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This meeting took place in 2017
Here are the related meetings in 2020:
Inflammation, Microbiota and Cancer (E3)
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Cell Plasticity within the Tumor Microenvironment (A1)
Organizer(s) Sergei Grivennikov, Florian R. Greten and Mikala Egeblad
January 8—12, 2017
Big Sky Resort • Big Sky, MT USA
Discounted Abstract Deadline: Sep 19, 2016
Abstract Deadline: Oct 6, 2016
Scholarship Deadline: Sep 19, 2016
Discounted Registration Deadline: Nov 8, 2016
Sponsored by Journal of Molecular Cell Biology (JMCB) and Roche
Summary of Meeting:
During the last decade, it has become unequivocally evident that tumor development is not a cell-autonomous process but rather depends on the intricate reciprocal interplay of mutant tumor cells with their local and distant environments. Composition and polarization of cells in the tumor microenvironment depends on genetic as well as environmental factors and is directly influenced by tumor therapy. Indeed, therapies that aim to shape the local immune milieu and consecutive signaling pathways in both stromal and tumor/stem cells address the complex pathophysiology of tumors more adequately and may therefore add substantial benefits for therapy. An absolute pre-requisite for such an endeavor is a comprehensive understanding of the exact molecular basis of the complex signaling networks in the tumor microenvironment that control the plasticity of both stromal and tumor cells, thereby shaping the complex cellular contexture, which ultimately forms a pro- or anti-tumorigenic milieu. Thus, this symposium aims to gather a comprehensive functional understanding of mediator-dependent cellular and molecular events that are responsible for the plasticity of both stromal and tumor/stem cells. It will bring together experts in cancer, stromal and immune cells to synthesize scientific knowledge about the phenomenon of cell plasticity within the tumor microenvironment, to define molecular and cellular pathways mediating plasticity and to propose approaches to interfere with cell plasticity for a new generation of effective therapeutic approaches in cancer and chronic injury. Importantly, it will bring together interdisciplinary groups of scientists or investigators who normally would not have an opportunity to meet (classical cancer biologists, tumor immunobiologists, stem cell experts and scientists working on stromal cells).
View Scholarships/Awards
During the last decade, it has become unequivocally evident that tumor development is not a cell-autonomous process but rather depends on the intricate reciprocal interplay of mutant tumor cells with their local and distant environments. Composition and polarization of cells in the tumor microenvironment depends on genetic as well as environmental factors and is directly influenced by tumor therapy. Indeed, therapies that aim to shape the local immune milieu and consecutive signaling pathways in both stromal and tumor/stem cells address the complex pathophysiology of tumors more adequately and may therefore add substantial benefits for therapy. An absolute pre-requisite for such an endeavor is a comprehensive understanding of the exact molecular basis of the complex signaling networks in the tumor microenvironment that control the plasticity of both stromal and tumor cells, thereby shaping the complex cellular contexture, which ultimately forms a pro- or anti-tumorigenic milieu. Thus, this symposium aims to gather a comprehensive functional understanding of mediator-dependent cellular and molecular events that are responsible for the plasticity of both stromal and tumor/stem cells. It will bring together experts in cancer, stromal and immune cells to synthesize scientific knowledge about the phenomenon of cell plasticity within the tumor microenvironment, to define molecular and cellular pathways mediating plasticity and to propose approaches to interfere with cell plasticity for a new generation of effective therapeutic approaches in cancer and chronic injury. Importantly, it will bring together interdisciplinary groups of scientists or investigators who normally would not have an opportunity to meet (classical cancer biologists, tumor immunobiologists, stem cell experts and scientists working on stromal cells).
View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference
The meeting will begin on Sunday, January 8 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, January 12 with a closing plenary session and keynote address from 17:00 to 19:15, followed by a social hour and entertainment. We recommend return travel on Friday, January 13 in order to fully experience the meeting.
SUNDAY, JANUARY 8
MONDAY, JANUARY 9
TUESDAY, JANUARY 10
WEDNESDAY, JANUARY 11
THURSDAY, JANUARY 12
FRIDAY, JANUARY 13
Conference Program Print | View meeting in 12 hr (am/pm) time
The meeting will begin on Sunday, January 8 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, January 12 with a closing plenary session and keynote address from 17:00 to 19:15, followed by a social hour and entertainment. We recommend return travel on Friday, January 13 in order to fully experience the meeting.
SUNDAY, JANUARY 8
18:00—20:00
Welcome Mixer
No registration fees are used to fund alcohol served at this function.
