Keystone Symposia

This meeting took place in 2020

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Gene Regulation: From Mechanisms to Disease (J3)

Organizer(s) Karen Adelman and Patrick Cramer
January 26—30, 2020
Keystone Resort • Keystone, CO USA
Discounted Abstract Deadline: Oct 1, 2019
Abstract Deadline: Oct 29, 2019
Scholarship Deadline: Oct 1, 2019
Discounted Registration Deadline: Nov 26, 2019

Sponsored by Moderna

Summary of Meeting:
Organismal development, homeostasis and healthy aging all rely on precise control of gene expression programs. Recent technological advances in structural biology, real-time imaging, and next generation sequencing have shed new light on decades-old questions about gene regulation, and we seek to highlight these advances. This meeting aims to bring together pioneers in cryoEM, single-cell microscopy, single cell sequencing and three-dimensional genome architecture, with leading experts in transcriptional regulation, to seed new collaborations and discoveries. This conference provides an ideal environment to foster interactions between transcriptional biologists and experts in single cell imaging and genomic approaches and spur conversations about how to interweave new techniques for structural biology with our growing appreciation that many critical interactions involve intrinsically disordered domains (which are by definition not well behaved in most structural approaches). Participants will attend sessions that critically evaluate the impact of genome organization on gene expression. The conference will also expose trainees to the best science possible and instill in them the enthusiasm we feel for the future of the field. Finally, pairing of this meeting with Cancer Epigenetics is ideal as the topics are inherently related. This allows our meeting to focus on underlying mechanisms and normal developmental systems, while enabling the audience to attend lectures in gene dysregulation in cancer. We plan two joint sessions to maximize interactions.

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National Human Genome Research Institute (NHGRI)/National Institute on Aging (NIA) Scholarship Recipients

Lexi Bounds
Duke University, USA

Wenqing Cai
Boston Children's Hospital, USA

Daisy Castillo-Guzman
University of California, Davis, USA

Giulia Cova
Max Planck Institute for Molecular Genetics, Germany

Tom Aharon Hait
Tel-Aviv University, Israel

Oliver Hendy
Research Institute of Molecular Pathology, Austria

Gabriella E. Martyn
University of New South Wales, Australia

Kirstin Meyer
University of California, San Francisco, USA

Dogancan Ozturan
Koc University, Turkey

Tengyao Song
National Jewish Health, USA

Hannah Weber
New York University School of Medicine, USA

Haoze Vincent Yu
University of Southern California, USA