Keystone Symposia

China World Hotel Floorplan

This meeting took place in 2015



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Human Nutrition, Environment and Health (T1)


Organizer(s) Martin Kussmann, Hannelore Daniel and Jacqueline Pontes Monteiro
October 14—18, 2015
China World Hotel • Beijing, China
Discounted Abstract Deadline: Jun 16, 2015
Abstract Deadline: Jul 14, 2015
Scholarship Deadline: Jun 16, 2015
Discounted Registration Deadline: Sep 10, 2015

Organized in collaboration with BGI. Sponsored by Nestlé Institute of Health Sciences. Part of the Keystone Symposia Global Health Series, supported by the Bill & Melinda Gates Foundation.

Summary of Meeting:
Diet is the most important environmental factor for maintaining health and preventing disease. The increasing incidence of complex, age-related chronic diseases, as well as the ongoing prevalence of malnutrition, is fueling scientific, ethical and economic calls for intensifying and improving translational health care research. Understanding the interactions of nutrition and lifestyle with an individual’s genetic makeup is a necessary first step to developing strategies to prevent or delay metabolic and cognitive decline and to complement the reactive approach of using pharmaceuticals to treat symptoms. Translational research to maintain health and prevent and/or delay disease onset requires an interdisciplinary systems approach that embraces complexity of human individuality in a rapidly changing environment. Nutrigenomics overarches this theme by investigating how genomic and epigenomic individuality predisposes to dietary response, health and disease and how an individual’s genome expresses itself at different omic levels (proteomics, metabonomics, lipidomics) in response to environment, including nutrition. Molecular phenotyping of humans over time and across healthy and safe exposures and challenges represents a new research strategy that begins to embrace nutritional, environmental, genomic, microbiological and epidemiological competencies and will thereby challenge more classical nutritional approaches. At the same time, nutrition is advancing from a rather reductionist and descriptive approach to a more quantitative, systems-level science. The goals and outcomes of this meeting include: 1) Bringing together researchers from traditionally rather separated disciplines: nutrition, (gen)omics, clinics, physiology, epidemiology, analytics, biomathematics; 2) Advancing nutrition research as a quantitative, holistic and molecular science; 3) Reviewing/challenging classical pre-clinical models and clinical study designs and incorporating improved translational in vitro and in vivo models, human intervention study designs, and innovative new tools/technologies for molecular phenotyping and capture of human diet and lifestyle; and 4) Connecting basic laboratory science to patient- and consumer-relevant outputs in terms of personalized dietary/nutritional counseling and monitoring/diagnostics.

View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


The meeting will begin on Wednesday, October 14 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Sunday, October 18 with a closing plenary session from 17:00 to 19:00, followed by a social hour. We recommend return travel on Monday, October 19 in order to fully experience the meeting.

WEDNESDAY, OCTOBER 14

16:00—20:00
Arrival and Registration

Grand Ballroom Foyer
18:00—20:00
Networking and Welcome Mixer
No registration fees are used to fund alcohol served at this function.

Grand Ballroom Foyer

THURSDAY, OCTOBER 15

08:00—09:00
Breakfast

Individual Hotel
09:00—10:00
Welcome and Keynote Address

Conference Hall A
* Martin Kussmann, Nuritas Ltd., Ireland
Session Chair

* Jacqueline Pontes Monteiro, Universidade de São Paulo, Brazil
Session Chair

* Hannelore Daniel, Technische Universität München, Germany
Session Chair

José M. Ordovás, Tufts University, USA
Human Health, Genes and Diet

10:00—12:15
The Interaction between Human Genome, Diet and Environment

Conference Hall A
* Martin Kussmann, Nuritas Ltd., Ireland
Session Chair

Claudio Franceschi, University of Bologna, Italy
Genes and Environment for Human Longevity

Leroy E. Hood, Institute for Systems Biology, USA
Systems Medicine and Proactive P4 Medicine: Transforming Healthcare and Nutrition through Wellness

Liping Zhao, Shanghai Jiao Tong University, China and Rutgers University, USA
Dietary Modulation of Gut Microbiota for Obesity Management: From Association to Causation to Translation

Alexander M. Vaiserman, Institute of Gerontology, Ukraine
Short Talk: Developmental Nutritional Programming of Type 2 Diabetes: Evidence from the Ukraine Famine of 1932-1933

10:40—11:00
Coffee Break

Conference Hall Foyer
12:15—13:00
Poster Setup

Conference Hall B
13:00—22:00
Poster Viewing

Conference Hall B
12:15—17:00
On Own for Lunch

16:30—17:00
Coffee Available

Conference Hall Foyer
17:00—19:00
Translational Models for Human Nutrition and Health