08:00—09:00
Welcome and Keynote Address
*
Sergei Grivennikov,
Fox Chase Cancer Center, USA
*
Florian R. Greten,
Institute for Tumor Biology and Experimental Therapy, Germany
*
Mikala Egeblad,
Cold Spring Harbor Laboratory, USA
Michael Karin,
University of California, San Diego, USA
Tumor-Elicited Inflammation and the Initiation of Colorectal Cancer
Tumor-Elicited Inflammation and the Initiation of Colorectal Cancer
09:00—11:45
Plasticity of Epithelial, Cancer and Stem Cells
*
Cédric Blanpain,
Universite Libre de Bruxelles, Belgium
*
Shelly Peyton,
University of Massachusetts, USA
Florian R. Greten,
Institute for Tumor Biology and Experimental Therapy, Germany
Inflammatory Signaling in Intestinal Stem Cell Plasticity
Inflammatory Signaling in Intestinal Stem Cell Plasticity
John Cassidy,
Cambridge Cancer Genomics, UK
Short Talk: The Development of Tamoxifen Resistance is Linked to Oct4 Driven Transcriptional Plasticity
Short Talk: The Development of Tamoxifen Resistance is Linked to Oct4 Driven Transcriptional Plasticity
Coffee Break
Andrew J. Ewald,
Johns Hopkins University School of Medicine, USA
Phenotypic Plasticity during Cell Invasion and Metastasis
Phenotypic Plasticity during Cell Invasion and Metastasis
Kristiaan Lenos,
Amsterdam Medical Center, Netherlands
Short Talk: Spatiotemporal Regulation of Stem Cell Function in Colon Cancer
Short Talk: Spatiotemporal Regulation of Stem Cell Function in Colon Cancer
Frederic J. de Sauvage,
Genentech, Inc., USA
Targeting Intestinal Stem Cells in Cancer
Targeting Intestinal Stem Cells in Cancer
Brian Bierie,
Whitehead Institute for Biomedical Research, USA
Poster Teaser: Integrin-Beta4 Identifies Cancer Stem Cell-Enriched Populations of Partially-Mesenchymal Carcinoma Cells
Poster Teaser: Integrin-Beta4 Identifies Cancer Stem Cell-Enriched Populations of Partially-Mesenchymal Carcinoma Cells
Jessica L. Christenson,
University of Colorado, USA
Poster Teaser: The Role of the Androgen Receptor in Triple-Negative Breast Cancer Progression: Tumor-Intrinsic and Tumor-Extrinsic Mechanisms
Poster Teaser: The Role of the Androgen Receptor in Triple-Negative Breast Cancer Progression: Tumor-Intrinsic and Tumor-Extrinsic Mechanisms
Ryan Carpenter,
University of Massachusetts, Amherst, USA
Poster Teaser: Capturing Microenvironmental Regulation of Metastatic Dormancy and Recurrence
Poster Teaser: Capturing Microenvironmental Regulation of Metastatic Dormancy and Recurrence
Sara E. Berkey,
University of Pittsburgh, USA
Poster Teaser: The IL17+Foxp3+ and exTh17 Foxp3+ Plastic T Cells Comprise Novel Immunosuppressive Regulatory T Cell Subsets in Tumors
Poster Teaser: The IL17+Foxp3+ and exTh17 Foxp3+ Plastic T Cells Comprise Novel Immunosuppressive Regulatory T Cell Subsets in Tumors
Oxana Dmitrieva-Posocco,
University of Pennsylvania, USA
Poster Teaser: The Role of IL-1R-Signaling in Tumor Elicited Inflammation and Colon Cancer
Poster Teaser: The Role of IL-1R-Signaling in Tumor Elicited Inflammation and Colon Cancer
14:30—16:30
Workshop 1: Plasticity and the Cancer Stem Cell Niche
*
Diana Leigh Avery,
University of Pennsylvania School of Medicine, USA
Matrix Mechanics and Composition Dictate Stromal Cell Differentiation in Lung Tumorigenesis
Matrix Mechanics and Composition Dictate Stromal Cell Differentiation in Lung Tumorigenesis
Ikbale El Ayachi,
University of Tennessee Health Science Center, USA
