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This meeting took place in 2004



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Stem Cells (B2)


Organizer(s) Fiona M. Watt and Leonard I. Zon
January 23—29, 2004
Keystone Resort • Keystone, CO USA
Abstract Deadline: Sep 23, 2003
Late Abstract Deadline:
Scholarship Deadline:
Early Registration Deadline: Nov 24, 2003

Sponsored in part by the Director's Sponsor Fund

Summary of Meeting:
The most exciting current research to be covered by this conference includes adult stem cell plasticity, clinical applications of stem cells, and human ES cell lines. The major and pivotal problems to be addressed include the controversy surrounding adult stem cell plasticity, and limited data from human ES cells. The goals of this meeting will be reached with a greater emphasis on adult stem cells than previous years and an update on practical applications.

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No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


FRIDAY, JANUARY 23

15:00—19:00
Registration

Shavano Peak Foyer
18:15—19:15
Refreshments

Shavano Peak Foyer
19:15—19:30
Orientation

Crestone/Red Cloud
19:30—20:30
Keynote Address

Crestone/Red Cloud
* Fiona M. Watt, King's College London School of Medicine, UK

Robert ML Winston, Imperial College London, UK
Human Embryonic Stem Cells: Ethical, Political and Practical Considerations


SATURDAY, JANUARY 24

07:00—08:00
Breakfast

Grays Peak 1-3
08:00—11:15
Stem Cell Characteristics. Session Sponsored by the Juvenile Diabetes Research Foundation International

Crestone/Red Cloud
* Austin Smith, University of Cambridge, UK

Yuh-Nung Jan, University of California, San Francisco, USA
Asymmetric Cell Division and Neural Progenitor Fate

Rudolf Jaenisch, Whitehead Institute for Biomedical Research, USA
Nuclear Cloning, Stem Cells and the Reprogramming of the Genome

Irving L. Weissman, Stanford University, USA
Stem Cells and Cancer

Neil Brockdorff, University of Oxford, UK
Short Talk: A Cycle of Inactivation and Reactivation of the Paternal X Chromosome in Early Mouse Embryos

Alex Bortvin, Carnegie Institution of Washington, USA
Short Talk: Origin of the Germline and Developmental Pluripotency Associated (Dppa) Genes

09:20—09:40
Coffee Break

Shavano Peak Foyer
11:15—13:00
Poster Setup

Shavano/Torreys
13:00—22:00
Poster Viewing

Shavano/Torreys
16:30—17:00
Coffee & Snacks Available

Shavano Peak Foyer
17:00—19:00
Directing ES Cell Differentiation and Dedifferentiating Somatic Nuclei

Crestone/Red Cloud
Austin Smith, University of Cambridge, UK
Self-Renewal of Pluripotent Embryonic Stem Cells

Alan O. Trounson, California Institute of Regenerative Medicine, USA
Directed Differentiation of Human Embryonic Stem Cells

Teruhiko Wakayama, RIKEN, Center for Development Biology, Japan
Characterization of Somatic Derived ES Cell (ntES Cell)

Shinya Yamanaka, Center for iPS Cell Research and Application, Kyoto University, Gladstone Institutes, Japan
Short Talk: Upstream and Downstream Regulators of Nanog and ERas, Two Important Molecules in ES Cell Biology

19:00—20:00
Social Hour

Shavano/Torreys
19:30—22:00
Poster Session 1

Shavano/Torreys

SUNDAY, JANUARY 25

07:00—08:00
Breakfast

Grays Peak 1-3
08:00—10:45
Epithelial Stem Cells

Crestone/Red Cloud
* Leonard I. Zon, HHMI/Boston Children's Hospital, USA

Fiona M. Watt, King's College London School of Medicine, UK
Epidermal Stem Cells

Jeffrey M. Rosen, Baylor College of Medicine, USA
Functional Characterization of Mammary Stem Cells in Normal Development and Breast Cancer

Hans C. Clevers, Hubrecht Institute, Netherlands
WNT Signaling in the Intestine

Markus Grompe, Oregon Health & Science University, USA
The Role of Bone Marrow Derived Stem Cells in Liver Injury Responses

10:45—11:15
Genomic Approaches

Crestone/Red Cloud
Rebecca J. Morris, University of Minnesota, USA
Short Talk: Identification of Keratinocyte Stem Cell Regulatory Loci Implicated in Cutaneous Carcinogenesis

