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This meeting took place in 2016
Here are the related meetings in 2020:
MEETING CANCELLED: Neuro-Immune Interactions in the Central Nervous System (Z5)
For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.
Microglia in the Brain (Z4)
Organizer(s) Beth Stevens and Richard M. Ransohoff
June 12—16, 2016
Keystone Resort • Keystone, CO USA
Discounted Abstract Deadline: Feb 11, 2016
Abstract Deadline: Mar 10, 2016
Scholarship Deadline: Feb 11, 2016
Discounted Registration Deadline: Apr 12, 2016
Sponsored by BioLegend, Inc., Ionis Pharmaceuticals, Inc. and Merck & Co., Inc.
Joint Meeting:
Common Mechanisms of Neurodegeneration (Z3)
Summary of Meeting:
In the past five years, understanding of the origins and functions of microglia, the unique myeloid cells of the central nervous system (CNS) parenchyma, has proceeded at such a remarkable pace that it’s as if an entirely new CNS cell type had been discovered. Since their discovery 100 years ago, it has been suspected that microglia are implicated in virtually all disorders of the nervous system. Associations of polymorphic variants of microglial genes have now proven this hypothesis. It is therefore rather urgent to engage investigators in developing a coherent account of the present status of microglial origins, physiological functions and aberrant properties in the diseased CNS. This meeting will further the objective of translating new information into research and treatment strategies. In many ways, the salient barriers in the field can be addressed by sharing fundamental understanding of complex organ systems among investigators. Microglial research is now conducted in parallel among three disciplines: leukocyte biology, neuroscience and immunology. Other interested research groups include those studying neurodegeneration; developmental neurological disorders (autism, schizophrenia); aging; neuroimmune disorders; and stroke and brain trauma. Optimal progress can only be realized by bringing together thought leaders and students in these varied disciplines around the common goal of studying how microglia are involved in processes under investigation. The program will incorporate the extraordinary depth and breadth of scientists now examining microglial biology and will highlight cutting-edge imaging and genetic technologies.
View Scholarships/Awards
In the past five years, understanding of the origins and functions of microglia, the unique myeloid cells of the central nervous system (CNS) parenchyma, has proceeded at such a remarkable pace that it’s as if an entirely new CNS cell type had been discovered. Since their discovery 100 years ago, it has been suspected that microglia are implicated in virtually all disorders of the nervous system. Associations of polymorphic variants of microglial genes have now proven this hypothesis. It is therefore rather urgent to engage investigators in developing a coherent account of the present status of microglial origins, physiological functions and aberrant properties in the diseased CNS. This meeting will further the objective of translating new information into research and treatment strategies. In many ways, the salient barriers in the field can be addressed by sharing fundamental understanding of complex organ systems among investigators. Microglial research is now conducted in parallel among three disciplines: leukocyte biology, neuroscience and immunology. Other interested research groups include those studying neurodegeneration; developmental neurological disorders (autism, schizophrenia); aging; neuroimmune disorders; and stroke and brain trauma. Optimal progress can only be realized by bringing together thought leaders and students in these varied disciplines around the common goal of studying how microglia are involved in processes under investigation. The program will incorporate the extraordinary depth and breadth of scientists now examining microglial biology and will highlight cutting-edge imaging and genetic technologies.
View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference
The meeting will begin on Sunday, June 12 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, June 16 with a closing plenary session and keynote address from 17:00 to 19:00, followed by a social hour and entertainment. We recommend return travel on Friday, June 17 in order to fully experience the meeting.
SUNDAY, JUNE 12
MONDAY, JUNE 13
TUESDAY, JUNE 14
WEDNESDAY, JUNE 15
THURSDAY, JUNE 16
FRIDAY, JUNE 17
Conference Program Print | View meeting in 12 hr (am/pm) time
The meeting will begin on Sunday, June 12 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, June 16 with a closing plenary session and keynote address from 17:00 to 19:00, followed by a social hour and entertainment. We recommend return travel on Friday, June 17 in order to fully experience the meeting.
SUNDAY, JUNE 12
18:00—20:00
Welcome Mixer
No registration fees are used to fund alcohol served at this function.
