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This meeting took place in 2008
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Pathological and Physiological Regulation of Cardiac Hypertrophy (A4)
Organizer(s) Leslie A. Leinwand and Eric N. Olson
January 13—18, 2008
Copper Mountain Resort • Copper Mountain, Colorado USA
Abstract Deadline: Sep 14, 2007
Late Abstract Deadline: Oct 17, 2007
Scholarship Deadline: Sep 14, 2007
Early Registration Deadline: Nov 13, 2007
Sponsored by Novartis Institutes for BioMedical Research
Summary of Meeting:
Heart disease remains a leading cause of death and constitutes a complex array of disorders. This meeting will explore new areas of research on how the heart adapts to a wide variety of stimuli including exercise, diet, and genetic background. In the post-genome era, it is now possible to contemplate new heart disease therapies such as through tissue engineering, and stem cell and molecular therapies. The role of microRNAs in regulating cardiac development and disease is an exciting new field of study. We will also consider understanding the mechanisms that animals in nature use to regulate their hearts during hibernation and fasting and feeding.
View Scholarships/Awards
Heart disease remains a leading cause of death and constitutes a complex array of disorders. This meeting will explore new areas of research on how the heart adapts to a wide variety of stimuli including exercise, diet, and genetic background. In the post-genome era, it is now possible to contemplate new heart disease therapies such as through tissue engineering, and stem cell and molecular therapies. The role of microRNAs in regulating cardiac development and disease is an exciting new field of study. We will also consider understanding the mechanisms that animals in nature use to regulate their hearts during hibernation and fasting and feeding.
View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference
SUNDAY, JANUARY 13
MONDAY, JANUARY 14
TUESDAY, JANUARY 15
WEDNESDAY, JANUARY 16
THURSDAY, JANUARY 17
FRIDAY, JANUARY 18
Conference Program Print | View meeting in 12 hr (am/pm) time
SUNDAY, JANUARY 13
19:30—20:30
Keynote Address
08:00—11:00
MicroRNAs in Cardiac Development and Disease
*
Eric N. Olson,
University of Texas Southwestern Medical Center, USA
Deepak Srivastava,
Gladstone Institutes, USA
MicroRNA Regulation of Cardiac Cell Fate, Morphogenesis and Maintenance
MicroRNA Regulation of Cardiac Cell Fate, Morphogenesis and Maintenance
Eva van Rooij,
Hubrecht Institute, Netherlands
Stress Responsive microRNAs and their Control of Cardiac Disease
Stress Responsive microRNAs and their Control of Cardiac Disease
Michel A.J. Georges,
University of Leige GIGA Institute B34, Belgium
Uncovering Roles for miRNAs in Shaping Phenotypic Variability in Domestic Animals
Uncovering Roles for miRNAs in Shaping Phenotypic Variability in Domestic Animals
Minoru Omi,
Tohoku University, Japan
Short Talk: miR-21 is Required for Heart Valve Formation in Zebrafish
Short Talk: miR-21 is Required for Heart Valve Formation in Zebrafish
Prakash K. Rao,
Novartis Institute for Biomedical Research, USA
Short Talk: The Role of MicroRNAs in Muscle Maintenance
Short Talk: The Role of MicroRNAs in Muscle Maintenance
17:00—19:00
Cardiac Remodeling
Eric N. Olson,
University of Texas Southwestern Medical Center, USA
The Myomir Network
The Myomir Network
Jeffery D. Molkentin,
Cincinnati Children's Hospital Medical Center, USA
Unexpected Role for T-type Calcium entry in regulating Cardiac Growth
Unexpected Role for T-type Calcium entry in regulating Cardiac Growth
Michael D. Schneider,
Imperial College London, UK
Cardiac Specification in Embryonic Stem CellsCardiac Specification in Embryonic Stem Cells
Cardiac Specification in Embryonic Stem CellsCardiac Specification in Embryonic Stem Cells
08:00—11:00
Hibernating and Feeding: What We Can Learn from Nature about Maintenance of Cardiac and Skeletal Muscle Mass
*
Nadia A. Rosenthal,
The Jackson Laboratory, USA
Stephen M. Secor,
University of Alabama, USA
The Python Heart: Extreme Regulation of Form and Function
The Python Heart: Extreme Regulation of Form and Function
Thomas G. Marr,
Hiberna Corporation, USA
Profound Mammalian Hibernation
Profound Mammalian Hibernation
Nadia A. Rosenthal,
The Jackson Laboratory, USA
The Role of IGF1 in Maintaining Muscle Mass in Heart Failure
The Role of IGF1 in Maintaining Muscle Mass in Heart Failure
17:00—19:00
The Effects of Heart Disease on Skeletal Muscle
*
Elizabeth M. McNally,
Northwestern University, USA
*
Elizabeth M. McNally,
Northwestern University, USA
Andrew R. Marks,
Columbia University College of Physicians and Surgeons, USA
Remodeling of the RyR1 Channel Complex Causes Impaired Exercise Capacity in Heart Failure
Remodeling of the RyR1 Channel Complex Causes Impaired Exercise Capacity in Heart Failure
Steven R. Houser,
Temple University School of Medicine, USA
Differing Viewpoints on RyR and Heart Failure
Differing Viewpoints on RyR and Heart Failure
08:00—11:00
Modifiers of Heart Disease
Leslie A. Leinwand,
University of Colorado Boulder, USA
A Tale of Two Diets: Diet Affects the Heart
A Tale of Two Diets: Diet Affects the Heart
*
Christine E. Seidman,
Harvard Medical School, USA
Mechanistic Insight through Deep Transcriptional Profiling
Mechanistic Insight through Deep Transcriptional Profiling
Joseph H. Nadeau,
Pacific Northwest Research Institute, USA
Genetic Architecture of Complex Traits in Chromosome Substitution Strains
Genetic Architecture of Complex Traits in Chromosome Substitution Strains
17:00—19:00
Is Blocking Pathologic Hypertrophy a Good Therapeutic Strategy?
