Keystone Resort Floorplan
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This meeting took place in 2017
Here are the related meetings in 2021:
Obesity: From Cell to Patient - RESCHEDULING IN PROGRESS (J5)
Obesity: From Cell to Patient (EK17)
For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.
Obesity and Adipose Tissue Biology (J4)
Organizer(s) Marc L. Reitman, Ruth E. Gimeno and Jan Nedergaard
January 22—26, 2017
Keystone Resort • Keystone, CO USA
Discounted Abstract Deadline: Sep 22, 2016
Abstract Deadline: Oct 25, 2016
Scholarship Deadline: Sep 22, 2016
Discounted Registration Deadline: Nov 22, 2016
Sponsored by MedImmune, Nestlé Institute of Health Sciences and Novo Nordisk A/S. Part of the Keystone Symposia Global Health Series, supported by the Bill & Melinda Gates Foundation.
Joint Meeting:
Diabetes (J3)
Summary of Meeting:
Obesity is a growing worldwide epidemic, increasing co-morbid conditions, such as diabetes. The joint meetings on “Obesity and Adipose Tissue Biology” and “Diabetes: Emerging Concepts in Metabolic Signaling and Disease” are aimed to foster cross-talk between these research areas. Adipose tissue is an endocrine organ that is both controlled by and sends signals to the brain and other organs. In addition, obesity causes an inflammatory state in the adipose tissue. The recognition that brown/beige adipose tissue is active in adult humans has triggered interest in understanding the physiology and relative importance of these tissues. Exercise and bariatric surgery are known to elicit profound metabolic benefits in type 2 diabetes, although the underlying mechanisms remain unclear. This meeting will bring together cell biologists, biochemists, geneticists, physiologists, drug developers and clinical researchers, thereby facilitating knowledge exchange and interactions leading to elucidation of better treatments for obesity and diabetes. Specifically, it will examine recent advances in understanding of brown/beige adipose tissue function; obesity-induced adipose inflammation; control of adipose tissue, appetite, and energy metabolism; endocrine and paracrine signaling via secreted factors; molecular mechanisms of metabolic signaling; emerging topics, including long noncoding RNA and gut microbiome; and approaches to drug development and the treatment of obesity and diabetes.
View Scholarships/Awards
Obesity is a growing worldwide epidemic, increasing co-morbid conditions, such as diabetes. The joint meetings on “Obesity and Adipose Tissue Biology” and “Diabetes: Emerging Concepts in Metabolic Signaling and Disease” are aimed to foster cross-talk between these research areas. Adipose tissue is an endocrine organ that is both controlled by and sends signals to the brain and other organs. In addition, obesity causes an inflammatory state in the adipose tissue. The recognition that brown/beige adipose tissue is active in adult humans has triggered interest in understanding the physiology and relative importance of these tissues. Exercise and bariatric surgery are known to elicit profound metabolic benefits in type 2 diabetes, although the underlying mechanisms remain unclear. This meeting will bring together cell biologists, biochemists, geneticists, physiologists, drug developers and clinical researchers, thereby facilitating knowledge exchange and interactions leading to elucidation of better treatments for obesity and diabetes. Specifically, it will examine recent advances in understanding of brown/beige adipose tissue function; obesity-induced adipose inflammation; control of adipose tissue, appetite, and energy metabolism; endocrine and paracrine signaling via secreted factors; molecular mechanisms of metabolic signaling; emerging topics, including long noncoding RNA and gut microbiome; and approaches to drug development and the treatment of obesity and diabetes.
View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference
The meeting will begin on Sunday, January 22 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, January 26 with a closing plenary session from 17:00 to 19:30, followed by a social hour and entertainment. We recommend return travel on Friday, January 27 in order to fully experience the meeting.
SUNDAY, JANUARY 22
MONDAY, JANUARY 23
TUESDAY, JANUARY 24
WEDNESDAY, JANUARY 25
THURSDAY, JANUARY 26
FRIDAY, JANUARY 27
Conference Program Print | View meeting in 12 hr (am/pm) time
The meeting will begin on Sunday, January 22 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, January 26 with a closing plenary session from 17:00 to 19:30, followed by a social hour and entertainment. We recommend return travel on Friday, January 27 in order to fully experience the meeting.
