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This meeting took place in 2008
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Forkhead Transcription Factor Networks in Development, Signaling, and Disease (A3)
Organizer(s) Kenneth S. Zaret, Klaus H. Kaestner and Susan E. Mango
January 13—17, 2008
Zermatt Resort & Spa - Utah • Midway, Utah USA
Abstract Deadline: Sep 12, 2007
Late Abstract Deadline: Oct 15, 2007
Scholarship Deadline: Sep 12, 2007
Early Registration Deadline: Nov 13, 2007
Supported by the Director's Fund
Summary of Meeting:
Forkhead box (FOX) transcription factors were discovered to bind target DNA sites in compacted chromatin, where many other transcription factors cannot bind, and subsequently found to play central roles in regulatory networks that control development, signaling, metabolism, and human disease. The proposed meeting will provide a rare opportunity for cross-fertilization of ideas from very different areas of biological sciences, spanning diverse model organisms and humans, all surrounding this special class of transcription factor. It is expected that the convergence of different models systems, approaches, and thinking will allow unique new insights and advances in each of the scientific domains in which FOXA factors are studied.
View Scholarships/Awards
Forkhead box (FOX) transcription factors were discovered to bind target DNA sites in compacted chromatin, where many other transcription factors cannot bind, and subsequently found to play central roles in regulatory networks that control development, signaling, metabolism, and human disease. The proposed meeting will provide a rare opportunity for cross-fertilization of ideas from very different areas of biological sciences, spanning diverse model organisms and humans, all surrounding this special class of transcription factor. It is expected that the convergence of different models systems, approaches, and thinking will allow unique new insights and advances in each of the scientific domains in which FOXA factors are studied.
View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference
SUNDAY, JANUARY 13
MONDAY, JANUARY 14
TUESDAY, JANUARY 15
WEDNESDAY, JANUARY 16
THURSDAY, JANUARY 17
Conference Program Print | View meeting in 12 hr (am/pm) time
SUNDAY, JANUARY 13
19:30—20:30
Keynote Session
Myles Brown,
Dana-Farber Cancer Institute, USA
Connecting Forkhead Factors and Nuclear Receptors to the Genome
Connecting Forkhead Factors and Nuclear Receptors to the Genome
08:00—11:15
Development and Transcription Networks I
Susan E. Mango,
Harvard University, USA
Making and Shaping the Foregut in C. elegans
Making and Shaping the Foregut in C. elegans
Peter L. J. de Keizer,
UMC Utrecht, Netherlands
Short Talk: The Peptidyl-Isomerase Pin1 Regulates p27kip1 Expression through Inhibition of FOXO Transcription Factors
Short Talk: The Peptidyl-Isomerase Pin1 Regulates p27kip1 Expression through Inhibition of FOXO Transcription Factors
Deborah J. Andrew,
Johns Hopkins University, USA
The Role of the Fox A Protein Fkh in the Drosophila Salivary Gland
The Role of the Fox A Protein Fkh in the Drosophila Salivary Gland
Sven Enerbäck,
University of Gothenburg, Sweden
A Conserved Foxi1 Regulated Genetic Circuit Operates in the Ear, Kidney and Epididymis
A Conserved Foxi1 Regulated Genetic Circuit Operates in the Ear, Kidney and Epididymis
Siew-Lan Ang,
National Institute for Medical Research, UK
Short Talk: Foxa1 and Foxa2 Regulate Midbrain Dopaminergic Neuron Development in a Dosage-Dependent Manner
Short Talk: Foxa1 and Foxa2 Regulate Midbrain Dopaminergic Neuron Development in a Dosage-Dependent Manner
Klaus H. Kaestner,
University of Pennsylvania School of Medicine, USA
The Foxa Genes in the Endocrine Pancreas
The Foxa Genes in the Endocrine Pancreas
17:00—19:00
Chromatin Remodeling and Transcription
*
Susan E. Mango,
Harvard University, USA
Lisa Ann Cirillo,
Medical College of Wisconsin, USA
Chromatin Binding and Perturbation by FoxO1
Chromatin Binding and Perturbation by FoxO1
David Stillman,
University of Utah, USA