Conference Hall A
* Kendal Hirschi, Baylor College Medicine, USA
Session Chair

Vijayalakshmi Varma, National Center for Toxicological Research, FDA, USA
Adipocyte Responses to Fructose: A Characterization Using Systems Biology Approaches

Aldons J. Lusis, University of California, Los Angeles, USA
Systems Genetics Analysis of Host-Gut Microbiota Interactions

Patrick J. Stover, Cornell University, USA
In Search of a Common Pathway for Folic Acid-Responsive Neural Tube Defects, Neurodegeneration and Cancer

Sumei Hu, Institute of Food and Health, University College Dublin, Ireland
Short Talk: The Impact of Milk Derived Bioactives on Glycemic Management

19:00—20:00
Networking Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Conference Hall B
19:30—22:00
Poster Session 1

Conference Hall B

FRIDAY, OCTOBER 16

08:00—09:00
Breakfast

Individual Hotel
09:00—12:15
Human Nutritional and Lifestyle Interventions

Conference Hall A
* Patrick J. Stover, Cornell University, USA
Session Chair

Hannelore Daniel, Technische Universität München, Germany
Characterising Normal Human Metabolism

Ben van Ommen, TNO, Netherlands
Diet, Systems Flexibility and My Optimal Health

Jacqueline Pontes Monteiro, Universidade de São Paulo, Brazil
The Genomics of Micronutrient Requirements

Robert Zeigler, IRRI, USA
Rice as a Tool to Improve Nutrition for the World's Poor

Marie-Pier Scott-Boyer, University of Trento COSBI, Italy
Short Talk: Network-Based Analysis of Cofactor-Protein Interactions in Nutrition and Complex Diseases

Namita Parikshit Mahalle, Deenanath Mangeshkar Hospital and Research Center, India
Short Talk: A Study of Nutritional Factors and its Relation with Insulin Resistance and Inflammatory Markers in Patients with Coronary Artery Disease in Indian Population

10:20—10:40
Coffee Break

Conference Hall Foyer
12:15—17:00
Poster Viewing

Conference Hall B
12:15—17:00
On Own for Lunch

16:30—17:00
Coffee Available

Conference Hall Foyer
17:00—19:00
Capturing and Monitoring Human Individuality

Conference Hall A
* Chris Evelo, Maastricht University, Netherlands
Session Chair

Qiang Tian, , USA
Wellness, Diseases and P4 Medicine

Rui Chen, Stanford University, USA
Longitudinal Omics in Humans

Rick Weiss, Viocare, Inc, USA
Self-Monitoring of Diet and Lifestyle

Karsten Hiller, Technische Universität Braunschweig, Germany
Short Talk: Combining Dried Blood Spots with Stable-Isotope Tracers to Profile Dynamics of Glucose Metabolism in Human Subjects

19:00—20:00
Networking Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Conference Hall B

SATURDAY, OCTOBER 17

08:00—09:00
Breakfast

Individual Hotel
09:00—12:00
From Nutrigenomics to Systems Nutrition

Conference Hall A
* Jim Kaput, Nestlé Institute of Health Sciences, Switzerland
Session Chair

Martin Kussmann, Nuritas Ltd., Ireland
Omics-Rooted Systems Studies of Human Phenotypes

Lorraine Brennan, University College Dublin, Ireland
Metabotyping in Nutrition Research

Marijana Radonjic, EdgeLeap, Netherlands
From Disconnected Data to Emerging Insights: Unraveling Complexity of Food-Health Interactions

Paloma K. Barrera, INMEGEN, Mexico
Short Talk: Antioxidant-Related Gene Expression Changes by Cocoa Polyphenols Intake

Xiaojie Tan, Waters, China
Short Talk: Markers of Health: Molecular Phenotyping Unveils the Healthy Biosignature of “Omega-3” Transgenic Mice

10:20—10:40
Coffee Break

Conference Hall Foyer
13:00—22:00
Poster Viewing

Conference Hall B
12:00—17:00
On Own for Lunch

16:30—17:00
Coffee Available

Conference Hall Foyer
17:00—19:00
Nutrition 2.0 - Translation into Solutions for Human Health

Conference Hall A
* Jacqueline Pontes Monteiro, Universidade de São Paulo, Brazil
Session Chair

Juan B. Ochoa Gautier, Nestle Health Science S1216, USA
Personalized Nutrition in Critical Care

