Keystone Symposia

This meeting took place in 2007

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Molecular Mechanisms of Fibrosis: From Bench to Bedside (C5)

Organizer(s) Thomas A. Wynn, W. Michael Gallatin and Mark Lupher, Jr.
March 11—15, 2007
Granlibakken Tahoe • Tahoe City, CA USA
Abstract Deadline: Nov 13, 2006
Late Abstract Deadline: Dec 12, 2006
Scholarship Deadline: Nov 13, 2006
Early Registration Deadline: Jan 11, 2007

Sponsored by ICOS Corporation

Summary of Meeting:
Tissue fibrosis or scarring is a leading cause of morbidity and mortality worldwide. Current health statistics suggest that almost 45% of all deaths in the western world are attributed to some type of chronic fibrotic disease. Fibrosis affects nearly all tissues and organ systems. Diseases in which fibrosis is a major cause of morbidity and mortality include the interstitial lung diseases, liver cirrhosis, kidney disease, heart disease, systemic sclerosis, among others. Fibrotic tissue remodeling can also influence cancer metastasis and accelerate chronic graft rejection in transplant recipients. Current treatments for fibrotic disorders target the inflammatory cascade, but they have been largely unsuccessful, primarily because the mechanisms that are involved in fibrogenesis are believed to be distinct from those involved in inflammation. Because mechanistic studies are difficult to carry out in humans, numerous experimental models have been developed over the past few years to dissect the immunological and molecular mechanisms of fibrosis. The first of new therapies based on these models is just beginning to approach clinical testing. The goal of this meeting is to bring together academic researchers, clinicians, and members of the pharmaceutical industry to discuss the most recent advances in the field and to identify common mechanistic themes of tissue fibrogenesis in various tissue systems. By bringing together a diverse group of researchers, the meeting will provide a more integrated perspective from basic disease mechanisms through to the more pragmatic challenges of clinical trial design in chronic progressive disease. Some of the topics that will be discussed include: extracellular matrix remodeling in fibrosis and cancer; the role of bone marrow in epithelial-mesenchymal transitions; experimental models of fibrosis; pulmonary, cardiac, liver, and kidney fibrosis; systemic sclerosis (scleroderma); as well as recent clinical developments with experimental anti-fibrotic drugs. This meeting will feature plenary talks from key investigators in the field and will also include workshops and poster sessions.

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Scholarship / Award Information

Scholarship Deadline: November 13, 2006 (11:59 PM US Mountain Standard Time)
*All deadlines end at 11:59 PM US Mountain Standard Time
NOTE: Please use the button above to Apply for a Scholarship


Keystone Symposia is offering scholarships of up to 1,200 USD to Students and Postdoctoral fellows. These scholarships are to be used to help defray the expenses associated with conference attendance, including airfare (restrictions may apply based on funding source), ground transportation, lodging costs, and a portion of meeting registration. Receipts will be required to receive reimbursement.

Abstracts submitted for poster presentation will be used as the basis for awarding the scholarships. Scholarship recipients will be selected based on the quality of science of the abstract and the relevance of the abstract to the conference topic. Only one application per abstract is accepted. Only one award per lab will be allocated.


To be eligible for a scholarship, you must be:

A graduate student or postdoctoral fellow currently enrolled in an academic institute at the start of the meeting for which you are applying. Note: a graduate student is defined as a student who is studying for a higher degree at an academic institution. A postdoctoral fellow is defined as an individual with a Ph.D., M.D., or DVM degree who is engaged in a temporary period of mentored research and/or scholarly training for the purpose of acquiring the professional skills needed to pursue their desired career path, and is within 6 years of these degrees.

Review Criteria

Criteria for Abstract Review:

  1. Relevance to the meeting topic
  2. Significance of the scientific question and results
  3. Style
    • Organization (e.g. the abstract has a clear beginning, middle and end)
    • Grammar and spelling
  4. Clarity of scientific presentations
    • Clear question or hypothesis
    • Sufficient background
    • The experimental approach and rationale for the approach are clear
    • The results are clearly presented
    • The interpretation and conclusions are reasonable and logical

Application Process

If you are eligible and wish to be considered for a scholarship, you should complete all of the following by the scholarship deadline for the meeting you wish to attend. It is recommended you begin these steps in advance of the deadline date to ensure completion.

Click here to start a scholarship application.

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Underrepresented Trainee Scholarships are also available...
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