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This meeting took place in 2001
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Signaling Systems: Chemistry, Biology and Pathology (E4)
Organizer(s) Ralph A. Bradshaw, Ann Richmond, Kenneth A. Thomas, Leslie M. Thompson and Christian W. Schindler
April 3—9, 2001
Sheraton Steamboat Resort • Steamboat Springs, CO USA
Abstract Deadline: Dec 4, 2000
Late Abstract Deadline:
Scholarship Deadline:
Early Registration Deadline: Feb 2, 2001
Sponsored in part by the Director's Sponsor Fund
Summary of Meeting:
This meeting will emphasize signaling pathways of all types, with a focus on where they overlap and/or intersect. Particular emphasis on pathologies related to signaling defects as possible targets of intervention will be stressed. The meeting is composed of four levels: receptors and ligands; signaling molecules (adaptors and effectors); gene transcription; and phenotypic/cellular responses (and associated pathologies).
View Scholarships/Awards
This meeting will emphasize signaling pathways of all types, with a focus on where they overlap and/or intersect. Particular emphasis on pathologies related to signaling defects as possible targets of intervention will be stressed. The meeting is composed of four levels: receptors and ligands; signaling molecules (adaptors and effectors); gene transcription; and phenotypic/cellular responses (and associated pathologies).
View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference
TUESDAY, APRIL 3
WEDNESDAY, APRIL 4
THURSDAY, APRIL 5
FRIDAY, APRIL 6
SATURDAY, APRIL 7
SUNDAY, APRIL 8
MONDAY, APRIL 9
Conference Program Print | View meeting in 12 hr (am/pm) time
TUESDAY, APRIL 3
19:30—21:30
Keynote Address
*
Ralph A. Bradshaw,
University of California-Irvine, USA
James E. Darnell,
Rockefeller University, USA
STAT Proteins: Transcriptional Activation and Biologic Import
STAT Proteins: Transcriptional Activation and Biologic Import
Tony Hunter,
The Salk Institute for Biological Sciences, USA
Signaling by Phosphorylation in the Age of Genomics
Signaling by Phosphorylation in the Age of Genomics
08:00—11:00
Receptors/Ligands I
Stevan R. Hubbard,
New York University School of Medicine, USA
Structural Studies of the Insulin Receptor Tyrosine Kinase
Structural Studies of the Insulin Receptor Tyrosine Kinase
*
Tony Pawson,
Samuel Lunenfeld Research Institute, Canada
Wiring the Cell Through Modular Protein-Protein Interactions
Wiring the Cell Through Modular Protein-Protein Interactions
John Kuriyan,
University of California, Berkeley, USA
Auto-Inhibition Mechanisms of Protein Kinases
Auto-Inhibition Mechanisms of Protein Kinases
*
Kenneth A. Thomas,
CardioVascular BioTherapeutics, Inc., USA
VEGF Receptors
VEGF Receptors
16:30—18:30
Receptors/Ligands II
Kenneth E. Neet,
Rosalind Franklin University, Chicago Medical School, USA
Apoptosis, Cell Cycle, and Differentiation Signaling by Receptor Selective Mutants of NGF
Apoptosis, Cell Cycle, and Differentiation Signaling by Receptor Selective Mutants of NGF
*
Anita B. Roberts,
National Institutes of Health, USA
Smad 3: A Key Player in Pathogenetic Mechanisms Dependent on TGF-beta
Smad 3: A Key Player in Pathogenetic Mechanisms Dependent on TGF-beta
Thomas A.F. Decker,
Vienna Biocenter, University of Vienna, Austria
Regulation of Stat 1 During Host-Pathogen Responses
Regulation of Stat 1 During Host-Pathogen Responses
08:00—11:00
Signaling Molecules I
Michael A. White,
University of Texas Southwestern Medical Center, USA
Complexities in the Functional Organization of Ras/MAP Kinase Cascades
Complexities in the Functional Organization of Ras/MAP Kinase Cascades
David H. Chantry,
ICOS Corporation, USA
Activities and Antagonism of Chemokine Receptors
Activities and Antagonism of Chemokine Receptors
*
Ann Richmond,
Vanderbilt University School of Medicine, USA
Chemokine Receptor Signal Transduction and Receptor Trafficking
Chemokine Receptor Signal Transduction and Receptor Trafficking
14:00—16:00
Workshop 1: Basic Science
*
Thomas A.F. Decker,
Vienna Biocenter, University of Vienna, Austria
*
Sankar Ghosh,
Columbia University, USA
16:30—18:30
Signaling Molecules II
*
Lewis C. Cantley,
Weill Cornell Medicine, USA
