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This meeting took place in 2009
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Omics Meets Cell Biology (B2)
Organizer(s) Ruedi H. Aebersold and Tony Pawson
January 25—30, 2009
Beaver Run Resort • Breckenridge, CO USA
Abstract Deadline: Sep 25, 2008
Late Abstract Deadline: Oct 28, 2008
Scholarship Deadline: Sep 25, 2008
Early Registration Deadline: Nov 25, 2008
Sponsored by Bristol-Myers Squibb Company and Novartis Institutes for BioMedical Research
Summary of Meeting:
Apart from deciphering the genomic sequences of hundreds of species, the (human) genome project has catalyzed a wave of technological innovation that is unprecedented in the life sciences. Among its most important products are a number of assays or technologies for the quantitative, global and high throughput analysis of the genome, the molecules derived from the genome and their interactions. These technologies are colloquially described as “OMICS” technologies. The data sets generated by OMICS technologies represent a unique resource for biologists. They have also raised a number of challenging technical and conceptual issues, the solutions to which will ultimately determine the impact of OMICS technologies on biology. These include the error models, completeness and reproducibility of large scale data sets, the question whether and how different data types obtained from the same systems can be integrated and, most importantly, whether validated new biological knowledge has been or will be created either from OMICS data alone or by strategies that combine OMICS and traditional approaches. This conference will bring together the leading experts representing OMICS technologies and leading cell biologists to discuss these issues.
View Scholarships/Awards
Apart from deciphering the genomic sequences of hundreds of species, the (human) genome project has catalyzed a wave of technological innovation that is unprecedented in the life sciences. Among its most important products are a number of assays or technologies for the quantitative, global and high throughput analysis of the genome, the molecules derived from the genome and their interactions. These technologies are colloquially described as “OMICS” technologies. The data sets generated by OMICS technologies represent a unique resource for biologists. They have also raised a number of challenging technical and conceptual issues, the solutions to which will ultimately determine the impact of OMICS technologies on biology. These include the error models, completeness and reproducibility of large scale data sets, the question whether and how different data types obtained from the same systems can be integrated and, most importantly, whether validated new biological knowledge has been or will be created either from OMICS data alone or by strategies that combine OMICS and traditional approaches. This conference will bring together the leading experts representing OMICS technologies and leading cell biologists to discuss these issues.
View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference
SUNDAY, JANUARY 25
MONDAY, JANUARY 26
TUESDAY, JANUARY 27
WEDNESDAY, JANUARY 28
THURSDAY, JANUARY 29
FRIDAY, JANUARY 30
Conference Program Print | View meeting in 12 hr (am/pm) time
SUNDAY, JANUARY 25
19:30—21:30
Keynote Session
Marc W. Kirschner,
Harvard Medical School, USA
Robustness in Biology
Robustness in Biology
David B. Searls,
GlaxoSmithKline Pharmaceuticals, USA
Omic Empiricism
Omic Empiricism
08:00—11:00
Omics and Signaling I
Tony Pawson,
Samuel Lunenfeld Research Institute, Canada
Signaling Networks: Bidirectional Cellular Communication
Signaling Networks: Bidirectional Cellular Communication
*
Rudolf H. Aebersold,
Institute of Molecular Systems Biology, ETH Zürich, Switzerland
Kinase-Substrate Networks
Kinase-Substrate Networks
Ernst Hafen,
Institute of Molecular Systems Biology, ETH Zurich, Switzerland
Control of Cell Growth
Control of Cell Growth
Benjamin Cosgrove,
Stanford University, USA
Multi-Variate Analysis of Signaling Networks Governing Cell Phenotypic Behaviour: Applications to Hepatocyte Toxicity and Pathology
Multi-Variate Analysis of Signaling Networks Governing Cell Phenotypic Behaviour: Applications to Hepatocyte Toxicity and Pathology
17:00—19:00
Omics and Signaling II
Jennifer Mummery Widmer,
Institute of Molecular Biotechnology, Austrian Academy of Sciences, Austria
Short Talk: Genome-Wide Analysis of Notch Signaling during Drosophila External Sensory Organ Development by Transgenic RNAi
Short Talk: Genome-Wide Analysis of Notch Signaling during Drosophila External Sensory Organ Development by Transgenic RNAi
Sarah Teichmann,
Wellcome Sanger Institute, UK
Evolution of Protein Complexes and Protein Interaction Networks
Evolution of Protein Complexes and Protein Interaction Networks
08:00—11:00
Omics and Sub-Cellular Organization I
Laurence Pelletier,
Samuel Lunenfeld Research Institute, Canada
Mechanisms of Mitotic Spindle Assembly
Mechanisms of Mitotic Spindle Assembly
Lucas Pelkmans,
University of Zürich, Switzerland
Population Context Predicts Activity in Human Cells
Population Context Predicts Activity in Human Cells
Christopher J. Bakal,
