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This meeting took place in 2016
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Mitochondrial Dynamics (D2)
Organizer(s) Richard J. Youle and Gia K. Voeltz
April 3—7, 2016
Sheraton Steamboat Resort • Steamboat Springs, CO USA
Discounted Abstract Deadline: Dec 2, 2015
Abstract Deadline: Jan 6, 2016
Scholarship Deadline: Dec 2, 2015
Discounted Registration Deadline: Feb 3, 2016
Sponsored by Merck & Co., Inc.
Summary of Meeting:
Although the realm of mitochondrial dynamics continues to expand as discoveries mount regarding its importance in physiology and medicine, we still do not understand why it is crucial to maintain eukaryotic cell integrity, and we are only beginning to understand the molecular mechanisms and regulation involved. This topic is attracting more and more interest and an increasing number of investigators as the critical role of mitochondrial dynamics has been found very recently to impact innate immunity, cell division and chemoresistance. This Keystone Symposia meeting will thus highlight the latest advances in diverse disciplines including neurology, aging, cancer research, autophagy, membrane morphogenesis, structural biology and bioenergetics. The program groups the best senior and junior scientists in these disciplines to break down barriers between different fields of research and promote innovation. As the most important discoveries in mitochondrial dynamics lie ahead, the interactions at this meeting should play a key role in their advance.
View Scholarships/Awards
Although the realm of mitochondrial dynamics continues to expand as discoveries mount regarding its importance in physiology and medicine, we still do not understand why it is crucial to maintain eukaryotic cell integrity, and we are only beginning to understand the molecular mechanisms and regulation involved. This topic is attracting more and more interest and an increasing number of investigators as the critical role of mitochondrial dynamics has been found very recently to impact innate immunity, cell division and chemoresistance. This Keystone Symposia meeting will thus highlight the latest advances in diverse disciplines including neurology, aging, cancer research, autophagy, membrane morphogenesis, structural biology and bioenergetics. The program groups the best senior and junior scientists in these disciplines to break down barriers between different fields of research and promote innovation. As the most important discoveries in mitochondrial dynamics lie ahead, the interactions at this meeting should play a key role in their advance.
View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference
The meeting will begin on Sunday, April 3 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, April 7 with a closing plenary session from 17:00 to 19:15, followed by a social hour and entertainment. We recommend return travel on Friday, April 8 in order to fully experience the meeting.
SUNDAY, APRIL 3
MONDAY, APRIL 4
TUESDAY, APRIL 5
WEDNESDAY, APRIL 6
THURSDAY, APRIL 7
FRIDAY, APRIL 8
Conference Program Print | View meeting in 12 hr (am/pm) time
The meeting will begin on Sunday, April 3 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, April 7 with a closing plenary session from 17:00 to 19:15, followed by a social hour and entertainment. We recommend return travel on Friday, April 8 in order to fully experience the meeting.
SUNDAY, APRIL 3
08:00—09:00
Welcome and Keynote Address
*
Richard J. Youle,
NINDS, National Institutes of Health, USA
Bruce M. Spiegelman,
Harvard Medical School, USA
White, Brown and Beige Fat: Basic Biology and a Novel Effector of Uncoupled Respiration
White, Brown and Beige Fat: Basic Biology and a Novel Effector of Uncoupled Respiration
09:00—11:45
Architecture of the Inner Mitochondrial Membrane
*
Thomas Langer,
CECAD Research Center, Germany
Mitochondrial Membrane Scaffolds and Phospholipid Trafficking
Mitochondrial Membrane Scaffolds and Phospholipid Trafficking
Nikolaus Pfanner,
University of Freiburg, Germany
Mitochondrial Machineries for Protein Import and Assembly
Mitochondrial Machineries for Protein Import and Assembly
Agnieszka Chacinska,
University of Warsaw, Poland
Cellular Responses to Defects in Mitochondrial Protein Biogenesis
Cellular Responses to Defects in Mitochondrial Protein Biogenesis
Luca Scorrano,
University of Padova, Italy
Systemic Adaptation to Changes in Cristae Shape and Mitochondrial Dynamics
Systemic Adaptation to Changes in Cristae Shape and Mitochondrial Dynamics
17:00—19:30
Mitochondrial Fission and Fusion
Adam Frost,
University of California, San Francisco, USA
Cryo-EM Structure of a Mitochondrial Dynamin-Adaptor Complex
Cryo-EM Structure of a Mitochondrial Dynamin-Adaptor Complex
Mike Ryan,
Monash University, Australia
Characterization of Mammalian Adaptors in Mitochondrial Division
Characterization of Mammalian Adaptors in Mitochondrial Division
*
Jodi Nunnari,
University of California, Davis, USA
The Function of the MICOS Complex
The Function of the MICOS Complex
Mickael Cohen,
CNRS-UPMC, France
Short Talk: Tethering Ring Structures Trigger Mitochondrial Fusion
Short Talk: Tethering Ring Structures Trigger Mitochondrial Fusion
Henry N. Higgs,
Geisel School of Medicine at Dartmouth, USA
Short Talk: Actin Filaments Target the Oligomeric Maturation of Drp1 to Mitochondrial Fission Sites
Short Talk: Actin Filaments Target the Oligomeric Maturation of Drp1 to Mitochondrial Fission Sites
Andrew S. Moore,
Howard Hughes Medical Institute, USA
Short Talk: Dynamic Actin Cycling through Mitochondrial Subpopulations Regulates Mitochondrial Network Morphology
Short Talk: Dynamic Actin Cycling through Mitochondrial Subpopulations Regulates Mitochondrial Network Morphology
19:30—20:30
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.
