Keystone Symposia

This meeting took place in 2005

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Molecular Biology of Cardiac Diseases and Regeneration (D2)

Organizer(s) Elizabeth McNally and Jonathan A. Epstein
April 3—8, 2005
Sheraton Steamboat Resort • Steamboat Springs, CO USA
Abstract Deadline: Dec 2, 2004
Late Abstract Deadline:
Scholarship Deadline:
Early Registration Deadline: Feb 3, 2005

Supported by The Director's Fund

Summary of Meeting:
Cardiovascular disease is the leading cause of morbidity and mortality in the United States. Myocardial infarction and congestive heart failure, together, account for the majority of cardiovascular disease. An underlying theme in both myocardial infarction and congestive heart failure is an insufficient number of properly functioning cardiomyocytes. Repairing defective cardiomyocytes and/or regenerating cardiomyocytes are important experimental means to improve heart function. To this end, stem cells from embryonic and adult sources have been increasingly explored as a means of restoring cardiac function. Vascular growth remains a significant concern since vascular supply is essential to the survival of regenerated cardiomyocytes. To establish a fully functioning cardiomyocyte requires a detailed understanding of cardiomyocyte differentiation as well as a pluripotent stem cell capable of achieving the cardiomyocyte developmental pathway. At the cellular level, cardiomyocyte dysfunction arises from ischemic insult, genetic or toxic metabolic defects. The broad etiology responsible for the dysfunctioning cardiomyocyte has not limited the identification of molecular pathways in common to these many different forms of heart failure. Defects of intracellular calcium homeostasis are a frequent issue in failing cardiomyocytes. Perturbations of calcium homeostasis directly affect sarcomere function and simultaneously render an altered signaling cascade. The goal of this meeting is twofold. We will discuss cellular and molecular pathways necessary for cardiac regeneration. This will include a discussion of stem cell choice as well as a full evaluation of current stem cell transplant programs with an emphasis on full integration and differentiation of the transplanted stem cell. The second major emphasis of the meeting will be to discuss the failing cardiomyocyte focused on the common and critical molecular pathways found in the diseased cardiomyocyte. These two broad areas overlap considerably since both approaches will be required to successfully repair a failed cardiomyocyte.

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Scholarship / Award Information

Scholarship Deadline: (11:59 PM US Mountain Standard Time)
*All deadlines end at 11:59 PM US Mountain Standard Time
NOTE: Please use the button above to Apply for a Scholarship


Keystone Symposia is offering scholarships of up to 1,200 USD to Students and Postdoctoral fellows. These scholarships are to be used to help defray the expenses associated with conference attendance, including airfare (restrictions may apply based on funding source), ground transportation, lodging costs, and a portion of meeting registration. Receipts will be required to receive reimbursement.

Abstracts submitted for poster presentation will be used as the basis for awarding the scholarships. Scholarship recipients will be selected based on the quality of science of the abstract and the relevance of the abstract to the conference topic. Only one application per abstract is accepted. Only one award per lab will be allocated.


To be eligible for a scholarship, you must be:

A graduate student or postdoctoral fellow currently enrolled in an academic institute at the start of the meeting for which you are applying. Note: a graduate student is defined as a student who is studying for a higher degree at an academic institution. A postdoctoral fellow is defined as an individual with a Ph.D., M.D., or DVM degree who is engaged in a temporary period of mentored research and/or scholarly training for the purpose of acquiring the professional skills needed to pursue their desired career path, and is within 6 years of these degrees.

Review Criteria

Criteria for Abstract Review:

  1. Relevance to the meeting topic
  2. Significance of the scientific question and results
  3. Style
    • Organization (e.g. the abstract has a clear beginning, middle and end)
    • Grammar and spelling
  4. Clarity of scientific presentations
    • Clear question or hypothesis
    • Sufficient background
    • The experimental approach and rationale for the approach are clear
    • The results are clearly presented
    • The interpretation and conclusions are reasonable and logical

Application Process

If you are eligible and wish to be considered for a scholarship, you should complete all of the following by the scholarship deadline for the meeting you wish to attend. It is recommended you begin these steps in advance of the deadline date to ensure completion.

Click here to start a scholarship application.

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Underrepresented Trainee Scholarships are also available...
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