Fairmont Banff Springs Floorplan

Registered Attendees
Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:
- Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting
(You can edit your own abstract from My Account page as well)
NOTE: Abstract authors/submitters may choose to not have their abstract available online and in the secure mobile app until a week before the meeting.
- Full participant list, including joint meeting participants
- Printable Invoices and Invitation Letters
- Scholarship Information
- Lodging Information
Login to My Account page
This meeting took place in 2017
Here are the related meetings in 2021:
Non-Coding RNAs: Biology and Applications (EK44)
For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.
Noncoding RNAs: From Disease to Targeted Therapeutics (J5)
Organizer(s) Kevin V. Morris, Archa Fox and Paloma Hoban Giangrande
February 5—9, 2017
Fairmont Banff Springs • Banff, AB Canada
Discounted Abstract Deadline: Oct 5, 2016
Abstract Deadline: Nov 2, 2016
Scholarship Deadline: Oct 5, 2016
Discounted Registration Deadline: Dec 6, 2016
Sponsored by Cell Research, Ionis Pharmaceuticals, Inc. Merck & Co., Inc. and Moderna Therapeutics
Joint Meeting:
Protein-RNA Interactions: Scale, Mechanisms, Structure and Function of Coding and Noncoding RNPs (J6)
Summary of Meeting:
It has become apparent over the last decade that small and long noncoding RNAs play a major role in the regulation of gene expression and disease. While much emphasis has been centered on the role of noncoding RNAs in human disease, a gap remains in utilizing this knowledge to develop target specific approaches to disrupting noncoding RNA pathways for therapeutic gain. This meeting will for the first time bring together an interdisciplinary group of basic and applied noncoding RNA scientists in an effort to translate our current understanding of noncoding RNA biology into meaningful therapeutics for many of those diseases afflicting society. To accomplish this goal, the meeting will aim to: (1) Introduce the broad genome-wide basic fabric of noncoding RNA regulation and form and function in the cell; (2) Focus on direct RNA/chromatin/DNA or RNA/protein interactions with candidate disease-relevant model systems; and (3) Highlight synthetic biological approaches to developing RNA or oligonucleotide mimics to target and/or disrupt particular disease-relevant noncoding RNA pathways. The goal of this meeting is to bring together basic and applied scientists working on noncoding RNAs in an effort to not only better understand the role noncoding RNAs play in the regulation of disease-relevant genes but also the emerging ability to utilize this knowledge to develop targeted therapeutics, an eventuality that heralds a new frontier in drug development and therapeutics.
View Scholarships/Awards
It has become apparent over the last decade that small and long noncoding RNAs play a major role in the regulation of gene expression and disease. While much emphasis has been centered on the role of noncoding RNAs in human disease, a gap remains in utilizing this knowledge to develop target specific approaches to disrupting noncoding RNA pathways for therapeutic gain. This meeting will for the first time bring together an interdisciplinary group of basic and applied noncoding RNA scientists in an effort to translate our current understanding of noncoding RNA biology into meaningful therapeutics for many of those diseases afflicting society. To accomplish this goal, the meeting will aim to: (1) Introduce the broad genome-wide basic fabric of noncoding RNA regulation and form and function in the cell; (2) Focus on direct RNA/chromatin/DNA or RNA/protein interactions with candidate disease-relevant model systems; and (3) Highlight synthetic biological approaches to developing RNA or oligonucleotide mimics to target and/or disrupt particular disease-relevant noncoding RNA pathways. The goal of this meeting is to bring together basic and applied scientists working on noncoding RNAs in an effort to not only better understand the role noncoding RNAs play in the regulation of disease-relevant genes but also the emerging ability to utilize this knowledge to develop targeted therapeutics, an eventuality that heralds a new frontier in drug development and therapeutics.
View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference
The meeting will begin on Sunday, February 5 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, February 9 with a closing plenary session from 17:00 to 19:15, followed by a social hour and entertainment. We recommend return travel on Friday, February 10 in order to fully experience the meeting.
