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This meeting took place in 2015
Here are the related meetings in 2021:
Harnessing the Microbiome for Disease Prevention and Therapy - RESCHEDULING IN PROGRESS (J4)
For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.
Gut Microbiota Modulation of Host Physiology: The Search for Mechanism (C1)
Organizer(s) Fredrik Bäckhed, Ruth E. Ley and Yasmine Belkaid
March 1—6, 2015
Keystone Resort • Keystone, CO USA
Discounted Abstract Deadline: Nov 3, 2014
Abstract Deadline: Dec 2, 2014
Scholarship Deadline: Nov 3, 2014
Discounted Registration Deadline: Jan 5, 2015
Sponsored by Boehringer Ingelheim Pharmaceuticals, Inc., Cell Research, Nestlé Institute of Health Sciences, Novartis Institutes for BioMedical Research and Theravance Biopharma
Summary of Meeting:
Over the past decade, it has become evident that the gut microbiome is an important environmental factor that affects many physiologic processes, such as cell proliferation and differentiation, behavior, immune function and metabolism. Moreover, it may contribute to a wide variety of diseases, including cancer, inflammatory diseases, metabolic diseases and responses to pathogens. This meeting will emphasize mechanistic understandings of the relationship between microbiota and host physiology, rather than simply characterize microbiota in different disease states. Speakers will address not only bacteria in the gut, but also fungi and microbiome on the skin and in the lung. The goal of the meeting is to facilitate the understanding by which mechanisms of the microbiota modulate host physiologic processes and increase our understanding of how an altered microbiota contributes to health and disease in humans. In addition, the broad representation of speakers from diverse fields, such as microbiology, immunology, physiology and infectious disease, is likely to foster new collaborations.
View Scholarships/Awards
Over the past decade, it has become evident that the gut microbiome is an important environmental factor that affects many physiologic processes, such as cell proliferation and differentiation, behavior, immune function and metabolism. Moreover, it may contribute to a wide variety of diseases, including cancer, inflammatory diseases, metabolic diseases and responses to pathogens. This meeting will emphasize mechanistic understandings of the relationship between microbiota and host physiology, rather than simply characterize microbiota in different disease states. Speakers will address not only bacteria in the gut, but also fungi and microbiome on the skin and in the lung. The goal of the meeting is to facilitate the understanding by which mechanisms of the microbiota modulate host physiologic processes and increase our understanding of how an altered microbiota contributes to health and disease in humans. In addition, the broad representation of speakers from diverse fields, such as microbiology, immunology, physiology and infectious disease, is likely to foster new collaborations.
View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference
SUNDAY, MARCH 1
MONDAY, MARCH 2
TUESDAY, MARCH 3
WEDNESDAY, MARCH 4
THURSDAY, MARCH 5
FRIDAY, MARCH 6
Conference Program Print | View meeting in 24 hr (international) time
SUNDAY, MARCH 1
6:00—8:00 PM
Welcome Mixer
No registration fees are used to fund alcohol served at this function.