08:30—09:30
Welcome and Keynote Address
*
Beth Stevens,
Boston Children's Hospital, Harvard Medical School, USA
Christopher K. Glass,
University of California, San Diego, USA
The Nature and Nurture of Macrophage Identity and Function
The Nature and Nurture of Macrophage Identity and Function
08:30—09:30
Welcome and Keynote Address
*
Bradley T. Hyman,
Massachusetts General Hospital, USA
Laura Ranum,
University of Florida, USA
Repeat Associated Non-ATG (RAN) Translation: New Starts and Directions in Neurologic Disease
Repeat Associated Non-ATG (RAN) Translation: New Starts and Directions in Neurologic Disease
09:30—12:15
Genetics to Pathogenesis
*
Richard M. Ransohoff,
Third Rock Ventures, USA
Zbigniew K. Wszolek,
Mayo Clinic College of Medicine, USA
Adult-Onset Leukoencephalopathy with Axonal Spheroids and Pigmented Glia due to CSF1R gene Mutations: Clinical, Radiological, Pathological and Genetic Correlations
Adult-Onset Leukoencephalopathy with Axonal Spheroids and Pigmented Glia due to CSF1R gene Mutations: Clinical, Radiological, Pathological and Genetic Correlations
Coffee Break
Steven G. Younkin,
Mayo Clinic Jacksonville, USA
Association of Variants in Microglial Genes with Neurodegenerative Disease
Association of Variants in Microglial Genes with Neurodegenerative Disease
Karel Otero Gutierrez,
EISAI, USA
Investigating the Functions of TREM2 in Neurodegeneration
Investigating the Functions of TREM2 in Neurodegeneration
Michael W. Salter,
Hospital for Sick Children and University of Toronto, Canada
Sexual Dimorphism in Microglia-Neuron Signaling in Pain Neuroplasticity
Sexual Dimorphism in Microglia-Neuron Signaling in Pain Neuroplasticity
09:30—11:45
Prions and “Prionoid” Molecules
Beat H. Meier,
ETH Zürich, Switzerland
Atomic-Resolution Structures of Amyloids: HET-s and Different Polymorphs of Amyloid Beta: What Can We Learn?
Atomic-Resolution Structures of Amyloids: HET-s and Different Polymorphs of Amyloid Beta: What Can We Learn?
Coffee Break
*
Adriano M. Aguzzi,
University Hospital of Zürich, Switzerland
Prion Toxicity
Prion Toxicity
Tuomas Knowles,
University of Cambridge, UK
Kinetics of Protein Aggregation
Kinetics of Protein Aggregation
Kristen Anne Davenport,
Colorado State University, USA
Short Talk: Dissecting the Role of the PrP Amino Terminus in Species Barriers
Short Talk: Dissecting the Role of the PrP Amino Terminus in Species Barriers
17:00—19:15
Microglia Surveillance in Real Time: Lessons from in vivo Imaging
*
Marie-Ève Tremblay,
Laval University, Canada
David Attwell,
University College London, UK
An Ion Channel Regulating Microglial Surveillance of the Brain Parenchyma
An Ion Channel Regulating Microglial Surveillance of the Brain Parenchyma
Dimitrios Davalos,
Lerner Research Institute, Cleveland Clinic, USA
Microglial Responses to Blood Brain Barrier Breakdown
Microglial Responses to Blood Brain Barrier Breakdown
Francesca Peri,
European Molecular Biology Laboratory, Germany
Microglia Go Live: The Role Neuronal-Microglial Interactions in the Development and Repair of the CNS
Microglia Go Live: The Role Neuronal-Microglial Interactions in the Development and Repair of the CNS
Courtney N. Easley-Neal,
Eisai, USA
Short Talk: Cerebral Cortex Targeted Depletion of Microglia, via CSF1R Ligand Inhibition, as a Potential Approach to Mitigate Neurodegeneration in Alzheimer’s Disease
Short Talk: Cerebral Cortex Targeted Depletion of Microglia, via CSF1R Ligand Inhibition, as a Potential Approach to Mitigate Neurodegeneration in Alzheimer’s Disease
Deborah Kurrasch,
University of Calgary, Canada
Short Talk: Microglia Influence Embryonic Development of Hypothalamic Energy Balance Centers
Short Talk: Microglia Influence Embryonic Development of Hypothalamic Energy Balance Centers
17:00—19:00
Protein Templating and Spread of Neuropathology
Mathias Jucker,
Hertie-Institute for Clinical Brain Research and DZNE, Germany
Proteopathic Seeds in Neurodegenerative Diseases
Proteopathic Seeds in Neurodegenerative Diseases
*
Bradley T. Hyman,
Massachusetts General Hospital, USA
Neuroanatomy and Consequences of Pathological Propagation in Neurodegeneration
Neuroanatomy and Consequences of Pathological Propagation in Neurodegeneration
Virginia M. Y. Lee,
University of Pennsylvania School of Medicine, USA
New Tauopathy Mouse Models for Alzheimer’s Disease
New Tauopathy Mouse Models for Alzheimer’s Disease
19:15—20:15
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.