SUNDAY, FEBRUARY 5
MONDAY, FEBRUARY 6
Following Session is for Protein-RNA Interactions: Scale, Mechanisms, Structure and Function of Coding and Noncoding RNPs (J6)
TUESDAY, FEBRUARY 7
Following Session is for Protein-RNA Interactions: Scale, Mechanisms, Structure and Function of Coding and Noncoding RNPs (J6)
Following Session is for Protein-RNA Interactions: Scale, Mechanisms, Structure and Function of Coding and Noncoding RNPs (J6)
Following Session is for Protein-RNA Interactions: Scale, Mechanisms, Structure and Function of Coding and Noncoding RNPs (J6)
WEDNESDAY, FEBRUARY 8
Following Session is for Protein-RNA Interactions: Scale, Mechanisms, Structure and Function of Coding and Noncoding RNPs (J6)
Following Session is for Protein-RNA Interactions: Scale, Mechanisms, Structure and Function of Coding and Noncoding RNPs (J6)
Following Session is for Protein-RNA Interactions: Scale, Mechanisms, Structure and Function of Coding and Noncoding RNPs (J6)
THURSDAY, FEBRUARY 9
Following Session is for Protein-RNA Interactions: Scale, Mechanisms, Structure and Function of Coding and Noncoding RNPs (J6)
Following Session is for Protein-RNA Interactions: Scale, Mechanisms, Structure and Function of Coding and Noncoding RNPs (J6)
FRIDAY, FEBRUARY 10
Conference Program Print | View meeting in 12 hr (am/pm) time
The meeting will begin on Sunday, February 5 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, February 9 with a closing plenary session from 17:00 to 19:15, followed by a social hour and entertainment. We recommend return travel on Friday, February 10 in order to fully experience the meeting.
SUNDAY, FEBRUARY 5
18:00—20:00
Welcome Mixer
No registration fees are used to fund alcohol served at this function.
08:00—09:30
Welcome and Keynote Session (Joint)
*
Kevin V. Morris,
Center for Gene Therapy, City of Hope, USA
*
Gene W. Yeo,
University of California, San Diego, USA
Thomas R. Cech,
HHMI/University of Colorado, USA
Noncoding RNA-Protein Interactions: Telomerase and PRC2
Noncoding RNA-Protein Interactions: Telomerase and PRC2
Gerald F. Joyce,
The Salk Institute, USA
Tertiary Structured RNAs as Potential Therapeutic Targets
Tertiary Structured RNAs as Potential Therapeutic Targets
Coffee Break
09:50—11:15
Noncoding RNAs and RNA-Protein Interactions (Joint)
*
Saba Valadkhan,
Case Western Reserve University, USA
Gene W. Yeo,
University of California, San Diego, USA
Large-Scale Assessment of the Functions and Targets of Hundreds of RNA Binding Proteins
Large-Scale Assessment of the Functions and Targets of Hundreds of RNA Binding Proteins
Archa Fox,
University of Western Australia, Australia
New Insights into NEAT1 Long Noncoding RNA and Paraspeckles
New Insights into NEAT1 Long Noncoding RNA and Paraspeckles
Sarah D. Diermeier,
University of Otago, New Zealand
Short Talk: Mammary Tumor Associated RNAs (MaTARs) as Drivers of Tumor Cell Growth and Metastasis
Short Talk: Mammary Tumor Associated RNAs (MaTARs) as Drivers of Tumor Cell Growth and Metastasis
17:00—19:00
Disease-Specific Noncoding RNAs: From Complex Genomic Interactions to Mechanism
*
John L. Rinn,
University of Colorado Boulder, USA
Musa M. Mhlanga,
Radboud Institute for Molecular Life Sciences, Netherlands
Higher Order Genome Architecture and LncRNAs Permit Robust Transcription of Immune Genes
Higher Order Genome Architecture and LncRNAs Permit Robust Transcription of Immune Genes
Jane E. Freedman,
University of Massachusetts Medical School, USA
Expression of Noncoding RNAs in Human Populations and Disease
Expression of Noncoding RNAs in Human Populations and Disease
Eleonora Leucci,
KU Leuven, Belgium
Short Talk: SAMMSON Coordinates Cell and Mitochondrial Ribosome Biogenesis to Promote Tumor Progression
Short Talk: SAMMSON Coordinates Cell and Mitochondrial Ribosome Biogenesis to Promote Tumor Progression
Following Session is for Protein-RNA Interactions: Scale, Mechanisms, Structure and Function of Coding and Noncoding RNPs (J6)
17:00—19:00
Complete Characterization of RNP Proteomes: Coding and Noncoding RNAs
*
Jernej Ule,
Francis Crick Institute & UCL, UK
Matthias W. Hentze,
European Molecular Biology Laboratory, Germany
Smartphone Proteins Connecting Gene Expression and Metabolism
Smartphone Proteins Connecting Gene Expression and Metabolism
Marlene Oeffinger,
Institut de Recherches Cliniques de Montreal, Canada
Correlative Proteome-RNome Analysis to Investigate Variant Interactomes along Gene Expression Pathways
Correlative Proteome-RNome Analysis to Investigate Variant Interactomes along Gene Expression Pathways
Karla M. Neugebauer,
Yale University, USA
Dynamic RNA-Protein Interactions and Nuclear Organization Support Zebrafish Embryogenesis
Dynamic RNA-Protein Interactions and Nuclear Organization Support Zebrafish Embryogenesis
Eric L. Van Nostrand,
University of California, San Diego, USA
Short Talk: The Landscape of Protein-RNA Interactions: Insights from eCLIP of 126 RNA Binding Proteins
Short Talk: The Landscape of Protein-RNA Interactions: Insights from eCLIP of 126 RNA Binding Proteins
19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.