8:00—8:15 AM
Welcome Remarks
Fredrik Bäckhed,
University of Gothenburg, Sweden
Ruth E. Ley,
Max Planck Institute for Developmental Biology, Germany
Yasmine Belkaid,
NIAID, National Institutes of Health, USA
8:15—9:15 AM
Keynote Address
*
Fredrik Bäckhed,
University of Gothenburg, Sweden
Herbert (Skip) W. Virgin,
Vir Biotechnology, USA
Role of the Virome and Virome-Bacterial Microbiome Interactions in Immunity and Disease
Role of the Virome and Virome-Bacterial Microbiome Interactions in Immunity and Disease
9:15—11:00 AM
Gut Microbiota and Metabolic Disease
*
Patrice D. Cani,
Université Catholique de Louvain, Belgium
Naoko Ohtani,
Osaka City University Graduate School of Medicine, Japan
Obesity-Induced Gut Microbial Metabolite, DCA, Promotes Liver Cancer through Senescence Secretome
Obesity-Induced Gut Microbial Metabolite, DCA, Promotes Liver Cancer through Senescence Secretome
Megan T. Baldridge,
Washington University School of Medicine, USA
Short Talk: Heritable Fecal IgA Levels Distinguish Extra-Chromosomal Phenotypic Variation
Short Talk: Heritable Fecal IgA Levels Distinguish Extra-Chromosomal Phenotypic Variation
2:30—4:30 PM
Workshop 1: Novel Models to Study Host-Microbe Interactions
*
François Leulier,
Institut de Génomique Fonctionnelle de Lyon, France
Juris A. Grasis,
San Diego State University, USA
The Basal Metazoan Hydra as a Model for Host-Mucosa-Virome Interactions
The Basal Metazoan Hydra as a Model for Host-Mucosa-Virome Interactions
Jennifer S. Hampton,
University of Oregon, USA
Microbial Signaling Mechanisms Important for Pancreatic Beta Cell Expansion in Zebrafish
Microbial Signaling Mechanisms Important for Pancreatic Beta Cell Expansion in Zebrafish
Siegfried Hapfelmeier,
University of Bern, Switzerland
Next-Generation Models of Reversible Intestinal Colonization: Probing Mucosal Immunity
Next-Generation Models of Reversible Intestinal Colonization: Probing Mucosal Immunity
Carolyn Elya,
University of California, Berkeley, USA
Employing Drosophila Melanogaster to Investigate How Gut Microbes affect Host Behavior
Employing Drosophila Melanogaster to Investigate How Gut Microbes affect Host Behavior
Kate P. Coyle,
North Carolina State University, USA
Impact of Dietary Adaptation on Gastrointestinal Biology across Trophic Levels in Lake Malawi Cichlids
Impact of Dietary Adaptation on Gastrointestinal Biology across Trophic Levels in Lake Malawi Cichlids
Claire Maynard,
Durham University, UK
A Novel Mechanism to Improve Host Health by Intervening with Microbial Metabolism Discovered Using the C. elegans: E. coli Model
A Novel Mechanism to Improve Host Health by Intervening with Microbial Metabolism Discovered Using the C. elegans: E. coli Model
Meng Wu,
Washington University in St. Louis, USA
Identifying the Genetic Underpinnings of Niche in Human Gut Bacteria in Different Diet Contexts Using Multi-Taxon INSeq and Gnotobiotic Mice
Identifying the Genetic Underpinnings of Niche in Human Gut Bacteria in Different Diet Contexts Using Multi-Taxon INSeq and Gnotobiotic Mice
5:00—7:15 PM
Microbiota-Diet Interactions
Stanley L. Hazen,
Cleveland Clinical Foundation, USA
Diet, Microbiota and Cardiometabolic Disease
Diet, Microbiota and Cardiometabolic Disease
Patrice D. Cani,
Université Catholique de Louvain, Belgium
Gut Microbes, Host and Diet: Focus on a Novel Lipid Sensor
Gut Microbes, Host and Diet: Focus on a Novel Lipid Sensor
Amir Zarrinpar,
University of California, San Diego and The Salk Institute, USA
Short Talk: Diet and Feeding Pattern Affect the Diurnal Dynamics of the Gut Microbiome
Short Talk: Diet and Feeding Pattern Affect the Diurnal Dynamics of the Gut Microbiome
*
Liping Zhao,
Shanghai Jiao Tong University, China and Rutgers University, USA
Dysbiosis of Gut Microbiota as a Checkpoint for Obesity Development
Dysbiosis of Gut Microbiota as a Checkpoint for Obesity Development
Shirong Liu,
Brigham and Women's Hospital/Harvard Medical School, USA
Short Talk: Identification of Fecal MicroRNAs and their Role in Regulating Gut Microbiota
Short Talk: Identification of Fecal MicroRNAs and their Role in Regulating Gut Microbiota
7:15—8:15 PM
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.