The Absence of Wnt10b Expression Inhibits Tumor Initiation and Metastasis Modulating Stroma-Tumor Microenvironment Homeostasis
The Absence of Wnt10b Expression Inhibits Tumor Initiation and Metastasis Modulating Stroma-Tumor Microenvironment Homeostasis
*
Loukia Georgiou Karacosta,
Stanford University, USA
Identifying Dynamic EMT Transition States in Lung Cancer Using Single Cell Multidimensional Analysis
Identifying Dynamic EMT Transition States in Lung Cancer Using Single Cell Multidimensional Analysis
Hazel Quinn,
Max Delbruck Centre, Germany
Genetically Interfering with the Tumor Microenvironment via Shh in Wnt-Met driven Mouse Triple Negative Breast Cancer
Genetically Interfering with the Tumor Microenvironment via Shh in Wnt-Met driven Mouse Triple Negative Breast Cancer
Michael Buchert,
Olivia Newton-John Cancer Research Institute, Australia
Insights into the Role of DCLK1 as a Novel Driver of Gastric Cancer
Insights into the Role of DCLK1 as a Novel Driver of Gastric Cancer
Toni Celia-Terrassa,
Princeton University, USA
Pathways Regulating the Evasion of Normal and Cancer Stem Cells from Interferon-Imposed Constraint
Pathways Regulating the Evasion of Normal and Cancer Stem Cells from Interferon-Imposed Constraint
Dejan Maglic,
Relay Therapeutics, USA
The Hedgehog and Hippo Pathways Cooperate in BCC Initiation and Progression
The Hedgehog and Hippo Pathways Cooperate in BCC Initiation and Progression
Hélène Salmon,
Icahn School of Medicine at Mount Sinai, USA
The Tumor Microenvironment Controls Tumor Response to Checkpoint Blockade
The Tumor Microenvironment Controls Tumor Response to Checkpoint Blockade
17:00—19:00
Plasticity and the (Cancer) Stem Cell Niche
*
Florian R. Greten,
Institute for Tumor Biology and Experimental Therapy, Germany
*
Louis Vermeulen,
CEMM, Netherlands
Jing Yang,
University of California, San Diego, USA
Epithelial-Mesenchymal Plasticity in Carcinoma Metastasis
Epithelial-Mesenchymal Plasticity in Carcinoma Metastasis
Cédric Blanpain,
Universite Libre de Bruxelles, Belgium
Skin Tumor Stemness and Progression
Skin Tumor Stemness and Progression
Ekrem Emrah Er,
Memorial Sloan Kettering Cancer Center, USA
Short Talk: Pericytic Spreading of Disseminated Cancer Cells Initiate Multi-Organ Metastasis
Short Talk: Pericytic Spreading of Disseminated Cancer Cells Initiate Multi-Organ Metastasis
Mathias Florian Heikenwälder,
German Cancer Research Center, DKFZ, Germany
Kupffer-Cell Derived TNF Preferentially Triggers Cholangiocellular Carcinoma through JNK under Chronic Mitochondrial Dysfunction and ROS
Kupffer-Cell Derived TNF Preferentially Triggers Cholangiocellular Carcinoma through JNK under Chronic Mitochondrial Dysfunction and ROS
19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.
08:00—11:30
Cell Types Contributing to the Plasticity of the Tumor Microenvironment
*
Jing Yang,
University of California, San Diego, USA
*
Sandra S. McAllister,
Brigham & Women's Hospital/Harvard Medical School, USA
Thomas Tüting,
Otto-von-Guericke University, Germany
Inflammation-Induced Phenotypic Plasticity of Tumor and Immune Cells as a Mechanism of Disease Progression and Therapy Resistance in Melanoma
Inflammation-Induced Phenotypic Plasticity of Tumor and Immune Cells as a Mechanism of Disease Progression and Therapy Resistance in Melanoma
Neta Erez,
Tel Aviv University, Israel
Short Talk: Cancer-Associated Fibroblasts Link Tissue Damage with Tumor-Promoting Inflammation in Breast Cancer