08:00—11:15
Molecular Mechanisms and Functional Studies of Protein Interactions with Noncoding RNAs in Disease
*
Kevin V. Morris,
Center for Gene Therapy, City of Hope, USA
John L. Rinn,
University of Colorado Boulder, USA
Chromatin Environment, Transcriptional Regulation, and Splicing Distinguish lincRNAs and mRNAs
Chromatin Environment, Transcriptional Regulation, and Splicing Distinguish lincRNAs and mRNAs
Ingrid Grummt,
German Cancer Research Center, Germany
DNA:RNA Triple Helices: A Liaison between Noncoding RNAs and Chromatin
DNA:RNA Triple Helices: A Liaison between Noncoding RNAs and Chromatin
Coffee Break
Charlie Bond,
University of Western Australia, Australia
High-Resolution Structural Studies and Gel- and Filament-Forming Properties of Paraspeckle RNA-Binding Proteins
High-Resolution Structural Studies and Gel- and Filament-Forming Properties of Paraspeckle RNA-Binding Proteins
Kaveh Daneshvar,
Harvard Medical School, USA
Short Talk: RNA-Aptamer Chimera Crosslinking and Pull-Down to Identify Proteins that Interact with the Long Noncoding RNA DIGIT
Short Talk: RNA-Aptamer Chimera Crosslinking and Pull-Down to Identify Proteins that Interact with the Long Noncoding RNA DIGIT
Meredith Corley,
University of North Carolina at Chapel Hill, USA
Short Talk: An RNA Structure Mediated, Post-Transcriptional Model of alpha-1-antitrypsin Expression
Short Talk: An RNA Structure Mediated, Post-Transcriptional Model of alpha-1-antitrypsin Expression
Following Session is for Protein-RNA Interactions: Scale, Mechanisms, Structure and Function of Coding and Noncoding RNPs (J6)
08:00—11:00
Protein-RNA Localization
*
Gene W. Yeo,
University of California, San Diego, USA
Eric Lecuyer,
Institut de Recherches Cliniques de Montreal, Canada Joint Institute, Canada
Systematic Characterization of the Subcellular Distribution Properties of Human RNA Binding Proteins
Systematic Characterization of the Subcellular Distribution Properties of Human RNA Binding Proteins
Roy R. Parker,
HHMI/University of Colorado, USA
Stress Granules, P-Bodies
Stress Granules, P-Bodies
Markus Landthaler,
Max-Delbrück-Center for Molecular Medicine, Germany
Exploring Global Changes in Protein-mRNA Interactions
Exploring Global Changes in Protein-mRNA Interactions
Coffee Break
Christine Mayr,
Memorial Sloan Kettering Cancer Center, USA
3'UTR-Mediated Protein-Protein Interactions Regulate Protein Functions
3'UTR-Mediated Protein-Protein Interactions Regulate Protein Functions
Jessica Sheu-Gruttadauria,
The Scripps Research Institute, USA
Short Talk: Phase Separation Facilitates MicroRNA Mediated Gene Silencing
Short Talk: Phase Separation Facilitates MicroRNA Mediated Gene Silencing
14:30—16:30
Workshop 1: Recent Observations of Noncoding RNAs, from Function to Therapeutic Modulation
*
Gregory J. Goodall,
SA Pathology, Australia
*
Ling-Ling Chen,
Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, China
Paulo P. Amaral,
University of Cambridge, UK
Genomic Positional Conservation Identifies Topological Anchor Point (tap)RNAs Linked to Developmental Loci
Genomic Positional Conservation Identifies Topological Anchor Point (tap)RNAs Linked to Developmental Loci
Orna Issler,
Mount Sinai School of Medicine, USA
The Role of Long Non-Coding RNAs in Depression
The Role of Long Non-Coding RNAs in Depression
Martin Sauvageau,
Montreal Clinical Research Institute - IRCM, Canada
The Tug1 lncRNA Locus is Essential for Male Fertility and Harbors a cis Repressive Element
The Tug1 lncRNA Locus is Essential for Male Fertility and Harbors a cis Repressive Element
