Keystone Symposia

This meeting took place in 2001

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Molecular Clocks: Regulation of Circadian Behavioral Rhythms (D5)

Organizer(s) Michael W. Young, Ueli Schibler and Steven M. Reppert
March 20—25, 2001
Granlibakken Tahoe • Tahoe City, CA USA
Abstract Deadline: Nov 20, 2000
Late Abstract Deadline:
Scholarship Deadline:
Early Registration Deadline: Jan 19, 2001

Sponsored in part by the Director's Sponsor Fund

Summary of Meeting:
Several homologous clock genes regulate circadian behavioral rhythms throughout the animal kingdom. Most of these have been identified within the last 3-4 years by genetic screening in Drosophila and in the mouse. Clock genes encode interacting, autoregulatory proteins that promote self-sustaining molecular cycles of gene expression. These intracellular cycles depend on (1) transcriptional feedback loops, and (2) regulated RNA and protein turnover. Light resets these molecular clocks by altering the levels of certain clock gene products in specific patterns. Novel photoreceptors, cryptochromes, have been linked to these photic responses in some animals and in plants. While behaviors such as daily locomotor activity cycles in Drosophila or sleep/wake cycles in mice are regulated by defined neurons in the brain, very recent work has identified peripheral clocks that use the same set of genes to autonomously generate circadian molecular cycles in tissues as diverse as heart, liver, and retina. The past year has also witnessed the development of immortalized cell cultures as tools for examining circadian molecular rhythms. This Keystone Symposium is intended to provide a forum for communicating the results of this rapidly moving field in relation to all of the above areas, to increase our understanding of the mechanistic links connecting the molecular cycles to timed behavior, and to generate a medium for describing new approaches and concepts that have emerged in this area of molecular biology.

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Scholarship / Award Information

Scholarship Deadline: (11:59 PM US Mountain Standard Time)
*All deadlines end at 11:59 PM US Mountain Standard Time
NOTE: Please use the button above to Apply for a Scholarship


Keystone Symposia is offering scholarships of up to 1,200 USD to Students and Postdoctoral fellows. These scholarships are to be used to help defray the expenses associated with conference attendance, including airfare (restrictions may apply based on funding source), ground transportation, lodging costs, and a portion of meeting registration. Receipts will be required to receive reimbursement.

Abstracts submitted for poster presentation will be used as the basis for awarding the scholarships. Scholarship recipients will be selected based on the quality of science of the abstract and the relevance of the abstract to the conference topic. Only one application per abstract is accepted. Only one award per lab will be allocated.


To be eligible for a scholarship, you must be:

A graduate student or postdoctoral fellow currently enrolled in an academic institute at the start of the meeting for which you are applying. Note: a graduate student is defined as a student who is studying for a higher degree at an academic institution. A postdoctoral fellow is defined as an individual with a Ph.D., M.D., or DVM degree who is engaged in a temporary period of mentored research and/or scholarly training for the purpose of acquiring the professional skills needed to pursue their desired career path, and is within 6 years of these degrees.

Review Criteria

Criteria for Abstract Review:

  1. Relevance to the meeting topic
  2. Significance of the scientific question and results
  3. Style
    • Organization (e.g. the abstract has a clear beginning, middle and end)
    • Grammar and spelling
  4. Clarity of scientific presentations
    • Clear question or hypothesis
    • Sufficient background
    • The experimental approach and rationale for the approach are clear
    • The results are clearly presented
    • The interpretation and conclusions are reasonable and logical

Application Process

If you are eligible and wish to be considered for a scholarship, you should complete all of the following by the scholarship deadline for the meeting you wish to attend. It is recommended you begin these steps in advance of the deadline date to ensure completion.

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