Short Talk: Cancer-Associated Fibroblasts Link Tissue Damage with Tumor-Promoting Inflammation in Breast Cancer
Brian W. Wong,
Washington University School of Medicine, USA
Endothelial versus Cancer Cell Metabolism
Endothelial versus Cancer Cell Metabolism
Coffee Break
Valerie M. Weaver,
University of California, San Francisco, USA
Extracellular Matrix and Tumor Mechanics
Extracellular Matrix and Tumor Mechanics
Shelly Peyton,
University of Massachusetts, USA
Short Talk: Dynamics of Fibronectin Assembly and Tumor Cell Latency
Short Talk: Dynamics of Fibronectin Assembly and Tumor Cell Latency
Raghu Kalluri,
University of Texas MD Anderson Cancer Center, USA
The Functional Role of EMT and Exosomes in Pancreatic Cancer
The Functional Role of EMT and Exosomes in Pancreatic Cancer
Chen Hao Lo,
Moffitt Cancer Center, USA
Poster Teaser: Temporal Dynamics of Macrophage Plasticity in Bone Metastatic Prostate Cancer
Poster Teaser: Temporal Dynamics of Macrophage Plasticity in Bone Metastatic Prostate Cancer
Magdolna Djurec,
Spanish National Cancer Research Center, Spain
Poster Teaser: Reprogramming Cancer Associated Fibroblasts as a Therapeutic Approach against Pancreatic Ductal Adenocarcinoma
Poster Teaser: Reprogramming Cancer Associated Fibroblasts as a Therapeutic Approach against Pancreatic Ductal Adenocarcinoma
Ayse Nihan Kilinc,
University of Basel, Switzerland
Poster Teaser: The Contribution of Epithelial-Mesenchymal Plasticity to Cancer Stemness
Poster Teaser: The Contribution of Epithelial-Mesenchymal Plasticity to Cancer Stemness
Lennart Kester,
Hubrecht Institute, Netherlands
Poster Teaser: Clonal Dynamics with Single Cell Resolution in Different Stages of Colon Carcinoma
Poster Teaser: Clonal Dynamics with Single Cell Resolution in Different Stages of Colon Carcinoma
Natsuko Kimura,
University of Tokyo, Japan
Poster Teaser: Maintenance of Stemness and Niche Environment of Breast Cancer Cells by FRS2beta, a Feedback Inhibitor for HER2-ERK Pathway, during Mammary Tumorigenesis
Poster Teaser: Maintenance of Stemness and Niche Environment of Breast Cancer Cells by FRS2beta, a Feedback Inhibitor for HER2-ERK Pathway, during Mammary Tumorigenesis
17:00—19:00
Plasticity of Immune Cells within the Tumor Microenvironment
*
Mikala Egeblad,
Cold Spring Harbor Laboratory, USA
*
Alana L. Welm,
University of Utah School of Medicine, USA
Peter Friedl,
NCMLS, Radboud University Nijmegen Medical Centre, Netherlands
Serial Killing of Tumor Cells – Impact of the Microenvironment
Serial Killing of Tumor Cells – Impact of the Microenvironment
Giorgio Trinchieri,
NCI, National Institutes of Health, USA
Cancer as a Meta-Organism – Fine-Tuning of Tumor Progression and Response to Therapy by Microbiota-Regulated Immune Cells
Cancer as a Meta-Organism – Fine-Tuning of Tumor Progression and Response to Therapy by Microbiota-Regulated Immune Cells
Melissa A. Meyer,
La Jolla Institute for Immunology, USA
Short Talk: Tumor-Induced IRF8 Deficiency Interrupts BATF3-Dependent Dendritic Cells Development
Short Talk: Tumor-Induced IRF8 Deficiency Interrupts BATF3-Dependent Dendritic Cells Development
Sergei Grivennikov,
Fox Chase Cancer Center, USA
Tumor-Elicited Inflammation and Cytokines at Crossroads in Wound Healing and Tumor Progression
Tumor-Elicited Inflammation and Cytokines at Crossroads in Wound Healing and Tumor Progression
19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.