Igor Ulitsky,
Weizmann Institute of Science, Israel
A Subset of Conserved Mammalian Long Noncoding RNAs are Fossils of Ancestral Protein-Coding Genes
A Subset of Conserved Mammalian Long Noncoding RNAs are Fossils of Ancestral Protein-Coding Genes
Mohamed Fareh,
Delft University of Technology, Netherlands
Single-Molecule Fluorescence Reveals how Dicer-TRBP Recognizes Precursor microRNA in Crowded Cellular Environment
Single-Molecule Fluorescence Reveals how Dicer-TRBP Recognizes Precursor microRNA in Crowded Cellular Environment
Benjamin R. Hawley,
Weill Cornell Medicine, USA
A Novel Role for the microRNA Biogenesis Apparatus in the Repair of DNA Double-Strand Breaks
A Novel Role for the microRNA Biogenesis Apparatus in the Repair of DNA Double-Strand Breaks
Puri Fortes,
Foundation for Applied Medical Research, Spain
Antiviral Long Non-Coding RNA EGOT Functions as a Proviral Factor after HCV Infection
Antiviral Long Non-Coding RNA EGOT Functions as a Proviral Factor after HCV Infection
Kaitlyn Rinehold Scacalossi,
New York University, USA
LncRNA CHROME Interacts with DNA to Regulate Transcription of Inflammatory Genes
LncRNA CHROME Interacts with DNA to Regulate Transcription of Inflammatory Genes
Following Session is for Protein-RNA Interactions: Scale, Mechanisms, Structure and Function of Coding and Noncoding RNPs (J6)
14:30—16:30
Workshop 1: RNA Localization in Development and Disease
*
Karla M. Neugebauer,
Yale University, USA
Sahar Soltanieh,
Institut de Recherches Cliniques de Montréal, Canada
Defining the RNA Binding Protein Repertoire of Stress Granules
Defining the RNA Binding Protein Repertoire of Stress Granules
Michaela Müller-McNicoll,
Goethe University Frankfurt, Germany
Cell Type-Specific NucleoCcytoplasmic Shuttling of SR Proteins Reveals Distinct Constellations of RNA-and Protein-Interactors
Cell Type-Specific NucleoCcytoplasmic Shuttling of SR Proteins Reveals Distinct Constellations of RNA-and Protein-Interactors
Takeshi Chujo,
Hokkaido University, Japan
Remarkable Semi-Extractability as the Hallmark of Nuclear Body-Associated Architectural Long Noncoding RNAs
Remarkable Semi-Extractability as the Hallmark of Nuclear Body-Associated Architectural Long Noncoding RNAs
Anastasios Vourekas,
University of Pennsylvania, USA
The Role of RNA Helicase DDX3X in the Activation of HIV Replication in Latently Infected T Cells
The Role of RNA Helicase DDX3X in the Activation of HIV Replication in Latently Infected T Cells
Arnaud Hubstenberger,
Institute of Biology Valrose, France
P-Bodies Condense Coordinately Repressed mRNA Regulons
P-Bodies Condense Coordinately Repressed mRNA Regulons
Lilli Olgeiser,
Heinrich-Heine-University, Germany
Transcriptome-Wide Analysis of Endosomal mRNP Transport
Transcriptome-Wide Analysis of Endosomal mRNP Transport
Louis Philip Benoit Bouvrette,
Universite de Montreal, Canada
Systematic Characterization of Subcellular RNA Localization Through Fractionation-Sequencing
Systematic Characterization of Subcellular RNA Localization Through Fractionation-Sequencing
Eric T. Wang,
University of Florida, USA
Impeding Transcription of Expanded Microsatellite Repeats by dCas9
Impeding Transcription of Expanded Microsatellite Repeats by dCas9
17:00—19:00
Molecular Mechanisms of ncRNA-Protein Interactions in Disease
*
Archa Fox,
University of Western Australia, Australia
Judy Lieberman,
Harvard University, USA
Shooting the Messenger: Rapid and Global mRNA Decay in Apoptosis
Shooting the Messenger: Rapid and Global mRNA Decay in Apoptosis
Gregory J. Goodall,