08:30—11:30
Synaptic Pruning and Plasticity
*
Staci Bilbo,
Duke University, USA
Dorothy Schafer,
University of Massachusetts Medical School, USA
Microglia: Dynamic Sensors of Neural Activity and Regulators of Brain Plasticity
Microglia: Dynamic Sensors of Neural Activity and Regulators of Brain Plasticity
Rosa C. Paolicelli,
University of Lausanne, Switzerland
TDP-43 Loss in Microglia Promotes Phagocytosis and affects Synaptic Pruning and Motor Behavior in Adult Mice
TDP-43 Loss in Microglia Promotes Phagocytosis and affects Synaptic Pruning and Motor Behavior in Adult Mice
Coffee Break
Brian MacVicar,
University of British Columbia, Canada
Synaptic Sensing and Modulation by Microglia
Synaptic Sensing and Modulation by Microglia
Ryuta Koyama,
University of Tokyo, Japan
Short Talk: Fever Activates Microglia to Engulf Inhibitory Synapses in Epilepsy
Short Talk: Fever Activates Microglia to Engulf Inhibitory Synapses in Epilepsy
Ukpong B. Eyo,
Mayo Clinic, USA
Short Talk: Bi-Directional Microglial-Neuronal Interactions During Glutamate-Induced Hyperactivity
Short Talk: Bi-Directional Microglial-Neuronal Interactions During Glutamate-Induced Hyperactivity
08:30—11:45
New Treatment Modalities
Christer Nordstedt,
Eli Lilly and Company, USA
Future Alzheimer's Therapeutics
Future Alzheimer's Therapeutics
*
Nathalie Isabelle Cartier-Lacave,
CEA MIRCen, France
Gene Therapy Strategy for Alzheimer’s Disease: The Cholesterol Connection
Gene Therapy Strategy for Alzheimer’s Disease: The Cholesterol Connection
Coffee Break
Douglas Golenbock,
University of Massachusetts Medical School, USA
The Inflammasome Product IL18 Prevents Amyloid-Induced Fatal Seizures
The Inflammasome Product IL18 Prevents Amyloid-Induced Fatal Seizures
Fyodor D. Urnov,
University of California, Berkeley, USA
Targeted Genome Regulation for Neurodegenerative Disease Therapy
Targeted Genome Regulation for Neurodegenerative Disease Therapy
Claire E. Le Pichon,
NICHD, National Institutes of Health, USA
Short Talk: Loss of Dual Leucine Zipper Kinase Signaling is Protective in the SOD1 Mouse Model of ALS
Short Talk: Loss of Dual Leucine Zipper Kinase Signaling is Protective in the SOD1 Mouse Model of ALS
William J. Meilandt,
Genentech, inc., USA
Short Talk: Loss of Dual Leucine Zipper Kinase Signaling is Protective in the PS2APP Mouse Model of Alzheimer’s Disease
Short Talk: Loss of Dual Leucine Zipper Kinase Signaling is Protective in the PS2APP Mouse Model of Alzheimer’s Disease
14:30—15:30
Workshop 1: Ontogeny and Development
*
Florent Ginhoux,
Singapore Immunology Network, Singapore
Modeling Microglial Differentiation and Function in vitro using Induced Pluripotent Stem Cells
Modeling Microglial Differentiation and Function in vitro using Induced Pluripotent Stem Cells
Morgane S. Thion,
INSERM U1024, France
In utero Development of Microglia: Intrinsic Programs and Impact of Microbiota
In utero Development of Microglia: Intrinsic Programs and Impact of Microbiota
Xianhua Piao,
University of California San Francisco, USA
Microglial Transglutaminase-2 (TG2) Regulates Oligodendrocyte Development and CNS Myelination through GPR56 Signaling
Microglial Transglutaminase-2 (TG2) Regulates Oligodendrocyte Development and CNS Myelination through GPR56 Signaling
Huixin Xu,
Boston Children's Hospital, USA
Environmental Enrichment Potently Prevents Microglia-Mediated Neuroinflammation by Human Amyloid Beta-Protein Oligomers
