Keystone Symposia

This meeting took place in 2015

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The Biological Code of Cell Signaling: A Tribute to Tony Pawson (F1)

Organizer(s) Tony Hunter and Rune Linding
January 11—16, 2015
Sheraton Steamboat Resort • Steamboat Springs, Colorado USA
Discounted Abstract Deadline: Sep 23, 2014
Abstract Deadline: Oct 15, 2014
Scholarship Deadline: Sep 23, 2014
Discounted Registration Deadline: Nov 12, 2014

Sponsored by the Journal of Molecular Cell Biology (JMCB), Regeneron Pharmaceuticals, Inc., Roche and Thermo Fisher Scientific Inc.

Summary of Meeting:
Prompted by the recent loss of one of the brightest stars in the life sciences, this Keystone Symposia meeting has been designed to honor the memory of Tony Pawson. The aim of the meeting is to provide a forward-looking symposium rooted in his prodigious scientific legacy. It constitutes a natural evolution of previous symposia he organized (such as the “Omics Meets Cell Biology” series and “The Evolution of Protein Phosphorylation”). As such, the scientific focus of the symposium is on the role of post-translational modifications (PTMs), modular protein domains and signaling networks as driving forces of human evolution and disease. The cellular world that Tony, with others, unlocked consists of dynamic protein networks created through the interactions of different protein modules, which together drive almost every intra- and inter-cellular decision process we know today. His most important contribution in this field is undoubtedly his discovery of the first protein interaction module, the SH2 domain, but numerous other interaction domains followed, leading to current investigations of how the dysregulation of these networks leads to new signaling states in disease that are critical for processes in, for instance, cancer, such as tumor progression, or drug resistance. The symposium thus spans the entire spectrum of fields that have been touched by Tony Pawson's prolific and inspiring research, while maintaining a strong forward-looking perspective.

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Keystone Symposia Future of Science Fund Scholarship Recipients

Itziar Pinilla-Macua
University of Pittsburgh, USA

Xiaolei Su
University of California, San Francisco, USA

The Elkes Foundation Scholarship Recipients

Jeanine F. Amacher
University of California, Berkeley, USA