SUNDAY, JANUARY 22
18:00—20:00
Welcome Mixer
No registration fees are used to fund alcohol served at this function.
08:00—09:30
Welcome and Keynote Session (Joint)
*
Jiandie Lin,
University of Michigan Medical School, USA
*
Marc L. Reitman,
NIDDK, National Institutes of Health, USA
Philipp E. Scherer,
University of Texas Southwestern Medical Center, USA
Journal of Lipid Research Lectureship: Adipose Origin and Expansion
Journal of Lipid Research Lectureship: Adipose Origin and Expansion
Richard D. DiMarchi,
Indiana University and Novo Nordisk, USA
Chemical Biotechnology Applied to Metabolic Diseases
Chemical Biotechnology Applied to Metabolic Diseases
Coffee Break
09:50—12:15
Brown/Beige Fat Activation and Function (Joint)
*
Antonio J. Vidal-Puig,
University of Cambridge, UK
Jan Nedergaard,
Stockholm University, Sweden
Brown Adipose Physiology
Brown Adipose Physiology
Aaron M. Cypess,
NIDDK, National Institutes of Health, USA
Activation of Brown Adipose Tissue in Humans
Activation of Brown Adipose Tissue in Humans
Ajay Chawla,
Merck and University of California, San Francisco, USA
Innate Immune Licensing of Thermogenesis
Innate Immune Licensing of Thermogenesis
Patrick Seale,
University of Pennsylvania, USA
Regulators of Brown and Beige Fat Activity
Regulators of Brown and Beige Fat Activity
14:30—16:30
Workshop 1: Drug Discovery/Development in Obesity (Joint)
Bei Shan,
Lilly China Research and Development Center, China
Michelle L. Boland,
Medimmune, USA
MEDI0382, a Dual GLP-1/Glucagon Receptor Agonist, is More Effective on Alleviating Non-Alcoholic Steatohepatitis (NASH) Compared to Liraglutide in a Mouse Model of NASH
MEDI0382, a Dual GLP-1/Glucagon Receptor Agonist, is More Effective on Alleviating Non-Alcoholic Steatohepatitis (NASH) Compared to Liraglutide in a Mouse Model of NASH
Andrea Galmozzi,
The Scripps Research Institute, USA
Chemoproteomics-driven Discovery of PGRMC2 as a New Regulator of Adipocyte Physiology with Therapeutic Potential in Obesity-Linked Diabetes
Chemoproteomics-driven Discovery of PGRMC2 as a New Regulator of Adipocyte Physiology with Therapeutic Potential in Obesity-Linked Diabetes
Hua V. Lin,
Forkhead BioTherapeutics Inc, USA
GPR142 Agonists Improve Beta Cell Proliferation and Survival
GPR142 Agonists Improve Beta Cell Proliferation and Survival
Kfir Sharabi,
Dana-Farber Cancer Institute, USA
Small Molecule Screen Identifies Selective PGC-1alpha Gluconeogenic Inhibitors that Ameliorate Diabetic Symptoms
Small Molecule Screen Identifies Selective PGC-1alpha Gluconeogenic Inhibitors that Ameliorate Diabetic Symptoms
Cholsoon Jang,
Princeton University, USA
A Metabolite of Branched Chain Amino Acids Drives Vascular Fatty Acid Transport and Insulin Resistance
A Metabolite of Branched Chain Amino Acids Drives Vascular Fatty Acid Transport and Insulin Resistance
Zheng Sun,
Baylor College of Medicine, USA
Dissociation of Muscle Glucose Utilization from Exercise Endurance by Circadian Epigenomic Regulator HDAC3
Dissociation of Muscle Glucose Utilization from Exercise Endurance by Circadian Epigenomic Regulator HDAC3
Jonathan Z. Long,
Dana-Farber Cancer Institute, USA
The Secreted Enzyme PM20D1 Regulates Lipidated Amino Acid Uncouplers of Mitochondria
The Secreted Enzyme PM20D1 Regulates Lipidated Amino Acid Uncouplers of Mitochondria
Nicolai Jacob Wewer Albrechtsen,
University of Copenhagen, Denmark