Shawn M. Burgess, NHGRI, National Institutes of Health, USA
Short Talk: Microarray Comparison Study of Oct4 Expression in Fish and Mammal Systems

09:20—09:40
Coffee Break

Shavano Peak Foyer
11:15—13:00
Poster Setup

Shavano/Torreys
13:00—22:00
Poster Viewing

Shavano/Torreys
16:30—17:00
Coffee & Snacks Available

Shavano Peak Foyer
17:00—19:00
Muscle Stem Cells

Crestone/Red Cloud
* Irving L. Weissman, Stanford University, USA

Margaret A. Goodell, Baylor College of Medicine, USA
Differentiation and Commitment of Hematopoietic Stem Cells

Helen M. Blau, Stanford University, USA
Plasticity of Adult Stem Cells: Bone Marrow to Brain and Brawn

Giulio Cossu, Stem Cell Research Institute, Italy
Mesoangioblasts, Vessel Derived Pluripotent Stem Cells

Atsushi Asakura, University of Minnesota, Medical School, USA
Short Talk: Muscle Stem Cells for Neovascularization in Skeletal Muscle Regeneration

Amy J. Wagers, Harvard University, USA
Cardiac and Skeletal Muscle Contributions from Bone Marrow Cells

19:00—20:00
Social Hour

Shavano/Torreys
19:30—22:00
Poster Session 2

Shavano/Torreys

MONDAY, JANUARY 26

07:00—08:00
Breakfast

Grays Peak 1-3
08:00—11:15
Haemopoiesis

Crestone/Red Cloud
* Giulio Cossu, Stem Cell Research Institute, Italy

Leonard I. Zon, HHMI/Boston Children's Hospital, USA
Hematopoietic Stem Cells in the Zebrafish

Stuart H. Orkin, Dana-Farber Cancer Institute, USA
Hematopoietic Stem Cells: Origins, Formation, and Maintenance

Shin-Ichi Nishikawa, RIKEN Center for Developmental Biology, Japan
Mesoderm Specification in ES Cell Culture Analyzed by DNA Microarray

Ihor R. Lemischka, Icahn School of Medicine at Mount Sinai, USA
Array Analysis of Bone Marrow Stroma

Matthias Stadtfeld, New York University School of Medicine, USA
Short Talk: Does the Differentiation Plasticity of Hematopoietic Cells Reflect a Developmental Process?

Linheng Li, Stowers Institute for Medical Research, USA
Short Talk: Identification of the Hematopoietic Stem Cell Niche

09:20—09:40
Coffee Break

Shavano Peak Foyer
11:00—13:00
Poster Setup

Shavano/Torreys
13:00—22:00
Poster Viewing

Shavano/Torreys
16:30—17:00
Coffee & Snacks Available

Shavano Peak Foyer
17:00—19:00
Germ Cells

Crestone/Red Cloud
* Rudolf Jaenisch, Whitehead Institute for Biomedical Research, USA

Margaret T. Fuller, Stanford University, USA
Stem Cell Self-Renewal and Differentiation in the Drosophila Male Germline

Allan C. Spradling, HHMI/Carnegie Institute, USA
Gonadal Stem Cells and Cell Plasticity

Kyle E. Orwig, University of Pittsburgh School of Medicine, USA
Stem Cells in the Male Germline

Manju Sharma, The Jackson Laboratory, USA
Short Talk: PLZF is Required for Maintaining the Germ Cell Population in Mouse Testes

19:00—20:00
Social Hour

Shavano/Torreys
19:30—22:00
Poster Session 3

Shavano/Torreys

TUESDAY, JANUARY 27

07:00—08:00
Breakfast

Grays Peak 1-3
08:00—11:15
Brain Stem Cells. Session Sponsored in part by StemCells Inc.