08:00—11:00
Mitochondrial-Organelle Contact Sites
William A. Prinz,
NIDDK, National Institutes of Health, USA
Lipid Transport to Mitochondria at Membrane Contact Sites
Lipid Transport to Mitochondria at Membrane Contact Sites
György Hajnóczky,
Thomas Jefferson University, USA
Trafficking of Calcium and ROS between Mitochondria and ER
Trafficking of Calcium and ROS between Mitochondria and ER
*
Gia K. Voeltz,
University of Colorado Boulder, USA
Multiple Dynamin Family Members Collaborate to Drive Mitochondrial Division
Multiple Dynamin Family Members Collaborate to Drive Mitochondrial Division
Maya B. Schuldiner,
Weizmann Institute of Science, Israel
Mapping Mitochondrial Contact Sites with Diverse Cellular Organelles
Mapping Mitochondrial Contact Sites with Diverse Cellular Organelles
Alyssa Litwiller,
University of Utah, USA
Short Talk: Identification of Machinery Required for Formation of Mitochondrial-Derived Compartments
Short Talk: Identification of Machinery Required for Formation of Mitochondrial-Derived Compartments
11:00—12:00
Career Mentoring: Navigating Your Academic or Biotech Career
L. Stirling Churchman,
Harvard Medical School, USA
Adam L. Hughes,
University of Utah, USA
Ana J. García-Sáez,
University of Tübingen, Germany
Bruce M. Spiegelman,
Harvard Medical School, USA
17:00—19:00
Mitochondrial Motility
Thomas L. Schwarz,
Children's Hospital Boston and Harvard Medical School, USA
Mitochondria, Motors and Mitosis
Mitochondria, Motors and Mitosis
*
Benedikt Westermann,
Universität Bayreuth, Germany
Mitochondrial Motility and Inheritance in Yeast
Mitochondrial Motility and Inheritance in Yeast
Robert S. Balaban,
NHLBI, National Institutes of Health, USA
The Mitochondria Reticulum of Muscle Cells
The Mitochondria Reticulum of Muscle Cells
Brian Cunniff,
Harvard Medical School, USA
Short Talk: Miro1-Mediated Mitochondrial Distribution Contributes to Focal Adhesion Size, Membrane Protrusion and Cell Migration
Short Talk: Miro1-Mediated Mitochondrial Distribution Contributes to Focal Adhesion Size, Membrane Protrusion and Cell Migration
19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.