8:00—11:15 AM
Microbiota Induction of the Immune System I
*
Fiona M. Powrie,
University of Oxford, UK
Yasmine Belkaid,
NIAID, National Institutes of Health, USA
Compartmentalized Control of Tissue Immunity by Commensals
Compartmentalized Control of Tissue Immunity by Commensals
Dan R. Littman,
HHMI/New York University School of Medicine, USA
Programming of T Cell Effector Functions by the Intestinal Microbiota
Programming of T Cell Effector Functions by the Intestinal Microbiota
Wendy S. Garrett,
Harvard School of Public Health, USA
Short-Chain Fatty Acids and Regulatory T Cells
Short-Chain Fatty Acids and Regulatory T Cells
Thaddeus S. Stappenbeck,
Cleveland Clinic, USA
Short Talk: Regulation of Epithelial Turnover and Repair by Host-Virome Interactions
Short Talk: Regulation of Epithelial Turnover and Repair by Host-Virome Interactions
Thomas C. Fung,
University of Pennsylvania, USA
Short Talk: A Lymphoid Tissue-Resident Commensal Bacterium Modulates Local Immune Responses in the Intestine
Short Talk: A Lymphoid Tissue-Resident Commensal Bacterium Modulates Local Immune Responses in the Intestine
5:00—7:00 PM
Microbiota Induction of the Immune System II
*
Wendy S. Garrett,
Harvard School of Public Health, USA
Fiona M. Powrie,
University of Oxford, UK
Mucosal Inflammation: From IBD to Colon Cancer
Mucosal Inflammation: From IBD to Colon Cancer
Andrew J.S. Macpherson,
University of Bern, Switzerland
Stratification of Intestinal Microbes
Stratification of Intestinal Microbes
Duane R. Wesemann,
Harvard Medical School, USA
Short Talk: Role of Microbes in B Cell Lymphopoiesis and Early Ig Repertoire Development
Short Talk: Role of Microbes in B Cell Lymphopoiesis and Early Ig Repertoire Development
7:00—8:00 PM
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.
8:00—11:15 AM
Emerging Areas of Host-Microbiome Interactions
*
John F. Rawls,
Duke University, USA
David M. Underhill,
Cedars-Sinai Medical Center, USA
Intestinal Fungi and their Role in Disease
Intestinal Fungi and their Role in Disease
Julie A. Segre,
National Institutes of Health, USA
Skin Microbiome: Bacterial, Fungal Diversity Across the Human Landscape
Skin Microbiome: Bacterial, Fungal Diversity Across the Human Landscape
François Leulier,
Institut de Génomique Fonctionnelle de Lyon, France
Host/Lactobacilli Mutualism: "Learning on the Fly"
Host/Lactobacilli Mutualism: "Learning on the Fly"
Marie-Claire Arrieta,
University of Calgary, Canada
Short Talk: Early-Infancy Microbial and Metabolic Alterations Impact Risk of Asthma
Short Talk: Early-Infancy Microbial and Metabolic Alterations Impact Risk of Asthma
Anisa S. Ismail,
Princeton University, USA
Short Talk: Identification of a Host-Produced Molecule that Mimics Autoinducer-2 (AI-2) Activity
Short Talk: Identification of a Host-Produced Molecule that Mimics Autoinducer-2 (AI-2) Activity
Elisabeth Kernbauer,
New York University School of Medicine, USA
Short Talk: An Enteric Viral Infection Can Functionally Replace the Beneficial Cues Provided by Commensal Bacteria
Short Talk: An Enteric Viral Infection Can Functionally Replace the Beneficial Cues Provided by Commensal Bacteria
Jean-Marc Chatel,
Micalis Institute, France
Short Talk: Identification of an Anti-Inflammatory Protein from Faecalibacterium prausnitzii, a Commensal Bacterium Deficient in Crohn's Disease
Short Talk: Identification of an Anti-Inflammatory Protein from Faecalibacterium prausnitzii, a Commensal Bacterium Deficient in Crohn's Disease
5:00—7:00 PM
Mucus-Microbiota Interactions
*
Justin L. Sonnenburg,
Stanford University, USA
Lora V. Hooper,
University of Texas Southwestern Medical Center, USA
Circadian Regulation of Intestinal Host-Microbe Interactions
Circadian Regulation of Intestinal Host-Microbe Interactions
Eric C. Martens,
University of Michigan Medical School, USA
Think Globally, Act Locally: Regulated Deployment of Diet and Mucus Polysaccharide Degradation by Gut Bacteria
Think Globally, Act Locally: Regulated Deployment of Diet and Mucus Polysaccharide Degradation by Gut Bacteria
Hiutung Chu,
California Institute of Technology, USA
Short Talk: Microbiota-Induced Autophagy Promotes Mucosal Tolerance
Short Talk: Microbiota-Induced Autophagy Promotes Mucosal Tolerance
7:00—8:00 PM
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.
