This meeting took place in 2019
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The Malaria Endgame: Innovation in Therapeutics, Vector Control and Public Health Tools (G1)
Organizer(s) Thierry Diagana, Philip Welkhoff and Flaminia Catteruccia
October 30—November 2, 2019
Hilton Addis Ababa • Addis Ababa, Ethiopia
Discounted Abstract Deadline: Jul 9, 2019
Abstract Deadline: Jul 30, 2019
Scholarship Deadline: Jul 9, 2019
Discounted Registration Deadline: Aug 29, 2019
Part of the Keystone Symposia Global Health Series, supported by the Bill & Melinda Gates Foundation
Summary of Meeting:
Malaria is most prevalent in the tropical belt and many malaria endemic countries have now engaged in elimination programs. However, we are facing a public health crisis because we have lost many of the public health tools that enabled the progress we have made to date. Many drugs are useless in most areas and resistance is threatening even artemisinin-based combination therapy (ACT). Diagnostics, bed-nets and insecticides are also losing their effectiveness and the Plasmodium vivax (P. vivax) parasite is finding new ways to transmit in Duffy negative patients. At the same time, there are multiple emerging threats such as artemisinin drug resistance, the rise of P. vivax malaria prevalence, and the discovery of the parasite Plasmodium knowlesi (P. knowlesi) in humans. However, there are some interesting developments such as deploying older suboptimal drugs in new, innovative and targeted control approaches like seasonal malaria chemoprevention (SMC) or intermittent preventive treatment of pregnant women/ infants (PTi/p). There are new drugs on the horizon that have pharmacological properties compatible with single dose cures and could prove to be powerful tools in the fight against malaria. For example, mass drug administration has demonstrated substantial impact as an intervention for Plasmodium elimination. By learning from recent successes in malaria elimination, epidemiological models of malaria transmission can be updated, and the impact of new interventions will critically inform the malaria endgame strategy. The conference is organized around three themes: defeating resistance (both to drugs and to insecticides), leveraging data science to better understand disease transmission and innovation in vector control strategies. This program will assess the current threats and gaps in our malaria armamentarium to enable malaria elimination and discuss the emerging innovative approaches for antimalarial drug discovery and development.
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Malaria is most prevalent in the tropical belt and many malaria endemic countries have now engaged in elimination programs. However, we are facing a public health crisis because we have lost many of the public health tools that enabled the progress we have made to date. Many drugs are useless in most areas and resistance is threatening even artemisinin-based combination therapy (ACT). Diagnostics, bed-nets and insecticides are also losing their effectiveness and the Plasmodium vivax (P. vivax) parasite is finding new ways to transmit in Duffy negative patients. At the same time, there are multiple emerging threats such as artemisinin drug resistance, the rise of P. vivax malaria prevalence, and the discovery of the parasite Plasmodium knowlesi (P. knowlesi) in humans. However, there are some interesting developments such as deploying older suboptimal drugs in new, innovative and targeted control approaches like seasonal malaria chemoprevention (SMC) or intermittent preventive treatment of pregnant women/ infants (PTi/p). There are new drugs on the horizon that have pharmacological properties compatible with single dose cures and could prove to be powerful tools in the fight against malaria. For example, mass drug administration has demonstrated substantial impact as an intervention for Plasmodium elimination. By learning from recent successes in malaria elimination, epidemiological models of malaria transmission can be updated, and the impact of new interventions will critically inform the malaria endgame strategy. The conference is organized around three themes: defeating resistance (both to drugs and to insecticides), leveraging data science to better understand disease transmission and innovation in vector control strategies. This program will assess the current threats and gaps in our malaria armamentarium to enable malaria elimination and discuss the emerging innovative approaches for antimalarial drug discovery and development.
View Meeting Program
Scholarships/Awards
Keystone Symposia Future of Science Fund Scholarship Recipients
Donnie Mategula
Malawi-Liverpool-Wellcome Trust, Malawi
Kristine Werling
Harvard TH Chan School of Public Health, USA
Keystone Symposia Global Health Travel Award Recipients, funded by the Bill & Melinda Gates Foundation
Atul ..
