Keystone Symposia

This meeting took place in 2020

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Stromal Cells in Immunity and Disease (Q5)

Organizer(s) Scott N. Mueller, Jason G. Cyster, Reina E. Mebius and Theresa T. Lu
February 19—23, 2020
Fairmont Empress Victoria / Victoria Conference Centre • Victoria, BC Canada
Discounted Abstract Deadline: Oct 17, 2019
Abstract Deadline: Nov 20, 2019
Scholarship Deadline: Oct 17, 2019
Discounted Registration Deadline: Dec 18, 2019

Sponsored by Merck & Co., Inc. and Roche

Summary of Meeting:
Non-hematopoietic stromal cells play important roles in many tissues, constructing tissue microenvironments, contributing to tissue repair, defense and immune responses. Within lymphoid organs, stromal cells organize and interact with leukocytes in an immunologically important manner. In addition to organizing T and B cell segregation and expressing lymphocyte survival factors, stromal cells support the migration and interactions between antigen presenting cells and naïve T and B cells during the initiation of immune responses and influence the outcome between tolerance and immunity. Stromal cells also play instrumental roles in coordinating immune responses in non-lymphoid tissues, in inflammatory and autoimmune diseases, and in chronic infection. For instance, stromal cell dysregulation has been seen in HIV infection and in cancer patients. Furthermore, stromal cells are being harnessed for therapeutic applications in several diseases, an area that holds great promise for improving human health. Our understanding of stromal cell populations and their contributions to innate and adaptive immunity as well as immunological diseases, cancer and vaccination has grown exponentially over the past few years. This emerging field has gained enormous momentum due to increasingly sophisticated tools to dissect the fundamental biology and clinical importance of this cellular compartment. This conference is being held jointly with Fibrosis and Tissue Repair: From Molecules and Mechanics to Therapeutic Approaches. This joint pairing will bring together basic and clinical scientists with interdisciplinary interests in stromal cell biology and disease treatment to discuss critical fundamental and translational advances. The goals of this conference are to showcase cutting-edge results and new directions in the field, stimulate interactions and provide a forum for trainees and new investigators to present their work and interact with leaders in the field.

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National Institute of Allergy and Infectious Diseases (NIAID) Scholarship Recipients

Ian Boothby
University of California, San Francisco, USA

Madeline Churchill
Oregon Health and Science University, USA

John Andrew Grout
Mount Sinai School of Medicine, USA

Laura Elisabeth Kähäri
University of Turku, Finland

Akira Takeda
University of Turku, Finland