Xu Lin, Shanghai Institutes for Biological Sciences Chinese Academy of Sciences, China
Genetic Variants, Nutrient-Related Biomarkers on Metabolic Diseases in Chinese

Maria-Carlota Dao, Institute of Cardiometabolism and Nutrition, ICAN, France
Gut Microbiota and Cardiometabolic Risks

Michael Fenech, CSIRO Food and Nutrition, Australia
Short Talk: Plasma Micronutrient Levels and Telomere Length in Children

19:00—20:00
Networking Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Conference Hall B
19:30—22:00
Poster Session 2

Conference Hall B

SUNDAY, OCTOBER 18

08:00—09:00
Breakfast

Individual Hotel
09:00—10:10
Global Nutrition and Sustainability

Conference Hall A
* Ben van Ommen, TNO, Netherlands
Session Chair

Jim Kaput, Nestlé Institute of Health Sciences, Switzerland
Enabling Nutrient Security and Sustainability through Systems Research

Nina V. Fedoroff, Pennsylvania State University, USA
The Safety, Nutritional Value, and Sustainability of Organically and Conventionally Grown Food

10:10—10:30
Coffee Break

Conference Hall Foyer
10:30—12:00
Panel Discussion: Perspectives and Needs for research in the Food, Diet and Health Relationship

Conference Hall A
* Martin Kussmann, Nuritas Ltd., Ireland
Session Chair

Jim Kaput, Nestlé Institute of Health Sciences, Switzerland

Ben van Ommen, TNO, Netherlands

Lorraine Brennan, University College Dublin, Ireland

Claudio Franceschi, University of Bologna, Italy

12:00—12:15
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)

Grand Ballroom A
12:15—14:00
Networking Lunch

Conference Hall B
14:00—16:00
Workshop

Conference Hall A
* Jacqueline Pontes Monteiro, Universidade de São Paulo, Brazil
Session Chair

G. Bhanuprakash Reddy, National Institute of Nutrition, India
Influence of Micronutrients on Biochemical Pathways Involved in Diabetic Complications

Padmapriyadarsini Chandrasekaran, National Institute for Research in Tuberculosis, India
Dietary Intake, Nutritional Status and Relationship to Serum Lipids among Antiretroviral Naïve HIV-Infected Children in South India

Neil A. Hanchard, National Human Genome Research Institute, NIH, USA
Dna Methylation Changes in Severe Childhood Malnutrition

Shuxin Han, Case Western Reserve University, USA
Circadian Control of Bile Acid Synthesis by a KLF15-Fgf15 Axis

Efrat Monsonego Ornan, Hebrew University of Jerusalem, Israel
Nutritional Aspects of Skeletal Development

Abena S. Amoah, Noguchi Memorial Institute for Medical Research, Ghana
Breastfeeding Duration and Asthma in Urban Schoolchildren in Ghana

Edwin Andres Higuita, Corporación Universitaria Remington, Colombia
Immunomodulation of T Cells Subpopulations and NK Cells in Elderly Adults during a 12 Weeks Intervention with a Nutritional Complement Enriched with Biotechnologically Ganoderma lucidum Extracted Beta Gluc

Pieter Johan Giesbertz, Technische Universität München, Germany
Metabolomic Signatures of Obesity and Diabetes Revealed in Corresponding Genetic Mouse Models

16:30—17:00
Coffee Available

China World Summit Wing – Summit Ballroom, Level 3
17:00—19:00
Joint Session with Grand Challenges and Keystone Symposia

China World Summit Wing – Summit Ballroom, Level 3
Godfrey Oakley, Emory University, USA
Epidemic Folic Acid Preventable Spina Bifida and Anencephaly--Important Preventable Contribution to Perinatal, Neonatal, Infant and Under 5 Child Mortality

Daniel L. Marks, Oregon Health & Science University, USA
A Comprehensive Approach to Healthy Birth, Growth and Development

19:00—22:00
Social Hour with Grand Challenges and Keystone Symposia
No registration fees are used to fund alcohol served at this function.

China World Summit Wing -- Kowloon Ballroom, Level 4

MONDAY, OCTOBER 19

11:00—11:00
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



Keystone Symposia thanks our Sponsors(s) for generously supporting this meeting:

BGI Bill & Melinda Gates Foundation
Nestlé Institute of Health Sciences
 

We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1R13HD085739-01

Funding for this conference was made possible (in part) by Grant, 1 R13 HD 085739 - 01, from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.


We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

360zhyx.com Applied and Translational Genomics
Genes & Nutrition (published by Springer)
 

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: John Monson, Director of Corporate Relations, Email: johnm@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
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Phone:+1 970-262-1179