Environmental Enrichment Potently Prevents Microglia-Mediated Neuroinflammation by Human Amyloid Beta-Protein Oligomers
15:30—16:30
Workshop 2: Models and Techniques I
*
Dimitrios Davalos,
Lerner Research Institute, Cleveland Clinic, USA
Steven Marinero,
Duke University, USA
3D Brain Tissue-Based Model for Probing Contributions of Microglia and Peripheral Macrophages in Driving Neurodegenerative Disease Mechanisms
3D Brain Tissue-Based Model for Probing Contributions of Microglia and Peripheral Macrophages in Driving Neurodegenerative Disease Mechanisms
Susanna Rosi,
University of California, San Francisco, USA
In vivo Metabolic Imaging of Neuroinflammation after TBI
In vivo Metabolic Imaging of Neuroinflammation after TBI
Santiago Sole Domenech,
Weill Cornell Medicine, USA
Intravital Imaging of Acidic Compartments in Mouse Brain Microglia
Intravital Imaging of Acidic Compartments in Mouse Brain Microglia
17:00—19:00
Role in Neurodevelopmental and Neuropsychiatric Disorders
*
Dorothy Schafer,
University of Massachusetts Medical School, USA
Staci Bilbo,
Duke University, USA
Modulation of Microglia by Maternal Immune Activation: Relevance for Autism
Modulation of Microglia by Maternal Immune Activation: Relevance for Autism
Mario R. Capecchi,
University of Utah, USA
A Causal Role for Defective Microglia in the OCD-Spectrum Disorder, Trichotillomania
A Causal Role for Defective Microglia in the OCD-Spectrum Disorder, Trichotillomania
Beth Stevens,
Boston Children's Hospital, Harvard Medical School, USA
Microglia Function and Dysfunction During Brain Wiring
Microglia Function and Dysfunction During Brain Wiring
17:00—19:00
Role of Glia
*
Don W. Cleveland,
University of California, San Diego, USA
Mechanism and Therapy in ALS and Beyond
Mechanism and Therapy in ALS and Beyond
Shane Antony Liddelow,
New York University Langone Medical Center, USA
What Do Reactive Astrocytes Do?
What Do Reactive Astrocytes Do?
Serge Przedborski,
Columbia University, USA
Molecular Mechanism of Motor Neuron Degeneration in Amyotrophic Lateral Sclerosis
Molecular Mechanism of Motor Neuron Degeneration in Amyotrophic Lateral Sclerosis
Brian V. Lananna,
University of Washington in St. Louis, USA
Short Talk: The Astrocyte Circadian Clock Regulates Astrogliosis and Neuronal Injury
Short Talk: The Astrocyte Circadian Clock Regulates Astrogliosis and Neuronal Injury
08:30—09:15
Special Lecture
09:15—11:30
Microglia in Aging and Neurodegenerative Disease
*
Thomas Möller,
Foundational Neuroscience Center, USA
Marie-Ève Tremblay,
Laval University, Canada
Dark Microglia: A New Phenotype Predominantly Associated with Pathological States
Dark Microglia: A New Phenotype Predominantly Associated with Pathological States
Coffee Break
Gary E. Landreth,
Case Western Reserve University, USA
Nuclear Receptors License the Phagocytic Clearance of Amyloid by Plaque-Associated Macrophages from the AD Brain
Nuclear Receptors License the Phagocytic Clearance of Amyloid by Plaque-Associated Macrophages from the AD Brain
Daniel Wilton,
Boston Children’s Hospital, Harvard Medical School, USA
Short Talk: Microglia Mediate Early Loss of Specific Synaptic Connections in Huntington's Disease
Short Talk: Microglia Mediate Early Loss of Specific Synaptic Connections in Huntington's Disease
Michelle K. Cahill,
University of California, San Francisco, USA
Short Talk: Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation
Short Talk: Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation
08:30—11:30
RNA and New Mechanisms of Toxicity