SA Pathology, Australia
Circular RNAs Regulated during Epithelial-Mesenchymal Transition
Circular RNAs Regulated during Epithelial-Mesenchymal Transition
Tetsuro Hirose,
Osaka University, Japan
Short Talk: Liquid-Liquid Phase Separation and Paraspeckle Formation Induced by the Specific Region of NEAT1 lncRNA
Short Talk: Liquid-Liquid Phase Separation and Paraspeckle Formation Induced by the Specific Region of NEAT1 lncRNA
Following Session is for Protein-RNA Interactions: Scale, Mechanisms, Structure and Function of Coding and Noncoding RNPs (J6)
17:00—19:15
Protein-RNA Recognition: Structural, Biochemical and Computational
*
Zefeng Wang,
CAS-MPG Partner Institute of Computational Biology, China
Frédéric H.T. Allain,
ETH Zurich, Switzerland
Structures of Protein RNA Complexes using Hybrid Structural Approaches
Structures of Protein RNA Complexes using Hybrid Structural Approaches
Clara L. Kielkopf,
University of Rochester Center for RNA Biology, USA
Structures of pre-mRNA Splicing Factors in Cancer
Structures of pre-mRNA Splicing Factors in Cancer
Joel R. Neilson,
Baylor College of Medicine, USA
CELF1 is a Central Node in Post-transcriptional Regulatory Programs Underlying EMT
CELF1 is a Central Node in Post-transcriptional Regulatory Programs Underlying EMT
Linnea Jansson,
University of California, Santa Cruz, USA
Short Talk: Probing the Structure and Function of Human Telomerase
Short Talk: Probing the Structure and Function of Human Telomerase
Ralf Ficner,
University of Goettingen, Germany
Short Talk: Structural Insights into the Mechanism of DEAH-box RNA Helicases
Short Talk: Structural Insights into the Mechanism of DEAH-box RNA Helicases
08:00—11:15
Nucleic Acid-Based Strategies to Disrupt ncRNA and Gene Interactions
*
Judy Lieberman,
Harvard University, USA
Kevin V. Morris,
Center for Gene Therapy, City of Hope, USA
Functional Roles of RNA in Nucleotide Content, Selection and Gene Evolution
Functional Roles of RNA in Nucleotide Content, Selection and Gene Evolution
Claes Wahlestedt,
University of Miami, Miller School of Medicine, USA
Gene Upregulation by Targeting Long Noncoding RNAs
Gene Upregulation by Targeting Long Noncoding RNAs
Coffee Break
David R. Corey,
University of Texas Southwestern Medical Center, USA
Control of lncRNA Function by Small RNAs
Control of lncRNA Function by Small RNAs
Kim A. Lennox,
Integrated DNA Technologies, USA
Optimal Knockdown of Long Noncoding RNAs Is Dependent on Subcellular Localization: RNAi versus Antisense
Optimal Knockdown of Long Noncoding RNAs Is Dependent on Subcellular Localization: RNAi versus Antisense
Ben Berkhout,
University of Amsterdam, Academic Medical Center, Netherlands
Short Talk: A Combinatorial CRISPR-Cas9 Attack on HIV-1 DNA Extinguishes all Infectious Provirus in Infected T Cell Cultures
Short Talk: A Combinatorial CRISPR-Cas9 Attack on HIV-1 DNA Extinguishes all Infectious Provirus in Infected T Cell Cultures
Ankit Bhatta,
University of Massachusetts Medical School, USA
Short Talk: An Immune Regulated Annotated Long Noncoding RNA Encodes a Mitochondrial Micropeptide
Short Talk: An Immune Regulated Annotated Long Noncoding RNA Encodes a Mitochondrial Micropeptide
Following Session is for Protein-RNA Interactions: Scale, Mechanisms, Structure and Function of Coding and Noncoding RNPs (J6)
08:00—11:00
Coding and Noncoding RNP Complexes
*
Eric Lecuyer,
Institut de Recherches Cliniques de Montreal, Canada Joint Institute, Canada
Susan Baserga,
Yale University School of Medicine, USA
Using Cryo-Electron Microscopy to Discover Box C/D s(no)RNP Structure
