Keystone Symposia

This meeting took place in 2016

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NF-kappaB and MAP Kinase Signaling in Inflammation (X4)

Organizer(s) Steven C. Ley, Zhijian 'James' Chen and Jenny P.Y. Ting
March 13—17, 2016
Whistler Conference Centre • Whistler, BC Canada
Discounted Abstract Deadline: Nov 11, 2015
Abstract Deadline: Dec 14, 2015
Scholarship Deadline: Nov 11, 2015
Discounted Registration Deadline: Jan 13, 2016

Sponsored by Genentech, Inc.

Joint Meeting: Ubiquitin Signaling (X3)

Summary of Meeting:
Dysregulated inflammatory responses underlie many major diseases, including arthritis, psoriasis, inflammatory bowel disease, atherosclerosis, metabolic disease and cancer. Consequently, there is considerable interest in the pharmaceutical industry in targeting the signaling pathways regulating inflammation as a potential therapeutic approach for treatment of these diseases. Gene expression during inflammatory responses is controlled by NF-kappaB transcription factors, IRF transcription factors and each of the major MAP kinase subtypes (ERK1/2, JNK and p38) in innate immune cells. This symposium will focus on the role of ubiquitination in regulating NF-kappaB and MAP kinase activation, and how NF-kappaB-dependent transcription is coordinated with IRF activation and MAP kinase signaling to control innate immunity. Progress in the therapeutic targeting of NF-kappaB and MAP kinase activation pathways for treatment of chronic inflammatory diseases and cancer will also be discussed.

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National Institute of Allergy and Infectious Diseases (NIAID) Scholarship Recipients

Anetta Svitorka Härtlova
University of Gothenburg, Sweden

Meri Kaustio
FIMM/University of Helsinki, Finland

Marina Kolesnichenko
Max Delbrueck Center for Molecular Medicine, Germany

Feng-Ming Yang
University of Texas MD Anderson Cancer Center, USA