08:00—11:30
Parallels between Normal Tissue Repair Response and Oncogenesis
*
Carla V. Rothlin,
Yale University, USA
*
Neta Erez,
Tel Aviv University, Israel
Erik A. Sahai,
Francis Crick Institute, UK
Tumor-Stroma Cross-Talk in Metastasis and Therapy Failure
Tumor-Stroma Cross-Talk in Metastasis and Therapy Failure
Andreas Trumpp,
German Cancer Research Center, Germany
Stratification and Resistance Mechanisms in Pancreatic Cancer
Stratification and Resistance Mechanisms in Pancreatic Cancer
Annelise Snyder,
University of Washington, USA
Short Talk: Necroptotic Cell Death within the Tumor Microenvironment Promotes Tumor Control
Short Talk: Necroptotic Cell Death within the Tumor Microenvironment Promotes Tumor Control
Coffee Break
Alana L. Welm,
University of Utah School of Medicine, USA
Ron Kinase in Bone Remodeling and Bone Metastasis
Ron Kinase in Bone Remodeling and Bone Metastasis
Sheila A. Stewart,
Washington University School of Medicine, USA
Short Talk: Inhibition of Stromal p38MAPK Abrogates Breast Cancer Metastases
Short Talk: Inhibition of Stromal p38MAPK Abrogates Breast Cancer Metastases
Robert F. Schwabe,
Columbia University, USA
Fibrosis Promotes the Development of Liver Cancer
Fibrosis Promotes the Development of Liver Cancer
Mario A. Shields,
Cold Spring Harbor Laboratory, USA
Poster Teaser: Lysyl Oxidases Suppress Pancreatic Cancer Progression and Inhibit FAK and ERK Signaling
Poster Teaser: Lysyl Oxidases Suppress Pancreatic Cancer Progression and Inhibit FAK and ERK Signaling
Suzanne M. Ponik,
University of Wisconsin-Madison, USA
Poster Teaser: Collagen Matrix Density Drives the Metabolic Profile Shift of Breast Cancer Cells
Poster Teaser: Collagen Matrix Density Drives the Metabolic Profile Shift of Breast Cancer Cells
Daniel C. Rabe,
University of Chicago, USA
Poster Teaser: Exosome Crosstalk between Tumors and Tumor-Associated Macrophages Drives Pro-Invasive Plasticity
Poster Teaser: Exosome Crosstalk between Tumors and Tumor-Associated Macrophages Drives Pro-Invasive Plasticity
Julia Varga,
Georg Speyer Haus, Germany
Poster Teaser: Notch3 Activation in Response to Aberrant Akt Signaling Contributes to Colorectal Cancer Progression
Poster Teaser: Notch3 Activation in Response to Aberrant Akt Signaling Contributes to Colorectal Cancer Progression
14:30—16:30
Workshop 2: Therapy Resistance Mediated by Adaptive Responses in the Tumor Microenvironment
*
Weizhou Zhang,
University of Iowa, USA
Saran Kumar,
Hebrew University, Israel
Adjacency to Blood Vessels as a Generator of Tumor Cell Metabolic and Phenotypic Heterogeneities
Adjacency to Blood Vessels as a Generator of Tumor Cell Metabolic and Phenotypic Heterogeneities
Mihaela Skobe,
Icahn School of Medicine at Mount Sinai, USA
Lymphatic Endothelium Protects Breast Cancer Cells from Death by Inducing Metabolic Adaptations
Lymphatic Endothelium Protects Breast Cancer Cells from Death by Inducing Metabolic Adaptations
Melissa R. Junttila,
Genentech, Inc., USA
Identification of a Non-Genomic Resistance Mechanism to Vemurafenib in a BRAF Mutant Melanoma Model
Identification of a Non-Genomic Resistance Mechanism to Vemurafenib in a BRAF Mutant Melanoma Model
Peter Chockley,
University of Michigan Medical School, USA
EMT Confers Susceptibility to Metastasis-Specific Immune Surveillance in Lung Cancer
EMT Confers Susceptibility to Metastasis-Specific Immune Surveillance in Lung Cancer
Alexander Swarbrick,
Garvan Institute of Medical Research, Australia
The Paracrine Hedgehog-FGF Axis Mediates Cancer Stem Cell Plasticity in Triple Negative Breast Cancer
The Paracrine Hedgehog-FGF Axis Mediates Cancer Stem Cell Plasticity in Triple Negative Breast Cancer
*
Ela Elyada,
Cold Spring Harbor Laboratory, USA
Pancreatic Stellate Cell Dynamics in PDAC
Pancreatic Stellate Cell Dynamics in PDAC
Michael Timaner,
Technion-Israel Institute of Technology, Israel
Tumor-Associated Mesenchymal Stem Cells Preserve Cancer Stem Cells Niche in the Tumor Microenvironment Following Chemotherapy
Tumor-Associated Mesenchymal Stem Cells Preserve Cancer Stem Cells Niche in the Tumor Microenvironment Following Chemotherapy
17:00—19:00
Approaches to Visualize and Study Dynamics of the Tumor Microenvironment (“Imaging”)
*
Sergei Grivennikov,
Fox Chase Cancer Center, USA
*
Stefani Spranger,
Massachusetts Institute of Technology, USA
Mikala Egeblad,
Cold Spring Harbor Laboratory, USA
Imaging Reveals Tumor and Stromal Contributions to Formation of Metastases
Imaging Reveals Tumor and Stromal Contributions to Formation of Metastases
Danielle Seinstra,
Hubrecht Institute, Netherlands
Plasticity Between Epithelial and Mesenchymal States Unlinks EMT from Metastasis-Enhancing Stem Cell Capacity
Plasticity Between Epithelial and Mesenchymal States Unlinks EMT from Metastasis-Enhancing Stem Cell Capacity
Tracy W. Liu,
MD Anderson Cancer Center, USA
Short Talk: Imaging the Dynamics of Tumor NF-kB Transcriptional Activation and the Microenvironment In Vivo
Short Talk: Imaging the Dynamics of Tumor NF-kB Transcriptional Activation and the Microenvironment In Vivo
Matthew F. Krummel,
University of California, San Francisco, USA
Imaging and Deconvolving Tumor Antigen Flow in Primary and Metastatic Tumor Sites
Imaging and Deconvolving Tumor Antigen Flow in Primary and Metastatic Tumor Sites
19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.