J. Paul Taylor,
St. Jude Children's Research Hospital, USA
Disturbed Phase Transitions Underlie Most Forms of ALS and FTD
Disturbed Phase Transitions Underlie Most Forms of ALS and FTD
Eva-Maria Hock,
University of Zürich, Switzerland
Short Talk: Understanding the Involvement of Cellular Stress in the Initiation of TDP-43 and FUS Pathology in Slice Culture Models
Short Talk: Understanding the Involvement of Cellular Stress in the Initiation of TDP-43 and FUS Pathology in Slice Culture Models
Maurice S. Swanson,
University of Florida, USA
Dynamic Mutations and RNA-Mediated Disease Mechanisms
Dynamic Mutations and RNA-Mediated Disease Mechanisms
Coffee Break
*
Magdalini Polymenidou,
University of Zürich, Switzerland
The Intertwined Roles of RNA Misregulation and Protein Aggregation in ALS and FTD
The Intertwined Roles of RNA Misregulation and Protein Aggregation in ALS and FTD
Josh Dubnau,
Stony Brook University, USA
Short Talk: The Retrotransposon Storm: Retrotransposon Activation Causes Neurodegeneration in a Drosophila TDP-43 Model of Amyotrophic Lateral Sclerosis
Short Talk: The Retrotransposon Storm: Retrotransposon Activation Causes Neurodegeneration in a Drosophila TDP-43 Model of Amyotrophic Lateral Sclerosis
11:30—12:30
Panel: Career Development in Biotech and Pharma
Adam W. Bero,
Biogen, USA
Irena Kadiu,
UCB BioPharma SPRL, Belgium
Morag Stewart,
VL49, USA
Sean P. Cook,
Teva Pharmaceuticals, USA
Peter S. DiStefano,
Zebra Biologics, Inc, USA
Matthew Kennedy,
Merck Research Labs, USA
17:00—19:00
Profiling Resident Microglia in Health and Disease
*
Marco Prinz,
University of Freiburg, Germany
Shane Antony Liddelow,
New York University Langone Medical Center, USA
Identification of Novel Microglia-Specific Markers in Healthy Mouse Brain
Identification of Novel Microglia-Specific Markers in Healthy Mouse Brain
Joseph El Khoury,
Massachusetts General Hospital, USA
Deep Sequencing Brain Microglia Reveals Unique Molecular Fingerprints
Deep Sequencing Brain Microglia Reveals Unique Molecular Fingerprints
Erik H.W.G.M. Boddeke,
University of Groningen, Netherlands
Human and Mouse Microglia Transcriptomes Related to Neurodegeneration and Aging
Human and Mouse Microglia Transcriptomes Related to Neurodegeneration and Aging
Brad A. Friedman,
Genentech, Inc., USA
Short Talk: The Transcriptional Landscape of Brain Myeloid Cells Reveals Gene Expression Responses Associated with Proliferation, Interferon Signaling and Neurodegeneration
Short Talk: The Transcriptional Landscape of Brain Myeloid Cells Reveals Gene Expression Responses Associated with Proliferation, Interferon Signaling and Neurodegeneration
17:00—19:00
Inflammatory Mechanisms
Gabor Veres,
Bluebird Bio, USA
Clinical Study Update on the Efficacy and Safety of Ex Vivo Gene Therapy with Lenti-D Lentiviral Vector for the Treatment of Cerebral Adrenoleukodystrophy
Clinical Study Update on the Efficacy and Safety of Ex Vivo Gene Therapy with Lenti-D Lentiviral Vector for the Treatment of Cerebral Adrenoleukodystrophy
Richard M. Ransohoff,
Third Rock Ventures, USA
(Re)Introducing Microglia
(Re)Introducing Microglia
Jennifer Lee,
Johns Hopkins University, USA
Hypothermia and Rewarming Activate a White Matter Macroglial Unfolded Protein Response Independent of Hypoxia-Ischemia in a Piglet Model
Hypothermia and Rewarming Activate a White Matter Macroglial Unfolded Protein Response Independent of Hypoxia-Ischemia in a Piglet Model
19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.