An Insulinotropic Glucagon Variant Identified in Man
An Insulinotropic Glucagon Variant Identified in Man
17:00—19:15
Adipose Tissue Development
*
Mitchell A. Lazar,
Perelman School of Medicine, University of Pennsylvania, USA
Evan D. Rosen,
Harvard University, USA
Insights from the Epigenomic Analysis of Human and Murine Adipose Tissue
Insights from the Epigenomic Analysis of Human and Murine Adipose Tissue
Silvia Corvera,
University of Massachusetts Medical School, USA
Origin and Function of Human Brite/Beige Adipocytes
Origin and Function of Human Brite/Beige Adipocytes
Zachary Sebo,
Yale University, USA
Short Talk: A Sexually Dimorphic Mesodermal Fate Map for Adipose Tissue
Short Talk: A Sexually Dimorphic Mesodermal Fate Map for Adipose Tissue
Rana K. Gupta,
University of Texas Southwestern Medical Center, USA
Short Talk: Visceral Adipocyte Differentiation from Mural Adipose Precursors Protects Against Pathological Adipose Tissue Expansion and Insulin Resistance in Obesity
Short Talk: Visceral Adipocyte Differentiation from Mural Adipose Precursors Protects Against Pathological Adipose Tissue Expansion and Insulin Resistance in Obesity
17:00—19:00
Exercise and Type 2 Diabetes
*
Clay F. Semenkovich,
Washington University School of Medicine, USA
Laurie J. Goodyear,
Joslin Diabetes Center, Harvard Medical School, USA
Exercise Regulation of Adipose Tissue
Exercise Regulation of Adipose Tissue
Juleen R. Zierath,
Karolinska Institutet, Sweden
The Role of Diet and Exercise in the Epigenetic Landscape of Type 2 Diabetes
The Role of Diet and Exercise in the Epigenetic Landscape of Type 2 Diabetes
Christoph Handschin,
University of Basel, Switzerland
Regulation of Physiological and Dietary Ketone Body Homeostasis and Diabetic Hyperketosis by Muscle PGC-1alpha and Exercise
Regulation of Physiological and Dietary Ketone Body Homeostasis and Diabetic Hyperketosis by Muscle PGC-1alpha and Exercise
Xingxing Kong,
Beth Israel Deaconess Medical Center, Harvard Medical School, USA
Short Talk: Brown Fat Dysfunction Induces Skeletal Muscle Myopathy via an IRF4-Myostatin-Mediated Pathway
Short Talk: Brown Fat Dysfunction Induces Skeletal Muscle Myopathy via an IRF4-Myostatin-Mediated Pathway
19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.
08:00—11:15
Interorgan Metabolic Crosstalk via Secreted Factors (Joint)
*
Christoph Handschin,
University of Basel, Switzerland
Takashi Kadowaki,
University of Tokyo, Japan
Adiponectin Receptors: A Major Treatment Target in Type 2 Diabetes and Obesity-Linked Diseases
Adiponectin Receptors: A Major Treatment Target in Type 2 Diabetes and Obesity-Linked Diseases
Jiandie Lin,
University of Michigan Medical School, USA
The Brown Fat Secretome: Metabolic Functions Beyond Thermogenesis
The Brown Fat Secretome: Metabolic Functions Beyond Thermogenesis
Coffee Break
David J. Mangelsdorf,
University of Texas Southwestern Medical Center, USA
The Diverse Metabolic Actions of FGF21
The Diverse Metabolic Actions of FGF21
Yonghao Yu,
University of Texas Southwestern Medical Center, USA
Large Scale Proteomic Analysis Identifies IGFBP5 as a Secreted mTORC1 Target that Mediates mTORC1-Dependent Feedback Inhibition of IGF-1 Signaling
Large Scale Proteomic Analysis Identifies IGFBP5 as a Secreted mTORC1 Target that Mediates mTORC1-Dependent Feedback Inhibition of IGF-1 Signaling
Russell A. Miller,