*
Michael R. Bristow,
University of Colorado Anschutz Medical Campus, USA
Maladaptive Remodeling of the Human Left Ventricle as a Therapeutic Target
Maladaptive Remodeling of the Human Left Ventricle as a Therapeutic Target
Jeffrey Robbins,
Cincinnati Children's Hospital Medical Center, USA
Pathologic Hypertrophy – an Unfolding Story
Pathologic Hypertrophy – an Unfolding Story
Fady Malik,
Cytokinetics Inc., USA
Can Small Molecules Improve Cardiac Performance?
Can Small Molecules Improve Cardiac Performance?
Joseph A. Hill,
University of Texas Southwestern Medical Center, USA
Short Talk: Cardiomyocyte Autophagy in the Pathogenesis of Heart Failure
Short Talk: Cardiomyocyte Autophagy in the Pathogenesis of Heart Failure
08:00—11:00
Stem Cells and Gene Therapy: The Ongoing Debate
Yuh-Shin Chang,
Massachusetts General Hospital, USA
A Stretch-Activated Survival Pathway in Heart Progenitors and Their Progeny Mediates by the ER/SR Transcription Factor Creb3L2
A Stretch-Activated Survival Pathway in Heart Progenitors and Their Progeny Mediates by the ER/SR Transcription Factor Creb3L2
Elizabeth M. McNally,
Northwestern University, USA
Regeneration and Repair in Skeletal Muscle
Regeneration and Repair in Skeletal Muscle
Elizabeth M. McNally,
Northwestern University, USA
Regeneration and Repair in Skeletal Muscle
Regeneration and Repair in Skeletal Muscle
Ulrich Martin,
Hannover Medical School, Germany
Short Talk: Cardiac Differentiation of Induced Pluripotent Stem (iPS) Cells
Short Talk: Cardiac Differentiation of Induced Pluripotent Stem (iPS) Cells
Jay W. Schneider,
University of Texas Southwestern Medical Center, USA
Short Talk: Small Molecules that Promote Fate and Myocardial Repair
Short Talk: Small Molecules that Promote Fate and Myocardial Repair
17:00—19:00
Tissue Engineering of Valves and Hearts
*
Leslie A. Leinwand,
University of Colorado Boulder, USA
Kristi S. Anseth,
HHMI/University of Colorado, USA
Hydrogel Niches for 3D Culture of Valvular Interstitial Cells: Approaches to Valve Regeneration
Hydrogel Niches for 3D Culture of Valvular Interstitial Cells: Approaches to Valve Regeneration
Thomas Eschenhagen,
University Medical Center Hamburg-Eppendorf, Germany
A Functional Construct of Myocardium for Drug Screening and Target Validation
A Functional Construct of Myocardium for Drug Screening and Target Validation
Doris A. Taylor,
Texas Heart Institute, USA
Cells for Cure of CVD: Science or Science Fiction?
Cells for Cure of CVD: Science or Science Fiction?
*Session Chair †Invited, not yet responded.
We gratefully acknowledge the generous grant for this conference provided by:
We gratefully acknowledge additional support for this conference from:
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American Heart Association's Council on Basic Cardiovascular Sciences |
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We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:
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Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:
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Director of Corporate Relations, Email: sarahl@keystonesymposia.org, Phone:+1 970-262-2690 Click here for more information on Industry Support and Recognition Opportunities. If you are interested in becoming an advertising/marketing in-kind partner, please contact: Nick Dua, Senior Director, Communications, Email: nickd@keystonesymposia.org, Phone:+1 970-262-1179 |
