Lee Shau Kee Lecture Centre, Centennial Campus University of Hong Kong Floorplan
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This meeting took place in 2018
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Framing the Response to Emerging Virus Infections (S2)
Organizer(s) Ralph A. Tripp, Suresh Mahalingam, John W. Lowenthal, Andrew G. Bean and Malik Peiris
October 14—18, 2018
Lee Shau Kee Lecture Centre, Centennial Campus University of Hong Kong • Pok Fu Lam, Hong Kong
Discounted Abstract Deadline: Jun 27, 2018
Abstract Deadline: Jul 17, 2018
Scholarship Deadline: Jun 27, 2018
Discounted Registration Deadline: Aug 14, 2018
Organized in collaboration with the Croucher Foundation and The University of Hong Kong
Summary of Meeting:
Emerging and re-emerging viruses have the potential to cause high morbidity and mortality and range from localized outbreaks to epidemics. Due to their emerging nature, most aspects of the biology and infectious potential of these viruses are poorly understood. Our continuing struggle to respond to a procession of pandemics including SARS, avian influenza, MERS, Ebola and more recently Zika, highlights key gaps in our knowledge and should serve to motivate our re-thinking on how we can better prepare and deal with future unknown viral threats. This meeting will focus on important areas such as surveillance, diagnostics and countermeasures and other important advances in new technologies and how they are being applied to research. Furthermore, we will discuss how to facilitate the translation of research, data and candidate treatments through the development pipeline in a timely and cost-effective manner. The key themes to be covered include the need to understand why zoonotic diseases matter, their association with agriculture, the importance of surveillance and early detection, and the difficulties of dealing with diseases that involve both medical and veterinary communities. The conference will bring together experts in virology, immunology, vaccinology, epidemiology with those that seek to transfer knowledge between these groups, veterinarians and industry and government. Further, this meeting would bring together individuals involved in the control of these diseases in government and non-government organizations, as well as people involved in study of zoonosis and countermeasures. The creation of global networks and sharing of information will ensure that we are better prepared for future outbreaks.
View Scholarships/Awards
Emerging and re-emerging viruses have the potential to cause high morbidity and mortality and range from localized outbreaks to epidemics. Due to their emerging nature, most aspects of the biology and infectious potential of these viruses are poorly understood. Our continuing struggle to respond to a procession of pandemics including SARS, avian influenza, MERS, Ebola and more recently Zika, highlights key gaps in our knowledge and should serve to motivate our re-thinking on how we can better prepare and deal with future unknown viral threats. This meeting will focus on important areas such as surveillance, diagnostics and countermeasures and other important advances in new technologies and how they are being applied to research. Furthermore, we will discuss how to facilitate the translation of research, data and candidate treatments through the development pipeline in a timely and cost-effective manner. The key themes to be covered include the need to understand why zoonotic diseases matter, their association with agriculture, the importance of surveillance and early detection, and the difficulties of dealing with diseases that involve both medical and veterinary communities. The conference will bring together experts in virology, immunology, vaccinology, epidemiology with those that seek to transfer knowledge between these groups, veterinarians and industry and government. Further, this meeting would bring together individuals involved in the control of these diseases in government and non-government organizations, as well as people involved in study of zoonosis and countermeasures. The creation of global networks and sharing of information will ensure that we are better prepared for future outbreaks.
View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference
The meeting will begin on Sunday, October 14 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, October 18 with a closing plenary session from 13:30 to 18:30, followed by dinner. We recommend return travel on Friday, October 19 in order to fully experience the meeting.
SUNDAY, OCTOBER 14
MONDAY, OCTOBER 15
TUESDAY, OCTOBER 16
WEDNESDAY, OCTOBER 17
THURSDAY, OCTOBER 18
FRIDAY, OCTOBER 19
Conference Program Print | View meeting in 12 hr (am/pm) time
The meeting will begin on Sunday, October 14 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, October 18 with a closing plenary session from 13:30 to 18:30, followed by dinner. We recommend return travel on Friday, October 19 in order to fully experience the meeting.