National Institute of Malaria Research, India
Oyindamola Olajumoke Abiodun
College of Medicine, University of Ibadan, Nigeria
Rajeshwara Achur
Kuvempu University, India
George Olusegun Ademowo
Institute for Advanced Medical Research and Training, Nigeria
Funmilayo I. Deborah Afolayan
University of Ibadan, Nigeria
Koffi Mensah Ahadji-Dabla
University of Lomé, Togo
Uchenna Blessing Alozieuwa
Veritas University Abuja, Nigeria
Lilian Mbaisi Ang'ang'o
International Centre of Insect Physiology and Ecology, Kenya
Temesgen Ashine
Armauer Hansen Research Institute, Ethiopia
Shehu S. Awandu
Radboud University Medical Centre, Netherlands
Aissata Barry
Centre National de Recherche et de Formation sur le Paludisme, Burkina Faso
Felix Abekah Botchway
University of Ghana, Ghana
Stravensky Terence Boussougou Sambe
University of Tübingen, Gabon
Modupe Iretiola Builders
Bingham University, Nigeria
María Julia Dantur-Juri
CONICET-Fundación Miguel Lillo, Argentina
Tais N. de Sousa
René Rachou Institute, Brazil
Adilson José DePina
University Cheikh Anta Diop de Dakar - SénégalEarle, Cape Verde
Yehenew Asemamaw Ebstie
Addis Ababa University, Ethiopia
Deepika Fernando
University of Colombo, Sri Lanka
Abebe Fola
Purdue University, USA
Samuel N. Gachuhi
University of Cape Town, South Africa
Erika Francisca Garrido
Corporación Universitaria Remington, Colombia
Wakweya Chali Gerba
Armauer Hansen Research Institute/Radboudumc, Ethiopia
Lemu Golassa
Addis Ababa University, Ethiopia
Priya Gupta
National Institute of Malaria Research, India
Ouambo Fotso Herve
Chantal Biya Research Center, Cameroon
Stella Amarachi Ihim
University of Nigeria, Nsukka, Nigeria
Nalova Hermia Ikome
Institute of Medical Research and Medicinal Plant Studies, Cameroon
Maurice Ayamba Itoe
Harvard. T.H. Chan School of Public Health, USA
Nicole K. Jabo
University of Global Health Equity, Rwanda
Titilayo Omolara Johnson
University of Jos, Nigeria
Alebachew M. Kebede
Addis Ababa University, Ethiopia
Constance Mawunyo Korkor
University of Cape Town, South Africa
Seena Kumari
National Institute of Malaria Research, India
Raja Babu Singh Kushwah
Tata Institute for Genetics and Society, India
Dickson Mambwe
University of Cape Town, Department of Chemistry, South Africa
Sandeu Maurice Marcel
Centre for Research in Infectious Diseases, Cameroon
Agersew Alemu Mengist
University of Melbourne, Australia
Mokhitli Morake
University of Cape Town, South Africa
Sulaiman Adebayo Nassar
Ladoke Akintola University of Technology, Nigeria
Omonike Oluyemisi Ogbole
University of Ibadan, Nigeria
Ehimwenma Sheena Omoregie
University of Benin, Nigeria
Harris Onywera
University of Cape Town, South Africa
Bose Etaniamhe Orimadegun
University of Ibadan, College of Medicine, Nigeria
Razaki Ossè
Entomological Research Center, Benin
Nancy O. Quashie
Noguchi Memorial Institute for Medical Research, Ghana
Abeba Gebretsadik Reda
Ethiopian Public Health institute, Ethiopia
Komal Raj Rijal
Tribhuvan University, Nepal
Carola J. Salas
US Naval Medical Research Unit No. 6, Peru
Brian B. Tarimo
Ifakara Health Institute, Tanzania
Agatha Adaora Ugwu
University of Nigeria, Nigeria
Camilla Valente Pires
University of South Florida, USA
Tamirat Gebru Woldearegai
Institute of Tropical Medicine, Germany
Redemptah Ambogo Yeda
Walter Reed, Kenya