Crestone/Red Cloud
* Shin-Ichi Nishikawa, RIKEN Center for Developmental Biology, Japan

Fred H. Gage, The Salk Institute for Biological Studies, USA
Regulation and Function of Adult Neural Stem Cells

Ronald D. McKay, Lieber Institute for Brain Development, USA
Controlling the Differentiation of ES Cells

David J. Anderson, California Institute of Technology, USA
Growth and Transcription Factors Controlling the Lineage Commitment of Neural Crest Stem Cells

Yoshiki Sasai, RIKEN Center for Developmental Biology, Japan
Directed Differentiation of CNS and PNS Neurons from Embryonic Stem Cells

Akinori Tokunaga, Johns Hopkins University School of Medicine, USA
Short Talk: Mapping Notch Signaling in Mouse Brain

Ichiro Nakano, University of California, Los Angeles, USA
Short Talk: MELK, a Serine/Threonine Kinase, Regulates Proliferation in Neural Stem Cells and Cancers

09:20—09:40
Coffee Break

Shavano Peak Foyer
11:15—13:00
Poster Setup

Shavano/Torreys
13:00—22:00
Poster Viewing

Shavano/Torreys
16:30—17:00
Coffee & Snacks Available

Shavano Peak Foyer
17:00—19:15
Plasticity and Multi-Lineage Potential

Crestone/Red Cloud
* Helen M. Blau, Stanford University, USA

Diane S. Krause, Yale University School of Medicine, USA
Epithelial Differentiation of Bone Marrow-Derived Cells: Fact or Fusion?

Catherine M. Verfaillie, University of Minnesota, USA
Multipotent Adult Stem Cells

Freda D. Miller, Hospital for Sick Children, Canada
Multipotent Stem Cells from Mammalian Dermis

Véronique Azuara, , UK
Short Talk: Chromatin-Based Analysis of Lineage Restriction

Joanna Maldonado-Saldivia, Wellcome Trust/Cancer Research UK, UK
Short Talk: A Molecular Profile of Pluripotency during ES Cell Derivation

19:15—20:15
Social Hour

Shavano/Torreys
19:30—22:00
Poster Session 4

Shavano/Torreys

WEDNESDAY, JANUARY 28

07:00—08:00
Breakfast

Grays Peak 1-3
08:00—11:15
Practical Applications I

Crestone/Red Cloud
* Stuart H. Orkin, Dana-Farber Cancer Institute, USA

Ian Wilmut, University of Edinburgh, UK
Are There Any Normal Clones?

Michael West, Advanced Cell Technology, Inc., USA
Human Therapeutic Cloning and Parthenogenesis

Diana W. Bianchi, NICHD, National Institutes of Health, USA
Short Talk: Pregnancy-Associated Progenitor Cells (PAPCs): A Physiologically-Acquired Novel Fetal Stem Cell?

Olle Lindvall, University of Lund, Sweden
Neuronal Replacement from Endogenous and Grafted Stem Cells in Neurodegenerative Disorders

Curt R. Freed, University of Colorado Denver, USA
Hopes for Stem Cells to Treat Brain Disease

Masatake Osawa, RIKEN Center for Developmental Biology, Japan
Molecular Profilling of Melanocyte Niche

09:20—09:40
Coffee Break

Shavano Peak Foyer
16:30—17:00
Coffee & Snacks Available

Shavano Peak Foyer
17:00—19:00
Practical Applications II

Crestone/Red Cloud
* Ronald D. McKay, Lieber Institute for Brain Development, USA

Alain Fischer, CHU Necker, France
Gene Therapy of Severe Combined Immunodeficiencies

Claudio Bordignon, Science Institute San Raffaele, Italy
Applications of Haemopoietic Stem Cells for Gene Therapy

John E. Wagner, University of Minnesota Medical School, USA
CGMP Manufacture of the Multipotent Adult Progenitor Cell (MAPC) and Strategy for Clinical Testing

Suzanne Jeanine Micallef, Monash University, Australia
Short Talk: Differentiation of Murine Embryonic Stem Cells to pdx-1 Expressing Endodermal Cells

19:00—20:00
Social Hour

Shavano/Torreys
20:00—23:00
Entertainment

Shavano/Torreys

THURSDAY, JANUARY 29

 
Departure


*Session Chair †Invited, not yet responded.


We gratefully acknowledge support for this conference from:


Directors' Fund

These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.

We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1R13NS047606-01




National Institutes of Health
Department of Defense (DOD)

Grant No. W911NF-04-1-0036



We gratefully acknowledge additional support for this conference from:

JDRF March of Dimes Foundation
StemCells, Inc.
 

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations

If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Corporate Relations, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Nick Dua, Senior Director, Communications, Email: nickd@keystonesymposia.org,
Phone:+1 970-262-1179