Keystone Symposia

Granlibakken Tahoe Floorplan

This meeting took place in 2022


Here are the related meetings in 2024:
Mammalian Somatosensation: Mechanisms of Itch, Touch, Pain and Interoreception in Health and Disease (Q2)

For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.

Vertebrate Sensory Systems - RESCHEDULED (RB2)


Organizer(s) Ardem Patapoutian, Ulrich Mueller and Lisa Stowers
October 23—26, 2022
Granlibakken Tahoe • Tahoe City, CA USA
Abstract Deadline: Jul 12, 2022
Scholarship Deadline: Oct 27, 2021
Discounted Registration Deadline: Aug 23, 2022

Supported by the Directors' Fund

Summary of Meeting:
While external sensory systems-- touch, taste, vision, hearing, and smell-- enable us to perceive the world around us, internal sensory systems enable us to perceive the hidden world within us. Recent advances have revealed the molecular mechanisms of how some sensory systems work, but other sensory systems remain uncharted. Fields of sensory biology often maintain separate cultures, independently studying different factors and exploring different frontiers through divergent perspectives, resulting in disjointed research at varying states of scientific maturity. The goal of this meeting is to bring leading experts from different sensory fields together, and to cross-pollinate conceptual and technical advances between these discordant fields. The meeting will highlight recent advances in each external sense (vision, olfaction, taste, hearing, and touch/pain/temperature sensation) as well as new developments in the emerging field of internal organ sensation. Speakers will discuss a range of topics including (1) receptors and sensory mechanisms, (2) neural circuits, (3) behavioral and physiological responses, and (4) the genetic basis of sensory deficits. The mechanistic and ideological insights from each sensory field will provide novel research tools and directions to enable advances in many others. Bringing these communities together, to share their knowledge and strengths, will create a synergistic environment that will vastly accelerate progress in all of these fields, and initiate a collaborative culture which will build on itself long after the conclusion of the meeting.

View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


The meeting will begin on Sunday, October 23 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Wednesday, October 26 with a closing plenary session from 17:00 to 19:00, followed by dinner. We recommend return travel on Thursday, October 27 in order to fully experience the meeting.

SUNDAY, OCTOBER 23

16:00—20:00
Arrival and Registration

Pre Function
18:00—20:00
Welcome Mixer
No registration fees are used to fund alcohol served at this function.

Cedar House

MONDAY, OCTOBER 24

07:00—08:00
Breakfast

Granhall
08:00—09:00
Welcome and Keynote Address (8:00 am Start)

Mountain/Lake
* Ardem Patapoutian, The Scripps Research Institute, USA

David Julius, University of California, San Francisco, USA
Natural Products as Probes of the Pain Pathway: From Physiology to Atomic Structure

09:00—11:00
Sensory Signals Driving Social Interactions (9:00 am Start)

Mountain/Lake
* Jeffrey R. Holt, Boston Children's Hospital, USA

Cory Miller, University of California, San Diego, USA
Social Communication and the Marmoset Brain

Coffee Break

Lisa Stowers, The Scripps Research Institute, USA
How Olfaction Drives Behavior

Susana Lima, Champalimaud Research, Portugal
Central Circuits that Promote Sexual Behavior

11:00—11:30
NIH Brain Initiative Outreach (11:00 am Start)

Mountain/Lake
James Gnadt, NINDS, National Institutes of Health, USA

Karen K. David, NINDS, National Institutes of Health, USA

11:30—17:00
On Own for Lunch

11:30—13:00
Poster Setup

Pavilion
13:00—22:00
Poster Viewing

Pavilion
15:00—16:30
Workshop 1 (3pm Start)

Mountain/Lake
* Lisa Stowers, The Scripps Research Institute, USA

Farin B. Bourojeni, McGill University / IRCM, Canada
Genetic Identification of a Spinothalamic Pathway for Somatosensory Integration during Locomotion