08:00—11:00
Mitochondria Biogenesis in Health and Disease
*
Andrew G. Dillin,
University of California, Berkeley, USA
Mitochondria and Protein Folding and Aging
Mitochondria and Protein Folding and Aging
Orian S. Shirihai,
University of California, Los Angeles, USA
Nutrient Interaction with the Mitochondrial Motility Apparatus Regulate Mitochondrial Dynamics
Nutrient Interaction with the Mitochondrial Motility Apparatus Regulate Mitochondrial Dynamics
Giovanni Manfredi,
Weill Medical College of Cornell University, USA
Mitochondrial Involvement in Amyotrophic Lateral Sclerosis
Mitochondrial Involvement in Amyotrophic Lateral Sclerosis
L. Stirling Churchman,
Harvard Medical School, USA
Short Talk: Synchronized Translation Programs across Cellular Compartments during Mitochondrial Biogenesis
Short Talk: Synchronized Translation Programs across Cellular Compartments during Mitochondrial Biogenesis
11:00—12:00
Meet the Editors
*
Jodi Nunnari,
University of California, Davis, USA
Nancy R. Gough,
National Breast Cancer Coalition, USA
Alexia-Ileana Zaromytidou,
Nature Cancer, USA
Petra Gross,
Journal of Cell Science, UK
Andrea Leibfried,
EMBO Journal, Germany
Sadaf Shadan,
Nature, UK
Nick Fulcher,
Nature Protocols, UK
17:00—19:15
Mitochondria as Signaling Platforms
Nika N. Danial,
Dana-Farber Cancer Institute, USA
Mitochondria and Energy Metabolism in Disease States
Mitochondria and Energy Metabolism in Disease States
*
Heidi M. McBride,
McGill University, Canada
A Role of Mitochondria in Peroxisomal Biogenesis
A Role of Mitochondria in Peroxisomal Biogenesis
Sebastien Herzig,
The Salk Institute for Biological Studies, USA
Hilla Weidberg,
University of British Columbia, Canada
Short Talk: A Surprising Role for the Multidrug Resistance Response During Mitochondrial Protein Import Stress
Short Talk: A Surprising Role for the Multidrug Resistance Response During Mitochondrial Protein Import Stress
Heather Weir,
Harvard T. H. Chan School of Public Health, USA
Short Talk: Mitochondrial Plasticity is Required for AMPK-Mediated Longevity
Short Talk: Mitochondrial Plasticity is Required for AMPK-Mediated Longevity
19:15—20:15
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.
08:00—11:00
Mitochondrial Regulation and Cell Death
Ana J. García-Sáez,
University of Tübingen, Germany
Mitochondrial Permeabilization by Bax at the Single Molecule Level
Mitochondrial Permeabilization by Bax at the Single Molecule Level
Siegfried Hekimi,
McGill University, Canada
No Evidence that Mitochondrial Dysfunction Causes Animal Aging
No Evidence that Mitochondrial Dysfunction Causes Animal Aging
*
Stefan Jakobs,
Max Planck Institute for Biophysical Chemistry, Germany
Super-Resolution Microscopy of Bax-Mediated MOMP
Super-Resolution Microscopy of Bax-Mediated MOMP
Suzanne Hoppins,
University of Washington, USA
Bax and Mitochondrial Dynamics
Bax and Mitochondrial Dynamics
Isabella Straub,
Montreal Neurological Institute-McGill University, Canada
Short Talk: The Role of the Mitochondrial Protein CHCHD10 in Neurodegenerative Disorders
Short Talk: The Role of the Mitochondrial Protein CHCHD10 in Neurodegenerative Disorders
17:00—19:00
Mitochondrial Quality Control
Richard J. Youle,
NINDS, National Institutes of Health, USA
Ubiquitin Signals on Mitochondria Promote Mitophagy via Autophagy Receptors
Ubiquitin Signals on Mitochondria Promote Mitophagy via Autophagy Receptors
*
Anu Suomalainen Wartiovaara,
University of Helsinki, Finland
Neural Pathophysiology upon Mitochondrial Disease
Neural Pathophysiology upon Mitochondrial Disease
Hong Xu,
NHLBI, National Institutes of Health, USA
Translational Regulation of mtDNA Replication and Selection during Drosophila Oogenesis
Translational Regulation of mtDNA Replication and Selection during Drosophila Oogenesis
Marta Vranas,
McGill University, Canada
Short Talk: The Structural Basis for Parkin-Mediated Mitochondrial Quality Control
Short Talk: The Structural Basis for Parkin-Mediated Mitochondrial Quality Control
19:15—20:15
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.
20:00—23:00
Entertainment
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.
*Session Chair †Invited, not yet responded.
We gratefully acknowledge support for this conference from:
Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
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We gratefully acknowledge additional support for this conference from:
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We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:
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Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:
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Symposia, please contact: Sarah Lavicka,
Director of Corporate Relations, Email: sarahl@keystonesymposia.org, Phone:+1 970-262-2690 Click here for more information on Industry Support and Recognition Opportunities. If you are interested in becoming an advertising/marketing in-kind partner, please contact: Nick Dua, Senior Director, Communications, Email: nickd@keystonesymposia.org, Phone:+1 970-262-1179 |