SUNDAY, OCTOBER 14
16:00—20:00
Arrival and Registration
Hotel Jen Lobby
18:00—20:00
Welcome Mixer
No registration fees are used to fund alcohol served at this function.
Hotel Jen Lobby
08:00—09:00
Poster Setup
Lecture Hall LG 2
09:00—17:30
Poster Viewing
Lecture Hall LG 2
09:00—10:00
Welcome and Keynote Address
Grand Hall
*
Malik Peiris,
University of Hong Kong, Hong Kong
Gabriel M. Leung,
University of Hong Kong, Hong Kong
Opening Remarks
Opening Remarks
Peter Daszak,
EcoHealth Alliance, USA
Emerging Infectious Disease Threats
Emerging Infectious Disease Threats
10:00—12:30
Mosquito-Borne Viruses - Biology and Host Interactions
Grand Hall
*
Lisa E. Gralinski,
University of North Carolina, USA
Scott C. Weaver,
University of Texas Medical Branch, USA
Urban Arboviruses: History, Evolution and Mechanisms of Emergence
Urban Arboviruses: History, Evolution and Mechanisms of Emergence
Coffee Break
Suresh Mahalingam,
Griffith University, Australia
Alphavirus Inflammatory Disease Mechanisms and Approaches to Therapy
Alphavirus Inflammatory Disease Mechanisms and Approaches to Therapy
Michael S. Diamond,
Washington University School of Medicine, USA
Host Factors Required for Alphavirus Infection: The Identification of Mxra8 as an Entry Receptor
Host Factors Required for Alphavirus Infection: The Identification of Mxra8 as an Entry Receptor
Ali Zaid,
Griffith University Gold Coast, Australia
Short Talk: Specific Inhibition of NLRP3 in Chikungunya Disease Reveals a Role for Inflammasome in Alphavirus-Induced Inflammation
Short Talk: Specific Inhibition of NLRP3 in Chikungunya Disease Reveals a Role for Inflammasome in Alphavirus-Induced Inflammation
Kar Muthumani,
Wistar Institute, USA
Short Talk: Synthetic Nucleic Acid Antibody Prophylaxis + DNA Vaccine Confers Rapid and Durable Protective Immunity against Zika Virus
Short Talk: Synthetic Nucleic Acid Antibody Prophylaxis + DNA Vaccine Confers Rapid and Durable Protective Immunity against Zika Virus
12:30—13:30
Networking Lunch
Lecture Hall LG 2
13:00—15:00
Poster Session 1
Lecture Hall LG 2
15:00—15:30
Coffee Available
Lecture Hall LG 2
15:30—17:30
ZIKA Virus Countermeasures
Grand Hall
*
Suresh Mahalingam,
Griffith University, Australia
Raman Rao,
Takeda Pharmaceutical Company, Singapore
Zika Vaccine Development Strategies for Emergency Preparedness
Zika Vaccine Development Strategies for Emergency Preparedness
Mauro Martins Teixeira,
Universidade Federal de Minas Gerais, Brazil
The Role of Glutamate Receptors in the Pathogenesis of Zika
The Role of Glutamate Receptors in the Pathogenesis of Zika
Natalie A. Prow,
University of South Australia, Australia
A New Replication-Defective, Vaccinia-Derived, CHO-Manufactured Vaccine Vector System (SCV) Is Effective in Preclinical Studies against Zika and Chikungunya Viruses
A New Replication-Defective, Vaccinia-Derived, CHO-Manufactured Vaccine Vector System (SCV) Is Effective in Preclinical Studies against Zika and Chikungunya Viruses
Mingyuan Li,
University of Hong Kong, Hong Kong
Short Talk: Activated ADP-Ribosylation Factor 4 (ARF4) Is Required for ZIKA Virus (ZIKV) Infectious Cycle