Institute of Cancer Research, UK
Short Talk: A Systems Genetics Analysis of Rho Signaling
Short Talk: A Systems Genetics Analysis of Rho Signaling
14:30—16:30
Workshop: Available Bioinformatics Resources for Cell Biologists
Scott R. Floyd,
Duke University, USA
Using Advanced Image Analysis Methods in High-Throughput Image-Based Screens for DNA Damage
Using Advanced Image Analysis Methods in High-Throughput Image-Based Screens for DNA Damage
Gary Bader,
University of Toronto, Canada
Biological Network Visualization and Analysis using Cytoscape and Pathway Commons
Biological Network Visualization and Analysis using Cytoscape and Pathway Commons
*
Rolf Apweiler,
European Bioinformatics Institute, UK
Databases and their Utility
Databases and their Utility
17:00—19:00
Omics and Sub-Cellular Organization II
*
Wolfgang P. Baumeister,
Max Planck Institute of Biochemistry, Germany
Cryo-Electron Microscopy: From Molecules to Systems
Cryo-Electron Microscopy: From Molecules to Systems
Peer Bork,
European Molecular Biology Laboratory, Germany
Databases/Data Integration/Computational Biology
Databases/Data Integration/Computational Biology
Oliver Hantschel,
Swiss Federal Institute of Technology Lausanne, Switzerland
Short Talk: Interaction Proteomic, Chemical Proteomic and Transcriptomic Analysis of Abl Oncoproteins and their Inhibitors
Short Talk: Interaction Proteomic, Chemical Proteomic and Transcriptomic Analysis of Abl Oncoproteins and their Inhibitors
08:00—11:00
Omics and Cell Metabolism I
*
Stephen George Oliver,
Cambridge University, UK
Identifying Functional Modules using Metabolic Models
Identifying Functional Modules using Metabolic Models
Uwe Sauer,
Institute of Molecular Systems Biology, ETH Zurich, Switzerland
Unraveling Condition-Specific Networks of Active Metabolic Regulation
Unraveling Condition-Specific Networks of Active Metabolic Regulation
Trey Ideker,
University of California, San Diego, USA
Mapping Gene Regulatory Pathways by Assembly of Physical and Genetic Interactions
Mapping Gene Regulatory Pathways by Assembly of Physical and Genetic Interactions
Marta M. Lipinski,
University of Maryland School of Medicine, USA
Short Talk: A Genome-Wide Image-Based Screen Identifies Global Molecular Mechanisms Regulating Mammalian Autophagy
Short Talk: A Genome-Wide Image-Based Screen Identifies Global Molecular Mechanisms Regulating Mammalian Autophagy
17:00—19:00
Omics Experimental and Computational Strategies I
David M. Sabatini,
Whitehead Institute for Biomedical Research, USA
Large Scale Loss of Function Screens in Mammalian Cells
Large Scale Loss of Function Screens in Mammalian Cells
Sabine P. Cordes,
Mount Sinai Hospital, Canada
The Mouse and the OMICS of Happiness
The Mouse and the OMICS of Happiness
*
Cheryl Arrowsmith,
University of Toronto, Canada
Integrating Structural Genomics and Chemical Genomics for Biology and Medicine
Integrating Structural Genomics and Chemical Genomics for Biology and Medicine
Shohei Koide,
New York University Langone Health, USA
Short Talk: Affinity Clamps: Next-Generation Affinity Reagents
Short Talk: Affinity Clamps: Next-Generation Affinity Reagents
08:00—11:00
Omics and DNA Damage/Cell Cycle Research
Stephen J. Elledge,
Harvard Medical School, USA
Integrative Approaches for DNA Damage and Cell Cycle Analysis
Integrative Approaches for DNA Damage and Cell Cycle Analysis
*
Michael P. Snyder,
Stanford University School of Medicine, USA
Identifying Regulators of Neuronal Differentiation by High-Throughput Screening of Embryonic Stem Cells
Identifying Regulators of Neuronal Differentiation by High-Throughput Screening of Embryonic Stem Cells
Daniel Durocher,
Lunenfeld-Tanenbaum Research Institute, Canada
High Content-High Throughput Screens to Probe the Cellular Response to DNA Damage
High Content-High Throughput Screens to Probe the Cellular Response to DNA Damage
Steven P. Gygi,
Harvard Medical School, USA
Short Talk: Combining Chemical Genetics with Phosphoproteomics: Identifying Direct Cdk1 Targets in Yeast
Short Talk: Combining Chemical Genetics with Phosphoproteomics: Identifying Direct Cdk1 Targets in Yeast
17:00—19:00
Omics Experimental and Computational Strategies II
Christian von Mering,
University of Zurich, Switzerland
The STRING Protein Network Resource: Data Integration for Systems Biology
The STRING Protein Network Resource: Data Integration for Systems Biology
*
A.J. Marian Walhout,
University of Massachusetts Medical School, USA
Gene-Centered Regulatory Networks
Gene-Centered Regulatory Networks
Peter V. Hornbeck,
Cell Signaling Technology, USA
Short Talk: PhosphoSitePlus: A Resource Enabling both System-Wide and Reductionist Studies of Post-translational Modifications
Short Talk: PhosphoSitePlus: A Resource Enabling both System-Wide and Reductionist Studies of Post-translational Modifications
René H. Medema,
Netherlands Cancer Institute, Netherlands
Short Talk: Omics Meets Motor Proteins on the Spindle
Short Talk: Omics Meets Motor Proteins on the Spindle
*Session Chair †Invited, not yet responded.
We gratefully acknowledge support for this conference from:
We gratefully acknowledge the generous grant for this conference provided by:
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