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This meeting took place in 2010
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Stem Cell Differentiation and Dedifferentiation (B4)
Organizer(s) Shinya Yamanaka and Fiona M. Watt
February 15—20, 2010
Keystone Resort • Keystone, CO USA
Abstract Deadline: Oct 15, 2009
Late Abstract Deadline: Nov 16, 2009
Scholarship Deadline: Oct 15, 2009
Early Registration Deadline: Dec 15, 2009
Sponsored by Genzyme Corporation, Pfizer Global Research & Development and Sangamo BioSciences, Inc.
Summary of Meeting:
Recent progress in induced pluripotent stem (iPS) cells has shown that stem cells can be generated from differentiated progenies by introducing just a few defined factors. In addition, various stem cells have been isolated from human tissues. Stem cells from patients will provide various tools in understanding disease mechanisms, searching for effective drugs, and evaluating toxicity of drug candidates. Furthermore, human iPS cells and other stem cells may provide various types of cells for regenerative medicine. In this meeting, we will discuss how stem cells, including iPS cells, are isolated, generated and maintained. We will also provide an update on induction of differentiated cells from stem cells. We then will discuss progress in application of pluripotent stem cells and other stem cells in basic research, drug discovery, toxicology, and regenerative medicine.
View Scholarships/Awards
Recent progress in induced pluripotent stem (iPS) cells has shown that stem cells can be generated from differentiated progenies by introducing just a few defined factors. In addition, various stem cells have been isolated from human tissues. Stem cells from patients will provide various tools in understanding disease mechanisms, searching for effective drugs, and evaluating toxicity of drug candidates. Furthermore, human iPS cells and other stem cells may provide various types of cells for regenerative medicine. In this meeting, we will discuss how stem cells, including iPS cells, are isolated, generated and maintained. We will also provide an update on induction of differentiated cells from stem cells. We then will discuss progress in application of pluripotent stem cells and other stem cells in basic research, drug discovery, toxicology, and regenerative medicine.
View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference
MONDAY, FEBRUARY 15
TUESDAY, FEBRUARY 16
WEDNESDAY, FEBRUARY 17
THURSDAY, FEBRUARY 18
FRIDAY, FEBRUARY 19
SATURDAY, FEBRUARY 20
Conference Program Print | View meeting in 24 hr (international) time
MONDAY, FEBRUARY 15
7:30—8:30 PM
Keynote Address
*
Shinya Yamanaka,
Center for iPS Cell Research and Application, Kyoto University, Gladstone Institutes, Japan
James A. Thomson,
Morgridge Institute for Research, University of Wisconsin, USA
Human ES Cells and iPS Cells
Human ES Cells and iPS Cells
8:00—11:15 AM
iPS Cells
Shinya Yamanaka,
Center for iPS Cell Research and Application, Kyoto University, Gladstone Institutes, Japan
Induction of Pluripotency by Defined Factors
Induction of Pluripotency by Defined Factors
Rudolf Jaenisch,
Whitehead Institute for Biomedical Research, USA
Molecular Mechanisms of Pluripotency and Reprogramming
Molecular Mechanisms of Pluripotency and Reprogramming
Juan Carlos Izpisua-Belmonte,
The Salk Institute for Biological Studies, USA
Linking the p53 Tumor Suppressor Pathway to Somatic Cell Reprogramming
Linking the p53 Tumor Suppressor Pathway to Somatic Cell Reprogramming
Helen M. Blau,
Stanford University, USA
Reprogramming Towards Pluripotency Requires AID-Dependent DNA Demethylation