08:00—11:15
Targeting the Changing Tumor Microenvironment for Anti-Cancer Therapies
*
Sheila A. Stewart,
Washington University School of Medicine, USA
*
Andrew J. Ewald,
Johns Hopkins University School of Medicine, USA
Karin E. de Visser,
Netherlands Cancer Institute, Netherlands
EMBO Young Investigator Lecture: Targeting Tumor-Induced Systemic Inflammation to Fight Metastatic Breast Cancer
EMBO Young Investigator Lecture: Targeting Tumor-Induced Systemic Inflammation to Fight Metastatic Breast Cancer
Carla V. Rothlin,
Yale University, USA
Innate Immune Checkpoints in Anti-Tumor Immunity
Innate Immune Checkpoints in Anti-Tumor Immunity
Deepak Nagrath,
University of Michigan, USA
Short Talk: Targeting Glutamine Synthetase in Tumors Disrupts Tumor Microenvironment-Regulated Cancer Cell Growth
Short Talk: Targeting Glutamine Synthetase in Tumors Disrupts Tumor Microenvironment-Regulated Cancer Cell Growth
Coffee Break
Sandra S. McAllister,
Brigham & Women's Hospital/Harvard Medical School, USA
Systemic Regulation of Tumor and Stromal Cell Plasticity
Systemic Regulation of Tumor and Stromal Cell Plasticity
Lionel J. Apetoh,
Centre Georges Francois Leclerc, France
Short Talk: Selective Degradation of the PU.1 Transcription Factor by Autophagy Represses TH9 Cell Differentiation
Short Talk: Selective Degradation of the PU.1 Transcription Factor by Autophagy Represses TH9 Cell Differentiation
Paula D. Bos,
Virginia Commonwealth University, USA
Short Talk: Treg-ulation of the Breast Tumor Microenvironment
Short Talk: Treg-ulation of the Breast Tumor Microenvironment
Weizhou Zhang,
University of Iowa, USA
Short Talk: Obesity-Related NLRC4 Inflammasome Activation and Angiogenesis in Breast Cancer
Short Talk: Obesity-Related NLRC4 Inflammasome Activation and Angiogenesis in Breast Cancer
17:00—18:15
Therapy Resistance Mediated by Adaptive Responses in the Tumor Microenvironment
*
Karin E. de Visser,
Netherlands Cancer Institute, Netherlands
*
Erik A. Sahai,
Francis Crick Institute, UK
Francois Ghiringhelli,
Centre de Recherche, INSERM U866, France
Chemotherapy and Reprogramming Immune and Cancer Cells
Chemotherapy and Reprogramming Immune and Cancer Cells
Stefani Spranger,
Massachusetts Institute of Technology, USA
Impact of Tumor Cell-Intrinsic Signaling on Anti-Tumor Immune Responses in the Tumor Microenvironment
Impact of Tumor Cell-Intrinsic Signaling on Anti-Tumor Immune Responses in the Tumor Microenvironment
18:15—19:00
Closing Keynote Address
*
Sergei Grivennikov,
Fox Chase Cancer Center, USA
*
Florian R. Greten,
Institute for Tumor Biology and Experimental Therapy, Germany
*
Mikala Egeblad,
Cold Spring Harbor Laboratory, USA
Robert A. Weinberg,
Massachusetts Institute of Technology, USA
The Epithelial-Mesenchymal Transition and Malignant Progression
The Epithelial-Mesenchymal Transition and Malignant Progression
19:15—20:15
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.
20:00—23:00
Entertainment
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.
*Session Chair †Invited, not yet responded.
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