Using Cryo-Electron Microscopy to Discover Box C/D s(no)RNP Structure
Jeannie T. Lee,
Massachusetts General Hospital / Harvard Medical School, USA
Interaction of RNA with Polycomb Complexes: Regulation, Function and Cellular Consequences
Interaction of RNA with Polycomb Complexes: Regulation, Function and Cellular Consequences
Coffee Break
Jeffrey A. Chao,
Friedrich Miescher Institute for Biomedical Research, Switzerland
Imaging the Life and Death of mRNAs in Single Cells
Imaging the Life and Death of mRNAs in Single Cells
Melissa Jurica,
University of California, Santa Cruz, USA
The Dynamic Architecture of Human Spliceosomes
The Dynamic Architecture of Human Spliceosomes
Olivia Rissland,
University of Colorado School of Medicine, USA
Short Talk: Widespread Reorganization of mRNA-Protein Complexes at the Mid-Blastula Transition
Short Talk: Widespread Reorganization of mRNA-Protein Complexes at the Mid-Blastula Transition
14:30—16:30
Workshop 2: Synthetic Nucleic Acids, Targeted Approaches to Disrupting Noncoding RNA Pathways in Disease
*
Tetsuro Hirose,
Osaka University, Japan
*
David R. Corey,
University of Texas Southwestern Medical Center, USA
Jan Gorodkin,
University of Copenhagen, Denmark
From Fast Computational Screen for RNA-RNA Interactions to siRNA Off-Target Prediction
From Fast Computational Screen for RNA-RNA Interactions to siRNA Off-Target Prediction
John Liu,
University of California, San Francisco, USA
Genome-Scale CRISPRi-Based Screening of lncRNAs Reveals Radiation Sensitizers for Glioma Therapy
Genome-Scale CRISPRi-Based Screening of lncRNAs Reveals Radiation Sensitizers for Glioma Therapy
Guia Guffanti,
Harvard Medical School, USA
Differential Expression of Long Non-Coding RNA GAS5 in Post-Traumatic Stress Disorder
Differential Expression of Long Non-Coding RNA GAS5 in Post-Traumatic Stress Disorder
Claudia Lang,
Plant and Food Research, New Zealand
Genetic Variants of Plant MicroRNA miR168a Can Affect Regulatory Function with the Human Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1) Transcript in vitro
Genetic Variants of Plant MicroRNA miR168a Can Affect Regulatory Function with the Human Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1) Transcript in vitro
Li Yang,
CAS-MPG Partner Institute for Computational Biology, China
Alternative Back-Splicing Landscape of circRNAs
Alternative Back-Splicing Landscape of circRNAs
Jennifer Perez Boza,
University of Liège, Belgium
The RNA Sub-Classes Distribution of Small RNAs Differs Between Cells and Exosomes
The RNA Sub-Classes Distribution of Small RNAs Differs Between Cells and Exosomes
Following Session is for Protein-RNA Interactions: Scale, Mechanisms, Structure and Function of Coding and Noncoding RNPs (J6)
14:30—16:30
Workshop 2: Coupling between Transcription and Post-Transcriptional Processes
*
Markus Landthaler,
Max-Delbrück-Center for Molecular Medicine, Germany
Yael Mandel-Gutfreund,
Technion – Israel Institute of Technology, Israel
Revealing the Role of Dual DNA and RNA Binding Proteins in Human Embryonic Stem Cells
Revealing the Role of Dual DNA and RNA Binding Proteins in Human Embryonic Stem Cells
Philipp Neumann,
Goethe-University, Germany
The Antisense Transcript of GATA6 Interacts With The H3K4me3 Deaminase LOXL2 and Epigenetically Regulates Endothelial Gene Expression
The Antisense Transcript of GATA6 Interacts With The H3K4me3 Deaminase LOXL2 and Epigenetically Regulates Endothelial Gene Expression
Giorgia Benegiamo,
The Salk Institute for Biological Studies, USA