Short Talk: Activated ADP-Ribosylation Factor 4 (ARF4) Is Required for ZIKA Virus (ZIKV) Infectious Cycle
08:30—09:00
Poster Setup
Lecture Hall LG 2
09:00—17:00
Poster Viewing
Lecture Hall LG 2
09:00—10:30
Ebola Virus: Biology and Host Interactions
Grand Hall
*
Erica Ollmann Saphire,
La Jolla Institute for Immunology, USA
Yoshihiro Kawaoka,
University of Wisconsin / University of Tokyo, USA
Human Ebola Virus Disease Pathogenesis Revealed by Multi-Platform ‘Omics Analysis
Human Ebola Virus Disease Pathogenesis Revealed by Multi-Platform ‘Omics Analysis
Andrea Marzi,
NIAID, National Institutes of Health, USA
Animal Models of Ebolaviruses
Animal Models of Ebolaviruses
Adam Joseph Hume,
Boston University, USA
Short Talk: The Use of Minigenome Systems as Tools to “Fill in the Blanks” for Uncultured Emerging Viruses and Facilitate Virus Rescue: A Lloviu Virus Case Study
Short Talk: The Use of Minigenome Systems as Tools to “Fill in the Blanks” for Uncultured Emerging Viruses and Facilitate Virus Rescue: A Lloviu Virus Case Study
Beatriz Escudero Pérez,
Bernhard Nocht Institute for Tropical Medicine, Germany
Short Talk: Comparative Pathogenesis of Ebola and Reston Virus in Humanized Mice
Short Talk: Comparative Pathogenesis of Ebola and Reston Virus in Humanized Mice
Coffee Break
10:50—12:30
Ebola Virus: Vaccines and Therapeutics
Grand Hall
*
Andrea Marzi,
NIAID, National Institutes of Health, USA
Erica Ollmann Saphire,
La Jolla Institute for Immunology, USA
Structural Studies to Guide the Development of Broadly Reactive Antibodies Against Ebolaviruses and Lassa Virus
Structural Studies to Guide the Development of Broadly Reactive Antibodies Against Ebolaviruses and Lassa Virus
John Misasi,
NIAID, National Institutes of Health, USA
Short Talk: ChAd3-Based Ebola Vaccination Induces Protective Antibody Classes
Short Talk: ChAd3-Based Ebola Vaccination Induces Protective Antibody Classes
Sarah Elliott,
Wistar Institute, USA
Short Talk: A Synthetic Micro-Consensus DNA Vaccine Induces Potent Immune Responses Against Diverse Strains of Marburgvirus
Short Talk: A Synthetic Micro-Consensus DNA Vaccine Induces Potent Immune Responses Against Diverse Strains of Marburgvirus
Danielle P. Porter,
Gilead Sciences, USA
Short Talk: Broad Spectrum Antiviral Remdesivir for the Treatment of Emerging Viral Infections with High Outbreak Potential
Short Talk: Broad Spectrum Antiviral Remdesivir for the Treatment of Emerging Viral Infections with High Outbreak Potential
12:30—13:30
Lunch
Lecture Hall LG 2
13:00—15:00
Poster Session 2
Lecture Hall LG 2
14:30—15:00
Coffee Available
Lecture Hall LG 2
15:00—17:00
Zoonotic Influenza and MERS
Grand Hall
*
Andrew G. Bean,
Commonwealth Scientific and Industrial Research Organization, Australia
Yi Guan,
University of Hong Kong, Hong Kong
Zoonotic Influenza Viruses from China: An Increasing Pandemic Threat?
Zoonotic Influenza Viruses from China: An Increasing Pandemic Threat?
Malik Peiris,
University of Hong Kong, Hong Kong
MERS-Coronaviruses in Africa - Is There a Zoonotic Threat?
MERS-Coronaviruses in Africa - Is There a Zoonotic Threat?
