Keystone Symposia

This meeting took place in 2001

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Cellular and Molecular Events in the Pathogenesis of Atherosclerosis (X2)

Organizer(s) Joseph L. Witztum, Linda K. Curtiss and Margaret Forney Prescott
April 24—29, 2001
Keystone Resort • Keystone, CO USA
Abstract Deadline: Dec 21, 2000
Late Abstract Deadline:
Scholarship Deadline:
Early Registration Deadline: Feb 24, 2001

Sponsored by Pfizer Global Research & Development

Summary of Meeting:
Although the role of hypercholesterolemia in the etiology of atherosclerosis is now established beyond doubt, understanding the complex molecular and cellular events involved in the artery wall are a prerequisite for an improved understanding of the pathogenesis of atherosclerosis, and for designing specific and improved interventions to prevent clinical disease. The atherosclerotic lesion has many properties of a chronic inflammatory disease, involving activated monocyte/macrophages, endothelial cells and smooth muscle cells, as well as humoral and cell-mediated immunological responses. Oxidative events play a central pathogenic role, both in the generation of modified lipids and proteins that mediate proinflammatory events, as well as in the formation of foam cells. Molecular events involved in regulation of key cellular events, including the role of nuclear receptors, that control cell trafficking into the artery, expression of cytokines, growth factors, metalloproteinases, and tissue factor, as well as regulation of cellular growth, migration, apoptosis and death are beginning to be addressed. In addition, recent experimental evidence indicates an important pathogenic role for angiogenesis. The proposed program will be held jointly with a Symposium dedicated to the role of angiogenesis and vascular biology, and should broaden the appeal of this meeting to investigators interested in these two interrelated topics. Specific sessions will be devoted to the role of oxidative stress, immunological mechanisms, macrophage biology, endothelial cell biology and scavenger receptors, as they apply to the pathogenesis of atherosclerosis. Joint plenary sessions will deal at a more fundamental level with nuclear receptors, cell trafficking and apoptosis/angiogenesis. This Keystone Symposium is intended to foster communication between investigators involved in understanding various mechanisms involved in vascular biology and atherosclerosis, and that new insights will be gained that will lead to novel and effective interventions to prevent this disease.

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Scholarship / Award Information

Scholarship Deadline: (11:59 PM US Mountain Standard Time)
*All deadlines end at 11:59 PM US Mountain Standard Time
NOTE: Please use the button above to Apply for a Scholarship


Keystone Symposia is offering scholarships of up to 1,200 USD to Students and Postdoctoral fellows. These scholarships are to be used to help defray the expenses associated with conference attendance, including airfare (restrictions may apply based on funding source), ground transportation, lodging costs, and a portion of meeting registration. Receipts will be required to receive reimbursement.

Abstracts submitted for poster presentation will be used as the basis for awarding the scholarships. Scholarship recipients will be selected based on the quality of science of the abstract and the relevance of the abstract to the conference topic. Only one application per abstract is accepted. Only one award per lab will be allocated.


To be eligible for a scholarship, you must be:

A graduate student or postdoctoral fellow currently enrolled in an academic institute at the start of the meeting for which you are applying. Note: a graduate student is defined as a student who is studying for a higher degree at an academic institution. A postdoctoral fellow is defined as an individual with a Ph.D., M.D., or DVM degree who is engaged in a temporary period of mentored research and/or scholarly training for the purpose of acquiring the professional skills needed to pursue their desired career path, and is within 6 years of these degrees.

Review Criteria

Criteria for Abstract Review:

  1. Relevance to the meeting topic
  2. Significance of the scientific question and results
  3. Style
    • Organization (e.g. the abstract has a clear beginning, middle and end)
    • Grammar and spelling
  4. Clarity of scientific presentations
    • Clear question or hypothesis
    • Sufficient background
    • The experimental approach and rationale for the approach are clear
    • The results are clearly presented
    • The interpretation and conclusions are reasonable and logical

Application Process

If you are eligible and wish to be considered for a scholarship, you should complete all of the following by the scholarship deadline for the meeting you wish to attend. It is recommended you begin these steps in advance of the deadline date to ensure completion.

Click here to start a scholarship application.

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Underrepresented Trainee Scholarships are also available...
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