the success of the organism, and therefore they are the level at which natural selection has acted to shape each signaling system. It is now becoming possible to investigate these higher order properties and to understand how apparently different molecular level events can nonetheless produce signaling systems with similar properties. The incorporation of mathematical and computational modeling, and the adoption synthetic biology approaches are becoming important tools in this endeavor. To capture this exciting new synthesis, we propose a symposium focusing on the relationship between molecular level events and their higher order behavior, comparing the properties of signaling systems in diverse species, including non-plant examples. The symposium will be structured around common signaling features, such as switching between on and off states, the control of specificity, robustness in an unstable environment, and modulation of the sensitivity of the system by its activity or by external factors.

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National Science Foundation (NSF) Scholarship Recipients

Cawas Engineer
University of California, San Diego, USA

Rachel A. Hillmer
University of Minnesota, USA

Yan Liang
University of Missouri, USA

Jonathan R. Mayers
University of Wisconsin, USA

Edith Pierre-Jerome
Duke University, USA

Adriana Racolta
University of Arizona, USA

Juthamas Sae-Seaw
Stanford University, USA

Masatsugu Toyota
University of Wisconsin-Madison, USA

S. Phoebe Williams
Virginia Tech, USA