LaiGiea Nicole Seng,
University of Hong Kong, Hong Kong
Short Talk: Virulence Determinants of Novel Influenza A (H7N9) Virus in Mammals
Short Talk: Virulence Determinants of Novel Influenza A (H7N9) Virus in Mammals
Sabiha Jahan Akhee,
University of Hong Kong, Hong Kong
Short Talk: Deubiquitylase OTUB1 Plays Critical Role in Influenza A Virus Infection and Immune Response
Short Talk: Deubiquitylase OTUB1 Plays Critical Role in Influenza A Virus Infection and Immune Response
18:00—18:30
Transportation to Optional Dinner
18:30—21:30
Optional Dinner Gathering at Jumbo Kingdom
09:00—12:30
MERS
Grand Hall
*
John W. Lowenthal,
Deakin University, Australia
KY Yuen,
University of Hong Kong, Hong Kong
Host Cellular Protein Facilitating Viral Replication
Host Cellular Protein Facilitating Viral Replication
Ralph S. Baric,
University of North Carolina at Chapel Hill, USA
Rapid Response Strategies to Control Emerging Coronavirus Infections
Rapid Response Strategies to Control Emerging Coronavirus Infections
Dong-Yan Jin,
University of Hong Kong, Hong Kong
Short Talk: Suppression of Type I Interferon Production by Middle East Respiratory Syndrome Coronavirus ORF8b Accessory Protein through Interaction with HSP70 Chaperone
Short Talk: Suppression of Type I Interferon Production by Middle East Respiratory Syndrome Coronavirus ORF8b Accessory Protein through Interaction with HSP70 Chaperone
Lisa E. Gralinski,
University of North Carolina, USA
Short Talk: Using a Reduced Complexity Cross to Identify Host Susceptibility Factors to SARS-CoV Infection
Short Talk: Using a Reduced Complexity Cross to Identify Host Susceptibility Factors to SARS-CoV Infection
Coffee Break
*
Bart L. Haagmans,
Erasmus MC, Netherlands
John W. Lowenthal,
Deakin University, Australia
A Strategy for Developing a MERS Camel Vaccine in Order to Protect Humans
A Strategy for Developing a MERS Camel Vaccine in Order to Protect Humans
Jincun Zhao,
Guangzhou Institute of Respiratory Disease, China
Immune Responses in MERS-CoV Infected Mice and Humans
Immune Responses in MERS-CoV Infected Mice and Humans
Stalin Raj Victor,
Indian Institute of Science Education and Research, India
Short Talk: Chimeric Camel-Human Heavy Chain Antibodies Protect Mice from MERS-CoV Infection
Short Talk: Chimeric Camel-Human Heavy Chain Antibodies Protect Mice from MERS-CoV Infection
Neeltje van Doremalen,
NIAID, National Institutes of Health, USA
Short Talk: The Omics of Sex-Specific MERS-CoV Severity in a Transgenic Mouse Model
Short Talk: The Omics of Sex-Specific MERS-CoV Severity in a Transgenic Mouse Model
12:30—13:00
Poster Setup
Lecture Hall LG 2
12:30—17:00
On Own for Lunch and Recreation
13:00—21:30
Poster Viewing
Lecture Hall LG 2
16:30—17:00
Coffee Available
Lecture Hall LG 2
17:00—19:00
Emerging Disease Detection and Surveillance
Grand Hall
Marion P.G. Koopmans,
Erasmus MC, Netherlands
Challenges and Opportunities in Emerging Disease Detection
Challenges and Opportunities in Emerging Disease Detection
Gavin J.D. Smith,
Duke-NUS Medical School, Singapore
Surveillance for Risk Assessment and Prediction
Surveillance for Risk Assessment and Prediction
Linfa Wang,
Duke-NUS Medical School, Singapore
From SARS to SADS: EIDs Caused by Bat Coronaviruses
From SARS to SADS: EIDs Caused by Bat Coronaviruses
Anna Uehara,
Duke-NUS Medical School, Singapore
Short Talk: Serologic Evidence of Bat Orthoreovirus in Singapore
Short Talk: Serologic Evidence of Bat Orthoreovirus in Singapore
Kenrie Pui Yan Hui,
University of Hong Kong, Hong Kong
Short Talk: Tropism and Pathogenesis of the Avian Influenza A/H7N9 Virus in ex vivo and in vitro Cultures of the Human Respiratory Tract and Human Airway Organoids