Pfizer Inc., USA
Short Talk: Glucagon Stimulates Hepatic Glutamine Utilization by Increasing Metabolic Flux through GLS2
Short Talk: Glucagon Stimulates Hepatic Glutamine Utilization by Increasing Metabolic Flux through GLS2
Lucas BonDurant,
Alnylam Pharmaceuticals, USA
Short Talk: FGF21 Signals Directly to Adipose Tissues to Acutely Enhance Insulin Sensitivity
Short Talk: FGF21 Signals Directly to Adipose Tissues to Acutely Enhance Insulin Sensitivity
17:00—19:15
Adipose Inflammation; Adipokines
*
Ajay Chawla,
Merck and University of California, San Francisco, USA
Ruth E. Gimeno,
Eli Lilly and Company, USA
Pharmacological Approaches to Adipose Tissue Function
Pharmacological Approaches to Adipose Tissue Function
Anthony W. Ferrante,
Columbia University, USA
Induction of Adipose Tissue Inflammation
Induction of Adipose Tissue Inflammation
Prashant Rajbhandari,
Icahn School of Medicine at Mount Sinai, USA
Short Talk: Interleukin-10 Signaling Alters Chromatin Architecture in Adipose to Regulate Thermogenesis and Energy Expenditure
Short Talk: Interleukin-10 Signaling Alters Chromatin Architecture in Adipose to Regulate Thermogenesis and Energy Expenditure
Min Jeong Choi,
Chungnam National University, South Korea
Short Talk: Secretory Factors Induced by Adipocyte Mitochondrial OxPhos Dysfunction Modulate Systemic Metabolism by Influencing the Adipose Immune Environment
Short Talk: Secretory Factors Induced by Adipocyte Mitochondrial OxPhos Dysfunction Modulate Systemic Metabolism by Influencing the Adipose Immune Environment
17:00—19:00
Long Noncoding and MicroRNAs and Metabolism
*
Jiandie Lin,
University of Michigan Medical School, USA
Lori Sussel,
University of Colorado Anschutz Medical Campus, USA
Non-Coding Gene Regulation of the Pancreatic Islet
Non-Coding Gene Regulation of the Pancreatic Islet
Lei Sun,
Duke-NUS Graduate Medical School Singapore, Singapore
Regulatory Role of Long Noncoding RNAs in Adipose
Regulatory Role of Long Noncoding RNAs in Adipose
Rohit N. Kulkarni,
Joslin Diabetes Center, Harvard Medical School, USA
A Role for MicroRNAs in Diabetes and Its Complications
A Role for MicroRNAs in Diabetes and Its Complications
Congcong He,
Northwestern University, USA
Short Talk: Differential Roles of Autophagy in Insulin Production and Sensitivity
Short Talk: Differential Roles of Autophagy in Insulin Production and Sensitivity
19:15—20:15
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.
08:00—11:15
Gut Microbiome and Bariatric Surgery (Joint)
Patrice D. Cani,
Université Catholique de Louvain, Belgium
Specific Gut Microbiota and Intestinal Sensors: Focus on Novel Mechanisms Affecting Glucose and Energy Metabolism
Specific Gut Microbiota and Intestinal Sensors: Focus on Novel Mechanisms Affecting Glucose and Energy Metabolism
*
Randy J. Seeley,
University of Michigan, USA
Gut Endocrine Signaling in Bariatric Surgery
Gut Endocrine Signaling in Bariatric Surgery
Coffee Break
Helen Raybould,
University of California, Davis, USA
The Microbiota-Gut-Brain Axis in the Control of Food Intake and Body Weight
The Microbiota-Gut-Brain Axis in the Control of Food Intake and Body Weight
Fredrik Bäckhed,
University of Gothenburg, Sweden
Does Altered Gut Microbiome after Bariatric Surgery Contribute to Improved Metabolism?
Does Altered Gut Microbiome after Bariatric Surgery Contribute to Improved Metabolism?
