Keystone Symposia

This meeting took place in 2005

For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.

B Cell Development, Function and Disease (C5)

Organizer(s) Harinder Singh, Mark J. Shlomchik and Riccardo Dalla-Favera
March 28—April 3, 2005
Sheraton Steamboat Resort • Steamboat Springs, Colorado USA
Abstract Deadline: Nov 29, 2004
Late Abstract Deadline:
Scholarship Deadline:
Early Registration Deadline: Jan 28, 2005

Supported by The Director's Fund

Summary of Meeting:
The defining feature of B lymphocyte development is the combinatorial recombination of antigen receptor gene segments which results in the generation of a vast repertoire of clonogenic B cells. Each naïve B cell expresses a unique antigen receptor comprised of an antibody molecule associated with signal transduction components. Signaling through the B cell receptor is required for B cell survival, activation in response to antigen and the induction of tolerance. B cell activation in germinal centers is accompanied by somatic hypermutation and isotype switch recombination of immunoglobulin (Ig) genes. The former process is used to select for higher affinity antibodies in an immune response and the latter to generate antibodies with different effector functions. Aberrant B cell activation can result in autoimmune disease or lymphomagenesis. Considerable progress has been recently achieved in several areas including (i) regulation of early B cell development from a lymphoid progenitor, (ii) mechanisms underlying somatic hypermutation and class switching of Ig genes, (iii) signalling functions of the B cell receptor, (iv) analysis of B cell subsets, (v) establishment and functioning of germinal centers (vi) control of plasma cell differentiation and (vii) mechanisms underlying autoimmunity. The meeting represents the continuation of a longstanding forum that uniquely focuses on both murine and human B cell biology so as to promote the analysis of B cell diseases and the generation of new therapeutic approaches. It brings together leading as well as young investigators.

View Meeting Program


Scholarship / Award Information

Scholarship Deadline: (11:59 PM US Mountain Standard Time)
*All deadlines end at 11:59 PM US Mountain Standard Time
NOTE: Please use the button above to Apply for a Scholarship


Keystone Symposia is offering scholarships of up to 1,200 USD to Students and Postdoctoral fellows. These scholarships are to be used to help defray the expenses associated with conference attendance, including airfare (restrictions may apply based on funding source), ground transportation, lodging costs, and a portion of meeting registration. Receipts will be required to receive reimbursement.

Abstracts submitted for poster presentation will be used as the basis for awarding the scholarships. Scholarship recipients will be selected based on the quality of science of the abstract and the relevance of the abstract to the conference topic. Only one application per abstract is accepted. Only one award per lab will be allocated.


To be eligible for a scholarship, you must be:

A graduate student or postdoctoral fellow currently enrolled in an academic institute at the start of the meeting for which you are applying. Note: a graduate student is defined as a student who is studying for a higher degree at an academic institution. A postdoctoral fellow is defined as an individual with a Ph.D., M.D., or DVM degree who is engaged in a temporary period of mentored research and/or scholarly training for the purpose of acquiring the professional skills needed to pursue their desired career path, and is within 6 years of these degrees.

Review Criteria

Criteria for Abstract Review:

  1. Relevance to the meeting topic
  2. Significance of the scientific question and results
  3. Style
    • Organization (e.g. the abstract has a clear beginning, middle and end)
    • Grammar and spelling
  4. Clarity of scientific presentations
    • Clear question or hypothesis
    • Sufficient background
    • The experimental approach and rationale for the approach are clear
    • The results are clearly presented
    • The interpretation and conclusions are reasonable and logical

Application Process

If you are eligible and wish to be considered for a scholarship, you should complete all of the following by the scholarship deadline for the meeting you wish to attend. It is recommended you begin these steps in advance of the deadline date to ensure completion.

Click here to start a scholarship application.

  See the Scholarship FAQ's

Underrepresented Trainee Scholarships are also available...
Please Click Here for more information about Underrepresented Trainee Scholarship.

  See the Underrepresented Trainee Scholarship FAQ's

If you have any questions, please contact