8:00—11:00 AM
Gut Microbiota in Relation to Infectious Diseases
*
Lora V. Hooper,
University of Texas Southwestern Medical Center, USA
Wolf-Dietrich Hardt,
ETH Zürich, Switzerland
Salmonella Diarrhea Results from Multiple Pathogen-Microbiota-Host Interactions
Salmonella Diarrhea Results from Multiple Pathogen-Microbiota-Host Interactions
Justin L. Sonnenburg,
Stanford University, USA
Interactions between the Microbiota and Pathogenic Bacteria
Interactions between the Microbiota and Pathogenic Bacteria
Gabriel Nuñez,
University of Michigan, USA
Control of Enteric Pathogens by Host Immunity and the Microbiota
Control of Enteric Pathogens by Host Immunity and the Microbiota
Eric G. Pamer,
University of Chicago, USA
Microbiota-Mediated Defense Against Intestinal Infection
Microbiota-Mediated Defense Against Intestinal Infection
Mario M. Zaiss,
École Polytechnique Fédérale de Lausanne, EPFL, Switzerland
Short Talk: Intestinal Helminths Modulate Allergic Inflammation Indirectly by Altering Bacterial Metabolism
Short Talk: Intestinal Helminths Modulate Allergic Inflammation Indirectly by Altering Bacterial Metabolism
2:30—4:30 PM
Panel: The Integrative Human Microbiome Project (iHMP): Dynamic Analysis of Microbiome-Host Omics Profiles during Periods of Human Health and Disease
The Integrative Human Microbiome Project (iHMP) is the second phase of the National Institute of Health (NIH) Common Fund's Human Microbiome Project (HMP) program. The mission of the overall HMP is to generate resources to permit comprehensive characterization of the human microbiota to further our understanding of how the microbiome impacts human health and disease. In this phase of the program, the iHMP is creating integrated longitudinal datasets of biological properties from both the microbiome and host from three different cohort studies of microbiome-associated conditions using multiple "omics" technologies. Tools, datasets and other resources from the first phase of the project are available at the HMP DACC. During this session, we will provide an overview of the data and resources freely available to the research community as derived from the three iHMP projects: 1) the Multi-Omic Microbiome Study: Pregnancy Initiative (MOMS-PI) at Virginia Commonwealth University, 2) the Inflammatory Bowel Disease Multi'omic Data (IBDMDB) resource from the Broad Institute and a nation-wide research tam, and 3) Integrated Personal 'Omics Profiling (IPOP) from Stanford University and the Jackson Laboratory for Genomic Medicine. For more information or to get involved with the iHMP, please see http://hmp2.org.
Robert W. Karp,
National Institutes of Health, USA
Gregory A. Buck,
Virginia Commonwealth University, USA
Curtis Huttenhower,
Harvard School of Public Health, USA
Wenyu Zhou,
Stanford University, USA
5:00—6:45 PM
Microbiome Interactions with Host Genetics: Future Insights to New Mechanisms
*
Gabriel Nuñez,
University of Michigan, USA
Jens Walter,
University of Alberta, Canada
Bacterial Genetic Factors that Determine Host-Specific Colonization: The Case of Lactobacilli
Bacterial Genetic Factors that Determine Host-Specific Colonization: The Case of Lactobacilli
John F. Rawls,
Duke University, USA
Microbial Regulation of Intestinal Lipid Metabolism and Gene Expression
Microbial Regulation of Intestinal Lipid Metabolism and Gene Expression
Ruth E. Ley,
Max Planck Institute for Developmental Biology, Germany
Host Genetics Analyses of Microbiome Composition: Gene Screens for Identifying Novel Mechanisms
Host Genetics Analyses of Microbiome Composition: Gene Screens for Identifying Novel Mechanisms
6:45—7:15 PM
Meeting Wrap-Up
Organizers will discuss outcomes, future directions and present their choice of poster award.
7:15—8:15 PM
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.
8:00—11:00 PM
Entertainment
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.
*Session Chair †Invited, not yet responded.
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