Jantje M. Gerdes,
Helmholtz Zentrum München, Germany
Short Talk: EphA/ephrin Signaling in Pancreatic Islets is Regulated by Primary Cilia
Short Talk: EphA/ephrin Signaling in Pancreatic Islets is Regulated by Primary Cilia
Chieh Jason Chou,
Nestlé Institute of Health Sciences SA, Switzerland
Short Talk: The Effect of Diets on the Metabolic Benefits Associated with Post Bariatric Surgery Microbiota
Short Talk: The Effect of Diets on the Metabolic Benefits Associated with Post Bariatric Surgery Microbiota
17:00—19:15
Neural Control of Adipose/Adipose Function
*
Jan Nedergaard,
Stockholm University, Sweden
Heike Münzberg,
Pennington Biomedical Research Center, USA
Central Circuits of Thermoregulatory Leptin Action
Central Circuits of Thermoregulatory Leptin Action
Rudolf Zechner,
University of Graz, Austria
Adipose Triglyceride Lipase
Adipose Triglyceride Lipase
Joerg Heeren,
University Medical Center Hamburg-Eppendorf, Germany
Brown Fat and Lipid Metabolism
Brown Fat and Lipid Metabolism
Peter K. Jackson,
Stanford University, USA
Short Talk: Linking Monogenic and Complex Obesity to Primary Cilia: The Cep19 Obesity Protein Regulates a Conserved GTPase Cycle Coupling Cargo to the IFT-B Complex for Ciliary Transport of the BBSome and GPCRs
Short Talk: Linking Monogenic and Complex Obesity to Primary Cilia: The Cep19 Obesity Protein Regulates a Conserved GTPase Cycle Coupling Cargo to the IFT-B Complex for Ciliary Transport of the BBSome and GPCRs
Qi Wu,
Baylor College of Medicine, USA
Short Talk: Deciphering an AgRP-Dorsal Raphe Neural Circuit in Exclusive Control of Energy Expenditure
Short Talk: Deciphering an AgRP-Dorsal Raphe Neural Circuit in Exclusive Control of Energy Expenditure
17:00—19:00
Substrate Flux and Metabolic Signaling
*
Philipp E. Scherer,
University of Texas Southwestern Medical Center, USA
Clay F. Semenkovich,
Washington University School of Medicine, USA
Lipid-Mediated Metabolic Signaling
Lipid-Mediated Metabolic Signaling
Gerald I. Shulman,
Yale University School of Medicine, USA
Role of Hepatic Acetyl CoA in the Regulation of Hepatic Gluconeogenesis in Normal and Diabetic States
Role of Hepatic Acetyl CoA in the Regulation of Hepatic Gluconeogenesis in Normal and Diabetic States
Christopher B. Newgard,
Duke University Medical Center, USA
Metabolic Flux and Homeostais
Metabolic Flux and Homeostais
Hongyuan Yang,
University of New South Wales, Australia
Short Talk: Understanding Congenital Generalized Lipodystrophy
Short Talk: Understanding Congenital Generalized Lipodystrophy
19:15—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.
08:00—11:00
Genetics and Systems Biology
*
Evan D. Rosen,
Harvard University, USA
Umut Ozcan,
Harvard Medical School, USA
Role of Endoplasmic Reticulum Stress in Development of Obesity and Type 2 Diabetes
Role of Endoplasmic Reticulum Stress in Development of Obesity and Type 2 Diabetes
Ruth J.F. Loos,
Mount Sinai School of Medicine, USA
The Genetics of Obesity - Going Beyond Common Variation and Common Phenotypes
The Genetics of Obesity - Going Beyond Common Variation and Common Phenotypes
Coffee Break
Mitchell A. Lazar,
Perelman School of Medicine, University of Pennsylvania, USA
Transcriptional Regulation of Metabolism
Transcriptional Regulation of Metabolism
Yi Chen,
Dana-Farber Cancer Institute, USA
Short Talk: Potassium Current Through KCNK3 Regulates Brown Adipose Thermogenesis and Obesity
Short Talk: Potassium Current Through KCNK3 Regulates Brown Adipose Thermogenesis and Obesity
08:00—11:15
Mechanisms of Nutrient Signaling
*
Laurie J. Goodyear,