Short Talk: Yeast Fkh1 and Fkh2 Proteins Recruit the Sin3 HDAC to Promoters and Can Block Activation By Promoter Bound Factors
Short Talk: Yeast Fkh1 and Fkh2 Proteins Recruit the Sin3 HDAC to Promoters and Can Block Activation By Promoter Bound Factors
Kenneth S. Zaret,
University of Pennsylvania, USA
Distinctive Chromatin Binding and Scanning Properties of Fox Factors
Distinctive Chromatin Binding and Scanning Properties of Fox Factors
19:00—19:15
Discussion About the Creation of New Web Resources for Fox Factors
08:00—11:00
Metabolism and Signaling
*
Deborah J. Andrew,
Johns Hopkins University, USA
Heidi Tissenbaum,
University of Massachusetts Medical School, USA
Complex Regulation by C. elegans FOXO/Daf-16
Complex Regulation by C. elegans FOXO/Daf-16
Hyun Jung Park,
University of Illinois at Chicago, USA
Short Talk: Cell Cycle Regulation of the Forkhead Box M1 (FoxM1) Transcription Factor
Short Talk: Cell Cycle Regulation of the Forkhead Box M1 (FoxM1) Transcription Factor
Andrew G. Dillin,
University of California, Berkeley, USA
Pha4/Foxa, Diet Restriction, and Longevity
Pha4/Foxa, Diet Restriction, and Longevity
Andrei L. Gartel,
University of Illinois, USA
Short Talk: Thiazole Antibiotics that Inhibit FoxM1 are Potential Anticancer Drugs
Short Talk: Thiazole Antibiotics that Inhibit FoxM1 are Potential Anticancer Drugs
Ronald D. McKay,
Lieber Institute for Brain Development, USA
Foxa2, Dopamine Neurons, and Parkinson's Disease
Foxa2, Dopamine Neurons, and Parkinson's Disease
17:00—19:00
Structure and Evolution of Winged Helix Proteins
*
Michelle C. Barton,
University of Texas MD Anderson Cancer Center, USA
Paola Oliveri,
University College London, UK
Fox Genes in Regulatory Networks for Embryo Development and Evolution
Fox Genes in Regulatory Networks for Embryo Development and Evolution
Lin Chen,
University of Southern California, USA
Structural Insights into the Potential Role of FOXP Proteins in the Epigenetic Control of Chromatin Structure
Structural Insights into the Potential Role of FOXP Proteins in the Epigenetic Control of Chromatin Structure
Xiubei Liao,
University of Illinois at Chicago, USA
Folding Stage Dependent Interactions Between HNF-6 and FoxD3 Hint at a Complicated Network in Transcriptional Regulation
Folding Stage Dependent Interactions Between HNF-6 and FoxD3 Hint at a Complicated Network in Transcriptional Regulation
Michael Brent,
Wistar Institute, USA
Short Talk: Structure and Regulation of Human FoxO1 Transcription Factor
Short Talk: Structure and Regulation of Human FoxO1 Transcription Factor
08:00—11:00
The Fox Genes in Human Disease
H. Phillip Koeffler,
Cedars-Sinai Medical Center, USA
FOXA1 and BRCA1 in Breast Cancer
FOXA1 and BRCA1 in Breast Cancer
Michael A. Walter,
University of Alberta, Canada
FOXC1 in Axenfeld-Rieger-Syndrome and Glaucoma
FOXC1 in Axenfeld-Rieger-Syndrome and Glaucoma
Constance Scharff,
Max Planck Institute for Molecular Genetics, Germany
Foxp2 in Learned Avian Vocalizations
Foxp2 in Learned Avian Vocalizations
Simon E. Fisher,
Oxford University, UK
Neurogenetic Pathways Regulated by FOXP2, a Gene Involved in Speech and Language
Neurogenetic Pathways Regulated by FOXP2, a Gene Involved in Speech and Language
Ping Hu,
University of California, Berkeley, USA
Short Talk: A Dual Activator Mechanism Directs Myoblast Specific MyoD Transcription
Short Talk: A Dual Activator Mechanism Directs Myoblast Specific MyoD Transcription
18:00—19:00
Development II
Michelle C. Barton,
University of Texas MD Anderson Cancer Center, USA
Temporal Orchestration of Chromatin Regulation by Foxa1, TGFß and p53
Temporal Orchestration of Chromatin Regulation by Foxa1, TGFß and p53
Peter Carlsson,
Göteborg University, Sweden
FoxF Genes in Murine Embryonic Development
FoxF Genes in Murine Embryonic Development
*Session Chair †Invited, not yet responded.
We gratefully acknowledge support for this conference from:
We gratefully acknowledge the generous grant for this conference provided by:
We gratefully acknowledge additional support for this conference from:
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