Reprogramming Towards Pluripotency Requires AID-Dependent DNA Demethylation
Jing Liao,
Harvard University, USA
Short Talk: Generation of Induced Pluripotent Stem Cell Lines from Rat Adult Cells
Short Talk: Generation of Induced Pluripotent Stem Cell Lines from Rat Adult Cells
Christoph Bock,
Austrian Academy of Sciences, Austria
Short Talk: The Epigenome of Pluripotent Cells: Variations of a Common Theme
Short Talk: The Epigenome of Pluripotent Cells: Variations of a Common Theme
5:00—7:15 PM
Pluripotency
*
Shinya Yamanaka,
Center for iPS Cell Research and Application, Kyoto University, Gladstone Institutes, Japan
Austin Smith,
University of Cambridge, UK
Intrinsic and Extrinsic Regulation of the Pluripotent Ground State
Intrinsic and Extrinsic Regulation of the Pluripotent Ground State
Ihor R. Lemischka,
Icahn School of Medicine at Mount Sinai, USA
Genome-Wide Analyses of Molecular Mechanisms Underlying Pluripotency
Genome-Wide Analyses of Molecular Mechanisms Underlying Pluripotency
Amanda G. Fisher,
Imperial College London, UK
Stem Cells and Epigenetic Reprogramming
Stem Cells and Epigenetic Reprogramming
Lay Teng Ang,
Genome Institute of Singapore, Singapore
Short Talk: MicroRNA Function in Regulating Pluripotency and Differentiation of Human Embryonic Stem Cells
Short Talk: MicroRNA Function in Regulating Pluripotency and Differentiation of Human Embryonic Stem Cells
Li-Fang Chu,
University of Wisconsin-Madison, USA
Short Talk: Primordial Germ Cells as the Immediate Precursors of Embryonic Stem Cells
Short Talk: Primordial Germ Cells as the Immediate Precursors of Embryonic Stem Cells
8:00—11:30 AM
Reprogramming
Azim Surani,
University of Cambridge, UK
Resetting the Epigenome during Germ Cell Specification and by LIF-STAT3 Signaling
Resetting the Epigenome during Germ Cell Specification and by LIF-STAT3 Signaling
Hans R. Schöler,
Max Planck Institute for Molecular Biomedicine, Germany
Induction of Pluripotency in Adult Somatic and Germline Stem Cells
Induction of Pluripotency in Adult Somatic and Germline Stem Cells
Kevin C. Eggan,
Harvard University, USA
Identification and Characterization of Small Reprogramming Molecules
Identification and Characterization of Small Reprogramming Molecules
Chad A. Cowan,
Beth Israel Deaconess Medical Center, USA
Programming and Reprogramming: New Approaches for Understanding Disease
Programming and Reprogramming: New Approaches for Understanding Disease
Azadeh Golipour,
Samuel Lunenfeld Research Institute, Canada
Short Talk: A Systematic Approach to Identify Novel Regulators of Somatic Cell Reprogramming
Short Talk: A Systematic Approach to Identify Novel Regulators of Somatic Cell Reprogramming
Collin A. Melton,
University of California, San Francisco, USA
Short Talk: Opposing microRNA Families Regulate Self-Renewal in Mouse Embryonic Stem Cells
Short Talk: Opposing microRNA Families Regulate Self-Renewal in Mouse Embryonic Stem Cells
Larry Stanton,
Genome Institute of Singapore, Singapore
Short Talk: Converting Sox17 into a Pluripotency Reprogramming Factor
Short Talk: Converting Sox17 into a Pluripotency Reprogramming Factor
5:00—7:00 PM
Other Pluripotent Stem Cells
Takashi Shinohara,
Kyoto University, Japan
Positive and Negative Regulators of Mouse Germline Stem (GS) Cell Proliferation
Positive and Negative Regulators of Mouse Germline Stem (GS) Cell Proliferation
Thomas P. Zwaka,
Icahn School of Medicine at Mount Sinai, USA
Short Talk
Short Talk
Shin-Ichi Nishikawa,
RIKEN Center for Developmental Biology, Japan
The Pathway of Hematopoietic Stem Cell Development Explained