Predrag Jovanovic, Cedars-Sinai Medical Center, USA
Acute Activation of Olfactory Neurons Results in Sex-specific Modulation of Energy Homeostasis

Kara Marshall, Baylor College of Medicine, USA
Lighting Up Mechanosensation

Slav Bagriantsev, Yale University, USA
Lamellar Cells in Mechanosensory Corpuscles are Touch Sensors

Yujuan Su, University of California, San Diego, USA
Brainstem Dbh+ Neurons Control Chronic Allergen-Induced Airway Hyperreactivity

16:30—17:00
Coffee Available

Pre Function
17:00—19:00
Sensational Sensation (5:00 pm Start)

Mountain/Lake
* Fabio Papes, University of Campinas, Brazil

Cynthia F. Moss, Johns Hopkins University, USA
3D Auditory Scene Analysis is Modulated by Spatial Attention

Gary R. Lewin, Max Delbrück Center for Molecular Medicine, Germany
Touch Tethers

Sophie Scott, University College London, UK
Human Sensory Processing of Vocalization

Matt Smear, University of Oregon, USA
Short Talk: Neural Correlates of State and Place in the Olfactory Bulb of Freely-moving Mice

19:00—20:00
Dinner and Social Hour
No registration fees are used to fund alcohol served at this function.

Granhall
19:30—22:00
Poster Session 1

Pavilion

TUESDAY, OCTOBER 25

07:00—08:00
Breakfast

Granhall
08:00—11:00
Sensing Force: Molecules to Circuits (8:00 am Start)

Mountain/Lake
* Swetha Murthy, Oregon Health and Science University, USA

Ulrich Mueller, Johns Hopkins University/The Solomon H. Snyder, USA
Mechanotransduction in Hearing and Auditory Circuit Development

Ardem Patapoutian, The Scripps Research Institute, USA
Mechanical Sensing in Somatosensation and Interoception

Coffee Break

David D. Ginty, HHMI/Harvard Medical School, USA
Mechanosensory Neurons and Central Circuits of Touch

Rachel Clary, University of California - Berkeley, USA
Short Talk: The Spatiotemporal Dynamics of Sensory Neuron and Merkel-cell Remodeling are Decoupled During Epidermal Homeostasis

Charles Dhong, University of Delaware, USA
Short Talk: Materials Chemistry Approaches to Controlling Tactile Cues Reveals Fundamental Percepts

Xiangyu Ren, The Salk Institute, USA
Short Talk: A Novel Spinoparabrachial Pathway for Mechanical Itch

Wang Zheng, Boston Children's Hospital, USA
Short Talk: Oligomerization State Dictates Mechanically-activated Ion Channel Activity

11:00—17:00
On Own for Lunch

11:00—13:00
Poster Setup

Pavilion
13:00—22:00
Poster Viewing

Pavilion
15:00—16:30
Career Roundtable (3:00 pm Start)

Alumni
Viviana Gradinaru, California Institute of Technology, USA

Sebastian Poliak, Kallyope, USA

James Gnadt, NINDS, National Institutes of Health, USA

Karen K. David, NINDS, National Institutes of Health, USA

Esther Florsheim, Arizona State University, USA

16:30—17:00
Coffee Available

Pre Function
17:00—19:00
Making Sense of Sense (5:00 pm Start)

Mountain/Lake
* Ron Congrong Yu, Stowers Institute for Medical Research, USA

Viviana Gradinaru, California Institute of Technology, USA
Functional Transgene Expression throughout the Nervous Systems in Rodent, Marmoset, and Macaque via Intravenous Engineered AAVs

Sandeep Robert Datta, Harvard Medical School, USA
A Transcriptional Rheostat Couples Past Activity to Future Sensory Responses

Jennifer M. Li, Max Planck Institute for Biological Cybernetics, Germany
The Ancestral Origin of Cognitive Maps in the Vertebrate Brain

Elizabeth L. Hanson Moss, Baylor College of Medicine, USA
Short Talk: A Distributed Odor Code in the Olfactory Bulb of Awake, Behaving mice

Michelle M. Dourado, Genentech, USA
Short Talk: Distinct Transcriptional Programs are Revealed in Cross-species Single-nucleus atlas of Dorsal Root Ganglia(DRG) Sensory Neurons

19:00—20:00
Dinner and Social Hour
No registration fees are used to fund alcohol served at this function.

