Keystone Symposia

This meeting took place in 2018

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Selective Autophagy (Z2)

Organizer(s) Tamotsu Yoshimori, Hong Zhang and Anne Simonsen
April 22—26, 2018
Westin Miyako Kyoto • Kyoto, Japan
Discounted Abstract Deadline: Dec 19, 2017
Abstract Deadline: Jan 16, 2018
Scholarship Deadline: Dec 19, 2017
Discounted Registration Deadline: Feb 22, 2018

Sponsored by Nestlé Institute of Health Sciences

Summary of Meeting:
Autophagy is an evolutionarily conserved membrane trafficking process which delivers cargos from the cytoplasm to lysosomes and is critical for cellular homeostasis. Although autophagy has long been perceived as a non-selective pathway, researchers are increasingly realizing that autophagy can be highly selective. It has been shown that protein aggregates and damaged or superfluous organelles such as mitochondria, ER, peroxisomes, endosomes and lysosomes can be degraded by autophagy in a highly selective manner. Selective autophagy has also been shown to play an important role in controlling intracellular pathogens. Since several diseases have been linked to dysfunctional selective autophagy, researchers’ interest in the process is increasing. Altering the autophagy level has become a therapeutic target in various diseases, while the exact mechanisms of selective autophagy for each target remain to be uncovered. The primary goal of this program is to integrate and discuss the latest information about the underlying mechanisms of selective autophagy and its implication in diseases.

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Keystone Symposia Future of Science Fund Scholarship Recipients

Heeseon An
Harvard Medical School, USA

Laure-Anne Ligeon
University of Zürich – Institute of Experimental Immunology, Switzerland

Michael Joseph Munson
University of Oslo, Norway

Martina B. Wirth
Francis Crick Institute, UK

Lindsey Young
University of California, San Diego, USA