Keystone Symposia

This meeting took place in 2015

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Transcriptional and Epigenetic Influences on Stem Cell States (C9)

Organizer(s) Thomas P. Zwaka, Rudolf Jaenisch and Joanna Wysocka
March 23—28, 2015
Sheraton Steamboat Resort • Steamboat Springs, CO USA
Discounted Abstract Deadline: Nov 20, 2014
Abstract Deadline: Dec 19, 2014
Scholarship Deadline: Nov 20, 2014
Discounted Registration Deadline: Jan 22, 2015

Sponsored by Cell Research, Incyte Corporation, Journal of Molecular Cell Biology (JMCB) and Thermo Fisher Scientific Inc.

Summary of Meeting:
An ambitious goal in modern biology is to understand stem cell states. Although much is known about both the behavior of stem cells under various conditions and the molecular details of stem cell identity, there is a gap between these two bodies of knowledge. This meeting sets out to bridge this gap, with a focus on transcriptional and epigenetic control of stem cell function. Advances in these areas will enable us to devise new strategies not only to probe stem cell biology more deeply, but to model disease and to develop cellular therapies. This Keystone Symposia meeting will bring together researchers who strive to: 1) Describe transcriptional and epigenetic mechanisms that control specific stem cell behaviors; 2) Generate predictive models of stem cell fate determination; 3) Delineate the influence of cell cycle and signaling on stem cell state; and 4) Understand mechanisms governing cell fate change, including differentiation, reprogramming and transdifferentiation. Ultimately, the meeting will provide an opportunity to view copious empirical data on stem cell behavior through a molecular lens, and will bring together scientists from basic research fields, such as transcriptional control, chromatin modification and developmental biology, with disease-oriented and translational researchers who are developing therapies or modeling specific diseases.

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Keystone Symposia Future of Science Fund Scholarship Recipients

Sihem Cheloufi
MGH Cancer Centre and Centre for Regenerative Medicine, USA

Qiuyu Guo
University of Southern California, USA

Jaclyn J. Ho
Tenaya Therapeutics, USA

National Institute of General Medical Sciences (NIGMS) Ancillary Training Program Scholarship Recipients

Nicholas Gomez
University of North Carolina at Chapel Hill, USA

Antonia Navarro
Northwestern University, USA