08:30—11:45
Microglia Regulation of Pain and Neuronal–Glia Interactions
*
Francesca Peri,
European Molecular Biology Laboratory, Germany
Richard M. Ransohoff,
Third Rock Ventures, USA
The Fractalkine Story: An Update
The Fractalkine Story: An Update
Sonia Garel,
INSERM, France
Microglia and Prenatal Inflammation in the Development of Cortical Inhibitory Circuits
Microglia and Prenatal Inflammation in the Development of Cortical Inhibitory Circuits
Coffee Break
Amanda Sierra,
Achucarro Basque Center for Neuroscience, Spain
Short Talk: Of Ghost Cells and Ravenous Microglia: Coupling between Apoptosis and Microglial Phagocytosis in Health and Disease
Short Talk: Of Ghost Cells and Ravenous Microglia: Coupling between Apoptosis and Microglial Phagocytosis in Health and Disease
Makoto Tsuda,
Kyushu University, Japan
Spinal Microglia Activated by Purinergic Signaling and Neuropathic Pain
Spinal Microglia Activated by Purinergic Signaling and Neuropathic Pain
Tuan Trang,
University of Calgary, Canada
Short Talk: Pain, Poppies, and Pannexin-1 Channels on Microglia
Short Talk: Pain, Poppies, and Pannexin-1 Channels on Microglia
08:30—11:30
Unfolded Proteins
*
Richard I. Morimoto,
Northwestern University, USA
Proteostasis Disruptions in Aging and Neurodegenerative Disease
Proteostasis Disruptions in Aging and Neurodegenerative Disease
David Eisenberg,
University of California, Los Angeles, USA
Structural Studies of Toxic and Non-Toxic Amyloid Proteins
Structural Studies of Toxic and Non-Toxic Amyloid Proteins
Coffee Break
Gordon P. Meares,
West Virginia University, USA
Short Talk: Targeting PERK for Selective Immunomodulation in the CNS
Short Talk: Targeting PERK for Selective Immunomodulation in the CNS
Christoph Gericke,
University of Zurich, Switzerland
Short Talk: The Influence of Alzheimer’s Disease-Like Cerebral Amyloidosis on Brain Immune Surveillance
Short Talk: The Influence of Alzheimer’s Disease-Like Cerebral Amyloidosis on Brain Immune Surveillance
David Christopher Wirthensohn,
University of Cambridge, UK
Short Talk: Detecting and Characterizing Individual Aggregates in Human CSF
Short Talk: Detecting and Characterizing Individual Aggregates in Human CSF
14:30—15:30
Workshop 3: Models and Techniques II
*
Beth Stevens,
Boston Children's Hospital, Harvard Medical School, USA
Julien A. Muffat,
Whitehead Institute for Biomedical Research, USA
Modeling Neuro-Immune Interactions in CNS Disorders using Patient iPS-Derived Microglia-Like Cells
Modeling Neuro-Immune Interactions in CNS Disorders using Patient iPS-Derived Microglia-Like Cells
Ana Badimon,
Mount Sinai School of Medicine, USA
Brain Region Specific Microglia Specification
Brain Region Specific Microglia Specification
Edsel M. Abud,
University of California, Irvine, USA
Generating Microglia from Human iPSCs to Study Alzheimer’s Disease
Generating Microglia from Human iPSCs to Study Alzheimer’s Disease
Petr Tvrdik,
University of Virginia, USA
Imaging and Analysis of Intracellular Calcium Dynamics in Cortical Microglia Responding to Injury
Imaging and Analysis of Intracellular Calcium Dynamics in Cortical Microglia Responding to Injury
15:30—16:30
Brainstorming and Open Discussion
*
Beth Stevens,
Boston Children's Hospital, Harvard Medical School, USA
17:00—18:45
Special Lectures
*
Richard M. Ransohoff,
Third Rock Ventures, USA
Adriano M. Aguzzi,
University Hospital of Zürich, Switzerland
Immunological Aspects of Prion Diseases
Immunological Aspects of Prion Diseases
Thomas Möller,
Foundational Neuroscience Center, USA
Translating Microglial Biology: Promise and Problems
Translating Microglial Biology: Promise and Problems
17:00—18:00
Synaptic Dysfunction in AD, Neurodegenerative Disease, and Developmental Disorders
Tara L. Spires-Jones,
University of Edinburgh, UK
Dynamic Synaptic Alterations Due to Amyloid Beta and Tau
Dynamic Synaptic Alterations Due to Amyloid Beta and Tau
*
Ricardo E. Dolmetsch,
Novartis Institutes for BioMedical Research, USA
Synaptic Alterations as a Drug Target
Synaptic Alterations as a Drug Target
18:00—18:45
Closing Keynote Address
Beth Stevens,
Boston Children's Hospital, Harvard Medical School, USA
How Microglia Prune Specific Synapses in Health & Disease
How Microglia Prune Specific Synapses in Health & Disease
19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.
20:00—23:00
Entertainment
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.
*Session Chair †Invited, not yet responded.
We gratefully acknowledge support for this conference from:
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