NONO Coordinates Pre-mRNA Processing with Fasting/Feeding Cycles in the Mouse Liver
NONO Coordinates Pre-mRNA Processing with Fasting/Feeding Cycles in the Mouse Liver
William J. Martin,
Vanderbilt University, USA
Structure-Specific Recognition of a G-Quadruplex RNA by the Histone Demethylase LSD1
Structure-Specific Recognition of a G-Quadruplex RNA by the Histone Demethylase LSD1
John A. Smolka,
University of California, Davis, USA
Proteomic Identification and Functional Investigation of Novel Factors and Pathways in RNA:DNA Hybrid Metabolism
Proteomic Identification and Functional Investigation of Novel Factors and Pathways in RNA:DNA Hybrid Metabolism
Wei Zhang,
Albany Medical College, USA
A Vascular Smooth Muscle-Enriched Long Non-coding RNA (MELRI) Interacts with Myocardin-Related Transcription Factor A and Promotes Inflammation
A Vascular Smooth Muscle-Enriched Long Non-coding RNA (MELRI) Interacts with Myocardin-Related Transcription Factor A and Promotes Inflammation
Nabieh Ayoub,
Technion -Israel Institute of Technology, Israel
High-Throughput Mapping of the RNA Interacting Molecules of KDM4 Lysine Demethylases
High-Throughput Mapping of the RNA Interacting Molecules of KDM4 Lysine Demethylases
17:00—19:00
RNA and DNA Control of Genes and Gene Networks in Disease
*
Adrian R. Krainer,
Cold Spring Harbor Laboratory, USA
Ling-Ling Chen,
Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, China
The Diversity of Sno-processed lncRNAs and their Roles in Gene Regulation
The Diversity of Sno-processed lncRNAs and their Roles in Gene Regulation
Jean-Jacques Toulme,
University of Bordeaux, France
Aptamer-Based Riboswitches
Aptamer-Based Riboswitches
Jacob M. Berlin,
Beckman Research Institute of City of Hope, USA
Small Molecule Targeting of Regulatory lncRNAs
Small Molecule Targeting of Regulatory lncRNAs
Stuart F.J. Le Grice,
NCI, National Institutes of Health, USA
Short Talk: Small Molecule Targeting of KSHV Polyadenylated Nuclear RNA (PAN)
Short Talk: Small Molecule Targeting of KSHV Polyadenylated Nuclear RNA (PAN)
Following Session is for Protein-RNA Interactions: Scale, Mechanisms, Structure and Function of Coding and Noncoding RNPs (J6)
17:00—19:15
RNA Landscape and Conformation at Scale: Interaction and Function
*
Jeffrey A. Chao,
Friedrich Miescher Institute for Biomedical Research, Switzerland
Robert Spitale,
University of California, Irvine, USA
Chemo-Transcriptomic Methods to Measure RNA Structure inside Living Cells
Chemo-Transcriptomic Methods to Measure RNA Structure inside Living Cells
Yue Wan,
Genome Institute of Singapore, Singapore
In vivo Mapping of Eukaryotic RNA Interactomes Reveals Principles of Higher-order Organization and Regulation
In vivo Mapping of Eukaryotic RNA Interactomes Reveals Principles of Higher-order Organization and Regulation
Jernej Ule,
Francis Crick Institute & UCL, UK
Exon Junction Complex Inhibits Recursive Splicing of Canonical Exons
Exon Junction Complex Inhibits Recursive Splicing of Canonical Exons
Mihir Metkar,
University of Massachusetts Medical School, USA
Short Talk: Understanding Higher Order Structure of Spliced RNPs
Short Talk: Understanding Higher Order Structure of Spliced RNPs
Yoosik Kim,
Korea Advanced Institute of Science and Technology, South Korea
Short Talk: PKR is Activated by Mitochondrial ncRNAs and Serves as a Coordinator of Mitochondrial-Nuclear Communication
Short Talk: PKR is Activated by Mitochondrial ncRNAs and Serves as a Coordinator of Mitochondrial-Nuclear Communication
19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.