Granhall
19:30—22:00
Poster Session 2

Pavilion

WEDNESDAY, OCTOBER 26

07:00—08:00
Breakfast

Granhall
08:00—11:00
Pain, Anesthesia, and the Internal State (8:00 am Start)

Mountain/Lake
* Theanne N. Griffith, UC Davis, USA

Gregory Scherrer, University of North Carolina at Chapel Hill, USA
The Neural Basis of Pain Unpleasantness and Its Modulation

Asya Rolls, Technion-Israel Institute of Technology, Israel
Immune Interoception: Brain Representation of Immune Activity

Coffee Break

Alexander Chesler, NCCIH, National Institutes of Health, USA
Decoding Cellular and Molecular Mechanisms for Somatosensory Discrimination

Sebastian Poliak, Kallyope, USA
Towards Therapeutic Targeting of the Gut-Brain Axis

Matthew R. Banghart, UC San Diego, USA
Short Talk: Descending Neural Pathways Drive Placebo Analgesia

Rahul P. Patel, UNC-Chapel Hill, USA
Short Talk: Automated Evaluation of Spontaneous Pain

11:00—17:00
On Own for Lunch

11:00—13:00
Poster Setup

Pavilion
13:00—22:00
Poster Viewing

Pavilion
14:30—16:30
Workshop 2 (2:30 pm Start)

Mountain/Lake
* Ulrich Mueller, Johns Hopkins University/The Solomon H. Snyder, USA

Li Ye, The Scripps Research Institute, USA
Clearing Mammalian Bodies to Visualize the Intact Sensory Systems

Josef Turecek, Harvard Medical School, USA
A Convergent Spinal Cord-brainstem Circuit for Shaping the Central Representation of Touch

Jacob P. Brandt, University of Notre Dame, USA
Piezo1-Mediated Spontaneous Activity of Satellite Glia Impacts DRG Development

Nicole Tsai, UCSF, USA
Trans-Seq: Translating Transcriptomics to Connectomics at Retinotectal Synapses

Satoru Miura, University of California, San Francisco, USA
Differential Processing of Self-generated and External Motion by Mouse Visual Cortex

Chen Ran, Harvard Medical School, USA
The Coding of Internal Senses in the Brainstem

Sampurna Chakrabarti, Max Delbrueck Center for Molecular Medicine, Germany
Elkin1 is a Novel Mechanosensory Protein for Detecting Light Touch

Esther Florsheim, Arizona State University, USA
The Immune Sensing of Food Allergens Promotes Avoidance Behavior

16:30—17:00
Coffee Available

Pre Function
17:00—18:45
Homeostatic Sensation Controls Behavior (5:00 pm Start)

Mountain/Lake
* Lindsey Jane Macpherson, UTSA, USA

Stephen Liberles, Harvard Medical School, USA
Internal Sensory Systems

Scott M. Sternson, HHMI/University of California, San Diego, USA
Behavioral State Coding in the Hypothalamus

Martyn Goulding, The Salk Institute for Biological Studies, USA
Somatosensory Feedback and the Control of Movement

Zhikai Liu, Harvard Medical School, USA
Short Talk: The Organization of the Gravity-sensing system in Zebrafish

18:45—19:00
Meeting Wrap-Up: Outcomes and Future Directions (Organizers) (6:45 pm Start)

Mountain/Lake
19:00—20:00
Dinner and Social Hour
No registration fees are used to fund alcohol served at this function.

Granhall
19:30—22:00
Poster Session 3

Pavilion

THURSDAY, OCTOBER 27

 
Departure


*Session Chair †Invited, not yet responded.



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