Joslin Diabetes Center, Harvard Medical School, USA
Antonio J. Vidal-Puig,
University of Cambridge, UK
Adipose Tissue Expandability, Lipotoxicity and the Metabolic Syndrome
Adipose Tissue Expandability, Lipotoxicity and the Metabolic Syndrome
C. Ronald Kahn,
Joslin Diabetes Center and Harvard Medical School, USA
Metabolic Signaling in Physiology and Disease
Metabolic Signaling in Physiology and Disease
Coffee Break
Hei Sook Sul,
University of California, Berkeley, USA
Regulation of Fat Metabolism
Regulation of Fat Metabolism
Jun Wu,
University of Michigan, USA
Beige-Fat-Specific Regulation in Mouse and Human
Beige-Fat-Specific Regulation in Mouse and Human
Feng Liu,
University of Texas Health Science Center, USA
Short Talk: DsbA-L Suppresses Inflammation and Promotes Beiging and Thermogenesis by Improving Mitochondrial Function
Short Talk: DsbA-L Suppresses Inflammation and Promotes Beiging and Thermogenesis by Improving Mitochondrial Function
Adilson L. Guilherme,
University of Massachusetts Medical School, USA
Short Talk: Suppression of Adipocyte Fatty Acid Synthase in Adult Mice Enhances Adipose Sympathetic Activity and Browning to Improve Glucose Homeostasis in Obese Mice
Short Talk: Suppression of Adipocyte Fatty Acid Synthase in Adult Mice Enhances Adipose Sympathetic Activity and Browning to Improve Glucose Homeostasis in Obese Mice
14:30—16:30
Workshop 2: Adipose Thermogenesis and a Little Bit More
*
Barbara Cannon,
Stockholm University, Sweden
*
Matthias Blüher,
University of Leipzig, Germany
Erin L. Brown,
Johns Hopkins Medical Institute, USA
Regulation of Adipose Tissue Thermogenic Capacity by Estrogen-Related Receptors
Regulation of Adipose Tissue Thermogenic Capacity by Estrogen-Related Receptors
Shunbun Kita,
Graduate School of Medicine, Osaka University, Japan
Adiponectin/T-Cadherin System Regulates Exosome Biogenesis and Systemic Plasma Exosome Level
Adiponectin/T-Cadherin System Regulates Exosome Biogenesis and Systemic Plasma Exosome Level
Pegah Poursharifi,
University of Montreal-CRCHUM, Canada
ABHD6 Negatively Regulates Thermogenic Adaptive Responses under Cold Stress
ABHD6 Negatively Regulates Thermogenic Adaptive Responses under Cold Stress
Pingwen Xu,
Baylor College of Medicine, USA
Ventral Medial Hypothalamus ERalpha Neurocircuits in the Regulation of Thermogenesis and Physical Activity
Ventral Medial Hypothalamus ERalpha Neurocircuits in the Regulation of Thermogenesis and Physical Activity
Ludger Scheja,
University Medical Center Hamburg-Eppendorf, Germany
Carbohydrate Response Element Binding Protein Regulates de novo Lipogenesis in Brown Adipose Tissue and Adaptive thermogenesis
Carbohydrate Response Element Binding Protein Regulates de novo Lipogenesis in Brown Adipose Tissue and Adaptive thermogenesis
Roland H. Stimson,
University of Edinburgh, Scotland
Direct Measurement of in vivo Substrate Utilisation by Human Brown Adipose Tissue
Direct Measurement of in vivo Substrate Utilisation by Human Brown Adipose Tissue
Claudio J. Villanueva,
University of California, Los Angeles, USA
Global Analysis of Plasma Lipids Identifies Liver-Derived Acyl-Carnitines as a Fuel Source for Brown Fat Thermogenesis
Global Analysis of Plasma Lipids Identifies Liver-Derived Acyl-Carnitines as a Fuel Source for Brown Fat Thermogenesis
Mary N. Teruel,
Stanford University, USA
Transcription Factor Dynamics Define a Circadian Code for Fat Cell Differentiation
Transcription Factor Dynamics Define a Circadian Code for Fat Cell Differentiation
14:30—16:30
Workshop 2: Metabolic Regulation in Physiology and Disease
*
Dave Bridges,
University of Michigan, USA