08:00—11:15
Synthetic RNAs: From Evolution to Catalysis to Functional Gene Targeting
*
Ryszard Kole,
Ercole Biotech Consulting, USA
Muthiah Manoharan,
Alnylam Pharmaceuticals, Inc., USA
RNAi Therapeutics: From Discovery to Applications
RNAi Therapeutics: From Discovery to Applications
Coffee Break
Adrian R. Krainer,
Cold Spring Harbor Laboratory, USA
Mechanism-Based Antisense Therapeutics Targeting Splicing or NMD
Mechanism-Based Antisense Therapeutics Targeting Splicing or NMD
Paolo G. V. Martini,
Moderna, USA
Messenger RNA Therapy for Monogenic Disorders
Messenger RNA Therapy for Monogenic Disorders
Brian H. Johnston,
Somagenics Inc., USA
Short Talk: Local delivery of sshRNAs Accelerate Wound Healing in Diabetic Mice
Short Talk: Local delivery of sshRNAs Accelerate Wound Healing in Diabetic Mice
Following Session is for Protein-RNA Interactions: Scale, Mechanisms, Structure and Function of Coding and Noncoding RNPs (J6)
08:00—11:00
RNA Modifications of Noncoding and Coding RNAs
*
Melissa Jurica,
University of California, Santa Cruz, USA
Jeremy E. Wilusz,
University of Pennsylvania, USA
Regulation of MALAT1 and Other Non-Polyadenylated RNAs
Regulation of MALAT1 and Other Non-Polyadenylated RNAs
Coffee Break
Wendy V. Gilbert,
Massachusetts Institute of Technology, USA
Regulated RNA Modifications
Regulated RNA Modifications
Marie Ohman,
Stockholm University, Sweden
Short Talk: RNA Editing Regulates Synaptic miRNAs
Short Talk: RNA Editing Regulates Synaptic miRNAs
17:00—19:00
Therapeutic Approaches to Disrupting or Mimicking lncRNA Function
*
Paloma Giangrande,
Moderna, USA
Stefano Gustincich,
Italian Institute of Technology, Italy
SINEUPs: A New Class of Natural and Synthetic Antisense Long Noncoding RNAs that Activate Translation
SINEUPs: A New Class of Natural and Synthetic Antisense Long Noncoding RNAs that Activate Translation
Ryszard Kole,
Ercole Biotech Consulting, USA
PMO Targeting of mRNAs in Human Disease
PMO Targeting of mRNAs in Human Disease
Fabio Romerio,
University of Maryland School of Medicine, USA
The HIV-1 Antisense Transcript AST Promotes Latency by Recruiting PRC2 to the 5'LTR
The HIV-1 Antisense Transcript AST Promotes Latency by Recruiting PRC2 to the 5'LTR
Jonathan T. Sczepanski,
Texas A&M University, USA
Short Talk: Mirror-Image Aptamers with Expanded Functionality for Targeting RNA Structures
Short Talk: Mirror-Image Aptamers with Expanded Functionality for Targeting RNA Structures
Following Session is for Protein-RNA Interactions: Scale, Mechanisms, Structure and Function of Coding and Noncoding RNPs (J6)
17:00—19:15
Molecular Engineering of RNA and Protein Complexes
*
Robert Spitale,
University of California, Irvine, USA
Zefeng Wang,
CAS-MPG Partner Institute of Computational Biology, China
Manipulation of RNA Metabolism Using Engineered Proteins
Manipulation of RNA Metabolism Using Engineered Proteins
Samie Jaffrey,
Weill Medical College of Cornell University, USA
Imaging Cellular Messengers with Genetically Encoded Sensors Composed of Circular RNA
Imaging Cellular Messengers with Genetically Encoded Sensors Composed of Circular RNA
Stephen N. Floor,
University of California, Berkeley, USA
Measuring and Engineering Translation at Transcript Isoform Resolution
Measuring and Engineering Translation at Transcript Isoform Resolution
Kinjal Ashokbhai Patel,
National Institute of Pharmaceutical Education and Research, India
Short Talk: Interaction of RNA Aptamers with Mutant Huntingtin Protein: Implication for Protein Aggregation and Mitochondrial Function in Huntington’s Disease
Short Talk: Interaction of RNA Aptamers with Mutant Huntingtin Protein: Implication for Protein Aggregation and Mitochondrial Function in Huntington’s Disease
Sarah Denny,
Stanford University, USA
Short Talk: High-throughput, Quantitative Characterization of Modular Elements of RNA Tertiary Structure
Short Talk: High-throughput, Quantitative Characterization of Modular Elements of RNA Tertiary Structure
19:15—20:15
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.
20:00—23:00
Entertainment
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.
*Session Chair †Invited, not yet responded.
We gratefully acknowledge support for this conference from:
Keystone Symposia thanks our Sponsors(s) for generously supporting this meeting:
![]() |
![]() |
![]() |
![]() |
We gratefully acknowledge the generous grant for this conference provided by:
We gratefully acknowledge additional support for this conference from:
![]() |
![]() |
![]() |
![]() |
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:
Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:
Click here to view more of these organizations
If your organization is interested in joining these entities in support of Keystone
Symposia, please contact: Sarah Lavicka,
Director of Corporate Relations, Email: sarahl@keystonesymposia.org, Phone:+1 970-262-2690 Click here for more information on Industry Support and Recognition Opportunities. If you are interested in becoming an advertising/marketing in-kind partner, please contact: Nick Dua, Senior Director, Communications, Email: nickd@keystonesymposia.org, Phone:+1 970-262-1179 |