Keystone Symposia

This meeting took place in 2005

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Chromatin Modification Pathways (C7)

Organizer(s) Tony Kouzarides and Shelley L. Berger
March 31—April 5, 2005
Snowbird Resort • Snowbird, UT USA
Abstract Deadline: Nov 30, 2004
Late Abstract Deadline:
Scholarship Deadline:
Early Registration Deadline: Jan 31, 2005

Sponsored by Novartis Institutes for BioMedical Research and The Director's Fund

Summary of Meeting:
It has become apparent over the last few years that histone modifications mediate important biological functions. There is a plethora of these modifications and new ones are being discovered on a regular basis. These modifications are most commonly being studied in the context of transcriptional regulation, since classically modifications on histones were correlated with transcriptional state. However, it is now clear that any biological process involving DNA may be affected and regulated by histone modifications. As a result there are now indications that biological processes such as repair, replication and recombination are also under the control of histone modifications. Another recent development has been the mechanistic link between histone modifications and distinct processes involving nucleic acids such as DNA methylation and RNA interference. Each of these processes are under scrutiny in their own right, but the recent data suggests that each of these is intimately linked with histone modifications in the formation of heterochromatin structures which regulate transcription. Finally, data is now amassing that histone-modifying enzymes are linked to cancer. Inhibitors of deacetylases are now in phase I and II clinical trials and modifying enzymes are found over expressed, mutated and rearranged in cancer cells. The potential of these enzymes for radional drug discovery is therefore only now beginning to be realized. The aim of this meeting is to focus on basic research involving the normal biological functions relating to histone modifications and to highlight the pathways and enzymes that are deregulated in cancer cells.

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Scholarship / Award Information

Scholarship Deadline: (11:59 PM US Mountain Standard Time)
*All deadlines end at 11:59 PM US Mountain Standard Time
NOTE: Please use the button above to Apply for a Scholarship


Keystone Symposia is offering scholarships of up to 1,200 USD to Students and Postdoctoral fellows. These scholarships are to be used to help defray the expenses associated with conference attendance, including airfare (restrictions may apply based on funding source), ground transportation, lodging costs, and a portion of meeting registration. Receipts will be required to receive reimbursement.

Abstracts submitted for poster presentation will be used as the basis for awarding the scholarships. Scholarship recipients will be selected based on the quality of science of the abstract and the relevance of the abstract to the conference topic. Only one application per abstract is accepted. Only one award per lab will be allocated.


To be eligible for a scholarship, you must be:

A graduate student or postdoctoral fellow currently enrolled in an academic institute at the start of the meeting for which you are applying. Note: a graduate student is defined as a student who is studying for a higher degree at an academic institution. A postdoctoral fellow is defined as an individual with a Ph.D., M.D., or DVM degree who is engaged in a temporary period of mentored research and/or scholarly training for the purpose of acquiring the professional skills needed to pursue their desired career path, and is within 6 years of these degrees.

Review Criteria

Criteria for Abstract Review:

  1. Relevance to the meeting topic
  2. Significance of the scientific question and results
  3. Style
    • Organization (e.g. the abstract has a clear beginning, middle and end)
    • Grammar and spelling
  4. Clarity of scientific presentations
    • Clear question or hypothesis
    • Sufficient background
    • The experimental approach and rationale for the approach are clear
    • The results are clearly presented
    • The interpretation and conclusions are reasonable and logical

Application Process

If you are eligible and wish to be considered for a scholarship, you should complete all of the following by the scholarship deadline for the meeting you wish to attend. It is recommended you begin these steps in advance of the deadline date to ensure completion.

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