Short Talk: Tropism and Pathogenesis of the Avian Influenza A/H7N9 Virus in ex vivo and in vitro Cultures of the Human Respiratory Tract and Human Airway Organoids
19:00—20:00
Social Hour with Lite Bites
Lecture Hall LG 2
19:30—21:30
Poster Session 3
Lecture Hall LG 2
09:00—12:00
Influenza: Immunity and Vaccines
Grand Hall
*
Ralph A. Tripp,
University of Georgia, USA
Leo Poon,
University of Hong Kong, Hong Kong
Universal Influenza Vaccines
Universal Influenza Vaccines
Andrew G. Bean,
Commonwealth Scientific and Industrial Research Organization, Australia
Tailoring the Avian Host Immune Response for Enhanced Vaccine Production
Tailoring the Avian Host Immune Response for Enhanced Vaccine Production
Sophie A. Valkenburg,
University of Hong Kong, Hong Kong
Short Talk: ADCC Antibodies Are a Protective Immune Correlate in a Household Model of Influenza Transmission
Short Talk: ADCC Antibodies Are a Protective Immune Correlate in a Household Model of Influenza Transmission
Matloob Husain,
University of Otago, New Zealand
Short Talk: The Identification of Human Histone Deacetylases, HDAC1 and HDAC2 as Novel Anti-Influenza Viral Factors
Short Talk: The Identification of Human Histone Deacetylases, HDAC1 and HDAC2 as Novel Anti-Influenza Viral Factors
Coffee Break
*
Linfa Wang,
Duke-NUS Medical School, Singapore
Ted M. Ross,
University of Georgia, USA
Broadly Protective Influenza Vaccines: Protection Against Mismatched Strains
Broadly Protective Influenza Vaccines: Protection Against Mismatched Strains
Li-meng Yan,
University of Hong Kong, Hong Kong
Short Talk: Combined Use of Live-Attenuated and Inactivated Influenza Vaccines to Enhance Heterosubtypic Protection
Short Talk: Combined Use of Live-Attenuated and Inactivated Influenza Vaccines to Enhance Heterosubtypic Protection
Timothy Uyeki,
Centers for Disease Control and Prevention, USA
Short Talk: Clinical Research Is a Major Gap in the Response to Emerging Respiratory Viral Infections
Short Talk: Clinical Research Is a Major Gap in the Response to Emerging Respiratory Viral Infections
12:00—13:30
Lunch
Lecture Hall LG 2
13:30—15:45
Vaccine and Therapeutic Strategies
Grand Hall
*
Marion P.G. Koopmans,
Erasmus MC, Netherlands
Stephen Whitehead,
NIAID, National Institutes of Health, USA
Evaluation of Live Attenuated Vaccines for Dengue and Zika Viruses (and their Challenge Models)
Evaluation of Live Attenuated Vaccines for Dengue and Zika Viruses (and their Challenge Models)
Coffee Break
Adam Taylor,
Griffith University, Australia
Short Talk: Novel Delivery of a Live-Attenuated Chikungunya Virus Vaccine Candidate
Short Talk: Novel Delivery of a Live-Attenuated Chikungunya Virus Vaccine Candidate
James Duehr,
Icahn School of Medicine, USA
Short Talk: Characterization of Humoral Immunity Generated against Andes Virus GnGc
Short Talk: Characterization of Humoral Immunity Generated against Andes Virus GnGc
Danielle E. Anderson,
Duke-NUS Medical School, Singapore
Short Talk: SEC61B Is a Cellular Host Factor Required for Mumps Virus Replication in Humans and Bats
Short Talk: SEC61B Is a Cellular Host Factor Required for Mumps Virus Replication in Humans and Bats
Laura Riva,
Sanford Burnham Prebys Medical Discovery Institute, USA
Short Talk: Identification of Chemical Compounds Inhibiting Ebola Virus Replication
Short Talk: Identification of Chemical Compounds Inhibiting Ebola Virus Replication
15:45—16:00
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Grand Hall
17:30—18:30
Social Hour
Cafe Malacca, Hotel Jen
18:30—20:00
Buffet Dinner
Cafe Malacca, Hotel Jen
Departure
*Session Chair †Invited, not yet responded.
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