Keystone Symposia

This meeting took place in 2018

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The Resolution of Inflammation in Health and Disease (C6)

Organizer(s) Catherine Godson, Ira Tabas and Mauro Perretti
March 24—28, 2018
Royal Dublin Society • Dublin 4, Ireland
Discounted Abstract Deadline: Nov 29, 2017
Abstract Deadline: Dec 21, 2017
Scholarship Deadline: Nov 29, 2017
Discounted Registration Deadline: Jan 18, 2018

Organized in Collaboration with Science Foundation Ireland
Sponsored by Gilead Sciences, Inc.
This activity was supported by an educational grant from Celgene Corporation.

Summary of Meeting:
Inflammation and its resolution are critical to effective host defense and tissue homeostasis. There is a steady increase in the recognition that the effective resolution of inflammation is dynamically regulated through cellular responses to endogenously generated mediators. Ineffective resolution of inflammatory responses likely contributes to the pathogenesis of numerous prevalent conditions including atherosclerosis, arthritis and diabetes. Unresolved chronic inflammation may lead to fibrosis and eventual organ failure. Whereas anti-inflammatory therapeutic approaches are conventional, a growing consensus based on experimental data suggests that an alternative approach may be to mimic agonism of resolution. The aim of this meeting is to enhance our understanding of the molecular mechanisms which underpin the effective resolution of inflammation and how these may fail in aging and disease. Specifically, it seeks to: 1) Encourage dialog between those working in areas where the potential of mimicry of resolution of inflammation might play an under-appreciated role; 2) Consolidate data from diverse mediators that promote resolution; and 3) Contribute to the education and training of graduate students, fellows and faculty. These discussions will provide a multidisciplinary community with insight into physiologic processes underpinning resolution and potential mimicry of such processes for therapeutic gain in pathological conditions.

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Keystone Symposia Future of Science Fund Scholarship Recipients

Aoife Keogh
Royal College of Surgeons in Ireland, Ireland

Stephanie A. Legere
Dalhousie University, Canada

National Institute of Allergy and Infectious Diseases (NIAID) Scholarship Recipients

Douglas Brubaker
Massachusetts Institute of Technology, USA

Matt DeBerge
Northwestern University, USA

Michelle Amantéa Sugimoto
Universidade Federal de Minas Gerais, Brazil and Queen Mary University of London, UK

David G. Thomas
Columbia University, USA

Louise M. Topping
Queen Mary University of London, UK