Constanza J. Cortes Rodriguez,
University of Alabama at Birmingham, USA
Skeletal Muscle Control of Systemic Metabolism: A Role for Transcription Factor E-B (TFEB) Signaling
Skeletal Muscle Control of Systemic Metabolism: A Role for Transcription Factor E-B (TFEB) Signaling
Zhuoxian Meng,
University of Michigan, USA
Glucose Sensing by Skeletal Myocytes Couples Nutrient Signaling to Systemic Homeostasis
Glucose Sensing by Skeletal Myocytes Couples Nutrient Signaling to Systemic Homeostasis
Tiemin Liu,
University of Texas Southwestern Medical Center, USA
5-HT2C Receptors in Brainstem Neurons Regulate Glucose Homeostasis
5-HT2C Receptors in Brainstem Neurons Regulate Glucose Homeostasis
Fajun Yang,
Albert Einstein College of Medicine, USA
Cyclin C Regulates Brown Fat Development and Function
Cyclin C Regulates Brown Fat Development and Function
Yanhui Zhang,
University of Iowa, USA
SWELL1 is a Regulator of Adipocyte Size, Insulin Signaling and Glucose Homeostasis
SWELL1 is a Regulator of Adipocyte Size, Insulin Signaling and Glucose Homeostasis
Andrew C. Shin,
Texas Tech University, USA
Insulin Receptor Signaling in POMC, but not AgRP, Neurons Controls Adipose Tissue Insulin Action
Insulin Receptor Signaling in POMC, but not AgRP, Neurons Controls Adipose Tissue Insulin Action
Jakob G. Knudsen,
University of Oxford, UK
Glucagon Secretion is Dependent on Alpha-Cell Fatty Acid Oxidation
Glucagon Secretion is Dependent on Alpha-Cell Fatty Acid Oxidation
Meilian Liu,
University of New Mexico Health Sciences Center, USA
Adipose mTORC1 Suppresses Beige Fat Development via Autophagy-Dependent Mechanisms
Adipose mTORC1 Suppresses Beige Fat Development via Autophagy-Dependent Mechanisms
17:00—19:15
Treatment of Obesity
*
Ruth E. Gimeno,
Eli Lilly and Company, USA
Matthias Blüher,
University of Leipzig, Germany
New Developments in Treatment of Obesity
New Developments in Treatment of Obesity
Marc L. Reitman,
NIDDK, National Institutes of Health, USA
Role of Body and Environmental Temperature in Energy Homeostasis and Drug Development
Role of Body and Environmental Temperature in Energy Homeostasis and Drug Development
Denis P. Blondin,
University of Sherbrooke, Canada
Short Talk: The Use of a Beta3-Adrenergic Receptor Agonist in Humans Stimulates BAT Glucose Disposal, but not Thermogenesis
Short Talk: The Use of a Beta3-Adrenergic Receptor Agonist in Humans Stimulates BAT Glucose Disposal, but not Thermogenesis
Minna Lahesmaa,
Turku PET Centre, Finland
Short Talk: Cannabinoid CB1 Receptors in Human Brown Adipose Tissue during Cold Exposure
Short Talk: Cannabinoid CB1 Receptors in Human Brown Adipose Tissue during Cold Exposure
17:00—18:45
Emerging Topics in Diabetes
*
Rohit N. Kulkarni,
Joslin Diabetes Center, Harvard Medical School, USA
Ralph A. DeFronzo,
University of Texas Health Sciences Center at San Antonio, USA
The Kidney and Glucose Homeostasis: Implications for Therapy
The Kidney and Glucose Homeostasis: Implications for Therapy
Jayne S. Danska,
Hospital for Sick Children Research Institute, Canada
Diabetes Trialog: Genes, Sex and the Microbiome
Diabetes Trialog: Genes, Sex and the Microbiome
18:45—19:00
Meeting Wrap-Up: Outcomes and Future Directions
*
Clay F. Semenkovich,
Washington University School of Medicine, USA
19:30—20:30
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.
20:00—23:00
Entertainment
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources. Novo Nordisk A/S funding is not being used for this function.
*Session Chair †Invited, not yet responded.
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