Keystone Symposia

Firenze Fiera - Fortezza da Basso Floorplan

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This meeting took place in 2020



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MEETING CANCELLED: Transforming Vaccinology (L2)


Organizer(s) Rino Rappuoli, Lynda M. Stuart and Federica Sallusto
March 15—19, 2020
Firenze Fiera - Fortezza da Basso • Florence, Italy
Discounted Abstract Deadline: Nov 12, 2019
Abstract Deadline: Dec 10, 2019
Scholarship Deadline: Nov 12, 2019
Discounted Registration Deadline: Jan 14, 2020

Organized in collaboration with Menarini International Foundation

Part of the Keystone Symposia Global Health Series, supported by the Bill & Melinda Gates Foundation

Sponsored by GlaxoSmithKline Biologicals and Moderna

Summary of Meeting:
Along with clean water and antibiotics, vaccination has allowed mankind to conquer the infectious diseases that used to eradicate about 50% of children. Over the last century, vaccination has also extended life expectancy from under 50 to over 80 years of age. Now that the most important vaccines for infants and children are available, vaccination faces new challenges with the intent to bring the benefits of vaccines to other age groups, emerging infections, antimicrobial resistance, diseases that afflict low-income countries, and to improve therapies against chronic infectious diseases, cancer, autoimmune and neurodegenerative diseases. This new vaccine ambition is supported by the incredible advances in science and technology that make it technically possible to develop vaccines against many new targets and by innovative approaches to vaccine development for emerging infections and for diseases of low-income countries. The technologies that are transforming vaccinology are structure-based design, adjuvants, nucleic acid vaccines (especially RNA), viral vectors, systems biology, and controlled human infections. They are supported by scientific advances in human immunology, genomics, synthetic biology, molecular structure of antigens and antigen-antibody complexes, germinal centers, and microbiome. Conference participants will be exposed to the multidisciplinary technologies that are transforming vaccinology, including the efforts of CEPI, Bill and Melinda Gates Foundation and Wellcome Trust, to change the way vaccines are developed.

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