The Pathway of Hematopoietic Stem Cell Development Explained
8:00—11:15 AM
Somatic Stem Cells
Toshio Suda,
Keio University, Japan
Hematopoietic Stem Cells and their Niches
Hematopoietic Stem Cells and their Niches
Fred H. Gage,
The Salk Institute for Biological Studies, USA
Neural Stem Cells and their Fates
Neural Stem Cells and their Fates
Tae-Hee Kim,
Hospital for Sick Children, University of Toronto, Canada
Short Talk: A Role for Notch Signaling in Stomach Epithelial Stem Cell Homeostasis
Short Talk: A Role for Notch Signaling in Stomach Epithelial Stem Cell Homeostasis
5:00—7:30 PM
Differentiation of Stem Cells I
*
Toshio Suda,
Keio University, Japan
Deepak Srivastava,
Gladstone Institute of Cardiovascular Disease and University of California, San Francisco, USA
microRNA Regulation of Cardiac Stem Cell Fate
microRNA Regulation of Cardiac Stem Cell Fate
Hideyuki Okano,
Keio University School of Medicine, Japan
Regeneration of the Damaged CNS with iPS Cells
Regeneration of the Damaged CNS with iPS Cells
Hans Keirstead,
University of California, Irvine, USA
Clinically-Compliant Differentiation of hESCs for the Treatment of Spinal Cord Injury and Disease
Clinically-Compliant Differentiation of hESCs for the Treatment of Spinal Cord Injury and Disease
Catherin Niemann,
University of Cologne, Germany
Short Talk: Important Role of Hair Follicle Stem Cells for Generation and Differentiation of Sebaceous Gland Cells during Skin Homeostasis
Short Talk: Important Role of Hair Follicle Stem Cells for Generation and Differentiation of Sebaceous Gland Cells during Skin Homeostasis
8:00—11:00 AM
Differentiation of Stem Cells II
*
Deepak Srivastava,
Gladstone Institute of Cardiovascular Disease and University of California, San Francisco, USA
Emmanuel E. Baetge,
Nestlé Institute of Health Sciences, Switzerland
Functional Pancreatic Islet Cells from Embryonic Stem Cells
Functional Pancreatic Islet Cells from Embryonic Stem Cells
Ronald D. McKay,
Lieber Institute for Brain Development, USA
Neural Differentiation of Stem Cells
Neural Differentiation of Stem Cells
Nobuko Uchida,
StemCells, Inc., USA
Therapeutic Potential of Human Central Nervous System-Stem Cell: Neuroprotection Strategies
Therapeutic Potential of Human Central Nervous System-Stem Cell: Neuroprotection Strategies
Micha Drukker,
Helmholtz Center Munich, Germany
Short Talk: Prospective Isolation of Four of the Earliest Precursors to Emerge from Human Embryonic Stem Cells
Short Talk: Prospective Isolation of Four of the Earliest Precursors to Emerge from Human Embryonic Stem Cells
5:00—7:00 PM
Application of Stem Cells
*
Ronald D. McKay,
Lieber Institute for Brain Development, USA
Amy Sinor,
Harvard Stem Cell Institute, USA
ES Cell-Derived Cells for Disease Mechanism and Drug Discovery
ES Cell-Derived Cells for Disease Mechanism and Drug Discovery
Zhong Zhong,
GlaxoSmithKline R&D China, China
Drug Discovery Targeting Neural Stem Cells
Drug Discovery Targeting Neural Stem Cells
Gabriela Gebrin Cezar,
Pfizer, Brazil
Metabolomics of Human Embryonic Stem Cells: Unraveling Biochemical Pathways of Neurodevelopmental Disorders
Metabolomics of Human Embryonic Stem Cells: Unraveling Biochemical Pathways of Neurodevelopmental Disorders
Karl-Dimiter Bissig,
Baylor College of Medicine, USA
Short Talk: Cell Based Therapy for Liver Disease
Short Talk: Cell Based Therapy for Liver Disease
*Session Chair †Invited, not yet responded.
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We gratefully acknowledge the generous grant for this conference provided by:
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