Signaling via Phophoinositide Kinase
Signaling via Phophoinositide Kinase
Anjana Rao,
La Jolla Institute for Allergy and Immunology, USA
Gene Regulation by NFAT
Gene Regulation by NFAT
Lee Bardwell,
University of California, Irvine, USA
MAP Kinase Signal Transmission and Specificity
MAP Kinase Signal Transmission and Specificity
08:00—11:00
Transcription/Gene Expression I
*
George R. Stark,
Case Western Reserve University, USA
Genetic Analysis of Interferon-, IL1- and p53- Dependent Signaling
Genetic Analysis of Interferon-, IL1- and p53- Dependent Signaling
Sarah J. Bray,
University of Cambridge, UK
Transcriptional Response to Notch Signaling
Transcriptional Response to Notch Signaling
Richard S. Morrison,
University of Washington, USA
The Role of p53 in Neuronal Cell Death Signaling
The Role of p53 in Neuronal Cell Death Signaling
Michael Karin,
University of California, San Diego, USA
The Regulation of NF-kappaB via the IKK Signaling Cascade
The Regulation of NF-kappaB via the IKK Signaling Cascade
16:30—18:30
Transcription/Gene Expression II
Alain Israël,
Institut Pasteur, France
Genetic and Biochemical Analysis of NF-kappaB Signaling
Genetic and Biochemical Analysis of NF-kappaB Signaling
*
Leslie M. Thompson,
University of California, Irvine, USA
Gene Expression Changes Caused by Skeletal Dysplasia Mutations in FGFR3
Gene Expression Changes Caused by Skeletal Dysplasia Mutations in FGFR3
Steven F. Dowdy,
University of California, San Diego, USA
Differential Regulation of pRB During G1 by Cyclin: Cdks
Differential Regulation of pRB During G1 by Cyclin: Cdks
08:00—11:00
Phenotypic/Cellular Response I
Craig B. Thompson,
Memorial Sloan Kettering Cancer Center, USA
In the Absence of Extracellular Signals, Nutrient Utilization by Metazoan Cells is Insufficient to Maintain Cell Size or Survival
In the Absence of Extracellular Signals, Nutrient Utilization by Metazoan Cells is Insufficient to Maintain Cell Size or Survival
*
Peter N. Devreotes,
Johns Hopkins University, USA
Gradient Sensing Mechanisms in Eucaryotic Cells
Gradient Sensing Mechanisms in Eucaryotic Cells
J. Lawrence Marsh,
University of California, Irvine, USA
Regulating Oncogene Signaling Pathways, Wnts and BMPs
Regulating Oncogene Signaling Pathways, Wnts and BMPs
Michel Aguet,
, Switzerland
Conditional Notch Pathway Mutants in the Mouse
Conditional Notch Pathway Mutants in the Mouse
14:00—16:00
Workshop 2: Clinical Industry
*
Richard L. Kendall,
Amgen Inc., USA
*
Steven F. Dowdy,
University of California, San Diego, USA
16:30—18:30
Phenotypic/Cellular Response II
Anthony J. Wynshaw-Boris,
University of California, San Francisco, USA
Neurodevelopmental Signaling Pathways
Neurodevelopmental Signaling Pathways
*
Claudio Basilico,
New York University School of Medicine, USA
Regulation of Bone Development by FGF Signaling
Regulation of Bone Development by FGF Signaling
Louis M. Staudt,
NCI, National Institutes of Health, USA
Gene Expression Profiling of Lymphoid Malignancies Reveals New Cancer Types and Mechanisms of Malignant Transformation
Gene Expression Profiling of Lymphoid Malignancies Reveals New Cancer Types and Mechanisms of Malignant Transformation
20:00—22:00
Poster Session 4: Phenotypic/Cellular Response/Therapeutics/Applied Signal Transduction
08:00—11:00
Therapeutics/Applied Signal Transduction I
Laurie H. Glimcher,
Dana-Farber Cancer Institute, USA
Transcription Factors that Direct Lineage Commitment in Lymphocytes
Transcription Factors that Direct Lineage Commitment in Lymphocytes
Jeffrey M. Friedman,
Rockefeller University, USA
Leptin and the Regulation of Body Weight
Leptin and the Regulation of Body Weight
Neill A. Giese,
, USA
The Platelet-Derived Growth Factor Receptor (PDGFR) Family as Therapeutic Targets
The Platelet-Derived Growth Factor Receptor (PDGFR) Family as Therapeutic Targets
*
John J. O'Shea,
NIAMS, National Institutes of Health, USA
SCID and TRAPS: Cytokine Receptors and the Pathogenesis of Primary Immunodeficiency and Autoinflammatory Disorders
SCID and TRAPS: Cytokine Receptors and the Pathogenesis of Primary Immunodeficiency and Autoinflammatory Disorders
*Session Chair †Invited, not yet responded.
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